A novel NH4OAc and CuBr(PPh3)3-induced intermolecular Pummerer-type reaction between free (NH)-indoles and dimethylsulfoxide: facile synthesis of 3-methylthiomethyl substituted indoles |
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Authors: | Jin Liu Xianxue Wang Han Guo Xiaokang Shi Xiaoyu Ren Guosheng Huang |
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Affiliation: | 1. State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China;2. Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, Lanzhou University, Lanzhou 730000, PR China |
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Abstract: | A novel NH4OAc/CuBr(PPh3)3-induced intermolecular Pummerer-type reaction between free (NH)-indoles and dimethylsulfoxide is first reported, which offers the 3-methylthiomethyl substituted indoles conveniently and efficiently. |
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