中小学局域网建设的实践

针对中学局域网的建设，本文从实际应用的角度探讨了中学局域网建设的若干重要环节，分析了中学局域网建设中遇到的困难，指出了注意事项。     

大鼠肝ADAMs种类鉴定及肝再生过程中ADAMsmRNA差异分析

以 2 / 3肝切除 (patialhepatectomy ,PH)大鼠为材料 ,利用PT -PCR技术 ,通过ADAMs通用引物初步分析了肝脏中ADAMs种类及PH后恢复 4h和 36h时ADAMsmRNA差异。结果表明 :PH后不同恢复时间ADAMsmRNA的扩增谱带没有差异 ,但扩增谱带的强弱有变化 ;cDNA克隆和测序分析表明 ,大鼠肝脏有ADAM15和ADAM 19mRNA同源序列。     

局部复发性直肠癌的再手术治疗

探讨局部复发性直肠癌(直肠癌根治术后)再次手术的价值、方法、回顾性分析再手术治疗的局部复发性直肠癌33例.结果:21例行根治术,12例行姑息性手术.根治术组和姑息性手术组中位生存期分别为35.2个月(8～82个月)、13个月(2～23个月),再手术5年生存率为34.8%.结论:对于局部复发性直肠癌仍应积极手术,有助于延长生存期,提高生存质量.     

Growth hormone signal transduction

Growth hormone (GH) promotes animal growth by stimulating bone and cartilage cell proliferation, and influences carbohydrate and lipid metabolism. Some of these effects are brought about indirectly via somatomedin induction in hepatocytes, others by acting directly on the target cells. In either case, GH first binds to specific receptors on cells to trigger a sequence of biochemical events culminating in a biological response. Recently much has been learnt about the molecular structure of GH receptor, its binding to ligand, and the ensuing signal transduction events.     

癌痛及其处理对癌症患者生存质量的影响

目的 :探讨癌痛及其处理对癌症患者生存质量的影响。方法 :对 4 8例癌痛患者采用线段分级法(VAS)和 KPS评分法于治疗前后进行评估。结果 :无论是轻度、中度还是重度疼痛 ,均严重影响患者的日常生活、情绪、行走能力、工作、睡眠 ,且随着疼痛程度的加重 ,影响也逐渐加深 ;经三阶梯止痛法治疗后生存质量明显提高 ,治疗前后比较有显著的差异 (P<0 .0 5 )。结论 :疼痛是影响癌症患者生存质量的一个重要因素 ,对癌痛患者应给予必要的止痛治疗 ,以提高患者的生存质量     

Frequent mtDNA mutations and its role in gastric carcinogenesis

In order to disclose the relationship between mutations of mitochondrial DNA (mtDNA) and gastric carcinogenesis, we screened the entire mtDNA sequence in 30 cases of human gastric cancer and matched normal tissues by using denaturing high-performance liquid chromatography (DHPLC) and DNA sequencing. Our data showed that high frequency (66.7%, 20/30) of mitochondrial genome mutation occurred in gastric cancer. Among these variants, 17 cases (56.7%, 17/30) were identified to be somatic mutation. High level mutant frequency was found in ND4, ND5 coding genes and D-loop control region, which was 36.7%, 26.7% and 30% respectively. Comparing with complexes Ⅲ, Ⅳ and Ⅴof the electron transport chain, we found that variants appeared to be more frequent in the subunit genes of complexⅠ. Most of mutations were base substitutions (85.4%, 41/48). Our results suggested that mutations of subunit genes encoding complexⅠ, especially ND3, ND4 and ND5 genes, might contribute to human gastric carcinogenesis.     

中小学教师教育技术能力培训中的绩效评价指标体系

中小学教师教育技术能力培训评价是中小学教师教育技术能力培训活动的构成部分之一。本文将绩效评价的特点引入到教师教育技术培训评价中，结合《中小学教师教育技术能力标准（试行）》，制定了培训绩效评价指标体系，给参与中小学教师教育技术能力培训活动的相关人员提供参考。     

化学一级强化+悬浮填料活性污泥处理污水

针对浙江无锡市惠山区新建的惠山污水处理厂设计工艺,采用化学一级强化处理工艺及悬浮填料活性污泥法,并且就这两种工艺结合组成的二级强化处理工艺在工程实践中的应用作了技术可靠性和经济合理性分析.得出化学一级强化及悬浮填料活性污泥法的处理工艺具有工程投资省、适应水质变化操作灵活等优点.但由于没有太多运行经验,所以需要一个逐步摸索的过程.     

Induction of hemopoietic chimerism in the caprine fetus by intraperitoneal injection of fetal liver cells

Summary Intraperitoneal injection of allogeneic liver cells from 43-day-old male fetuses into normal 60-day female goat fetuses resulted in persistent hemopoietic chimerism in surviving recipients without clinical evidence of graft-versus-host disease. Transplantation of normal fetal liver cells into preimmunocompetent goat fetuses affected with -D-mannosidosis may provide an alternative strategy for evaluating hemopoietic stem cell transplantation in the treatment of human lysosomal storage diseases.     

切削刀具倒棱刃口挤压力的理论计算

根据试验观察．揭出了刀具刃口带负倒棱时的切削模型。在此模型中,刀具刃口 存在一个“金属死区”。以新模型为基础．采用能量法,对高温、高应变率下刀具刃 口的挤压力进行了理论计算。所做工作的特点是：１）在材料变形分析中计入了挤压 层金属绕过刀具刃口时的过剩变形;２）进行有关材料变形与物理特性的计算时,考 虑了温度与应变率的影响。利用新研制的压电式切削测力仪进行验证试验,其结果表 明,理论计算值与实测数据较好一致。