比特力联合甘利欣治疗慢性荨麻疹30例观察

我们于2004年8月-2005年10月应用盐酸西替利嗪（比特力：成都恒瑞制药有限公司）联合甘草酸二铵（甘利欣：连云港正大天晴制药有限公司）治疗慢性荨麻疹，并与单用比特力治疗进行比较，现报道如下。     

异基因间质干细胞输注治疗异染性脑白质营养不良和何勒综合征

异染性脑白质营养不良(MLD)是一种常染色体退行性疾病,由于芳香基硫酸酯酶A缺乏,导致硫酸脑苷酯堆积,中枢和外周神经系统脱髓鞘病变。患者出现严重步态紊乱、痉挛、四肢瘫痪、功能退化,最后丧失全部自主功能。何     

还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

子宫内膜异位症的诊治进展

子宫内膜异位症（简称内异症）是当前妇产科临床最为关注的疾病之一。关注的主要问题是：日趋增加的发病率，病因的不明确，它与不孕的关系以及需要进一步探索的诊断及治疗方法。随着内异症认识的不断深入，在诊断和治疗方面也取得了长足的进展。     

金匮肾气丸加味治疗咽喉异感症50例

目的:观察温肾助阳法在治疗咽喉异感症中的疗效.方法:本组患者共50例,用金匮.肾气丸加味治疗,一个疗程(两周)后观察疗效.结果:治愈34例,好转13例,无效3例,总有效率达94%.结论:温肾助阳法治疗咽喉异感症疗效确切.     

NP方案治疗晚期肺鳞癌36例临床疗效

目的：观察NP方案治疗晚期肺鳞癌36例临床疗效。方法：应用NP（NVB＋DDP）方案，NVB30mg/m^2ivd1.8,DDP30mg/m^2ivgtt d1-3(适当水化）；21－28d为1个周期，至少治疗3个周期。结果：治疗肺鳞癌患36例，近期有效率为55．56％（20／36），初、复治有效率分别为60．7％和37．5％，结论：对不能手术的晚期肺鳞癌，NP方案是一个较为理想的治疗选择，可作为一线临床用药。     

父母为供者的异基因外周血干细胞移植治疗白血病六例

异基因造血干细胞移植是治疗白血病的有效方法，限于我国的国情，青少年患者要获得HLA位点完全相合的供者，机会很小。我们于2003年5月至2004年12月间，以父母为供者，对6例白血病患者进行了HLA位点不相合的干细胞移植，报告如下。     

甲状旁腺腺瘤伴甲状腺腺瘤99Tcm-MIBI显像一例

^99Tc^m-甲氧基异丁基异腈（MIBI）甲状旁腺平面显像诊断甲状旁腺腺瘤有2种阳性显像图，即甲状腺下缘型——单侧甲状腺下极外见浓聚灶和甲状腺腺体型——一侧甲状腺腺内见放射性浓聚灶，前者多见，后者少见。^99Tc^m-MIBI是一种亲肿瘤显像剂，可被甲状旁腺腺瘤和甲状腺腺瘤摄取。因此，鉴别甲状腺腺体型的甲状旁腺腺瘤与甲状腺腺瘤是避免误诊的关键。笔者报道一例罕见甲状旁腺腺瘤伴甲状腺腺瘤的^99Tc^m-MIBI显像结果，供读者参考。     

丙戊酸镁与碳酸锂治疗躁狂发作对照研究

目的 比较丙戊酸镁与碳酸锂治疗躁狂发作的疗效和不良反应。方法 对90例躁狂发作患者随机均分为丙戊酸镁和碳酸锂组，在治疗前，治疗2、4、6周末分别用Bech-Rafaelsen躁狂量表（BRMS）和临床疗效总评量表（CGI）及副反应量表（TESS）评定疗效和不良反应。结果 丙戊酸镁组治疗2周后BRMS总分，及各因子分比治疗前明显降低，且显著低于碳酸锂组，两组治疗6周BRMS总分各因子分均显著低于治疗前，差异显著。治疗2、4、6周末TESS评分，丙戊酸镁组显著低于碳酸锂组，差异有显著性。结论 丙戊酸镁治疗躁狂发作疗效好，起效快，不良反应小。     

急性心肌梗死时心律失常与血清镁的含量分析

目的观察急性心肌梗死时心律失常与血清镁离子的关系。方法选择116例急性心肌梗死病人,按心电监护及心电图结果分为心律失常组与心律正常组。根据血清镁含量将其分为血镁正常组与低镁血症组,观察心律失常与血清镁离子的关系,同时给予低镁病人补镁治疗,观察疗效。结果心律失常组比心律正常组的低血镁率显著增高,经补镁治疗的病人预后优于未予补镁者。结论急性心肌梗死时合并低血镁的病人易发生心律失常,且及时予镁制剂治疗有助于改善病人预后。