Making literature searches easier: a rapid and sensitive search filter for retrieving randomized controlled trials from PubMed.

AIMS: To develop and test the sensitivity and precision of a rapid and simple search filter (RSSF), suitable for busy clinicians wanting to find randomised controlled trials (RCTs) in PubMed. Ideally it should retrieve all the RCTs, but as few irrelevant studies as possible, and be easy to use. METHODS: The RSSF consisted of the search term 'Randomized Controlled Trial' limited to the Publication Type field. Journals that published the highest numbers of diabetes RCTs between 2000 and 2005 were identified, and then handsearched in order define a set of known RCTs. The sensitivity of the RSSF was tested by measuring the proportion of the known RCTs retrieved, and the precision by checking the proportion of the retrieved studies which were RCTs. The RSSF was compared to a highly sensitive search strategy (HSSS) developed for PubMed. Embase was checked for trials not in PubMed. RESULTS: Sixteen journals were found to contain half of all published RCTs in diabetes. 820 diabetes RCTs were identified by handsearching. Measured against these, the RSSF gave a sensitivity of 96.0% (95% CI, 94.8% to 97.1%), and a precision of 93.6% (95% CI 91.7% to 95.0%). Compared to the HSSS, the RSSF reduced the filtering required by 87%. An Embase search for diabetes RCTs found 36 (2.1%) not in PubMed. CONCLUSIONS: A rapid simple search filter for PubMed can find almost all diabetes RCTs, while excluding most studies not required, thereby greatly reducing the time cost of searching and filtering results, and of searching other databases.     

MEDLINE光盘文献的局限及其对策

介绍MEDLINE光盘文献检索的局限性及查找文献的措施.     

探讨Meta分析的循证检索

目的:以有效检索策略为基础的Meta分析,所做的临床决策会对患者产生积极的疗效。文章调查了Meta分析报道检索策略效果证据的范畴。资料来源:对1995-01-01/2004-12-3110年间,EBSCO数据库MED-LINE全文子集进行检索。资料选择:对MEDLINE全文子集中,标引“Meta分析”为出版物类型的论文,进行随机抽样调查(n=100)。资料提炼:以3种方法对这些论文进行分类:论文A类:既足够详细地报道了检索策略(以便于它可能被重复利用),又提供了检索策略效果的证据;论文B类:足够详细地报道了检索策略,但没有提供检索策略效果的证据;论文C类:既没有足够详细地报道检索策略,也没有提供检索策略效果的证据。被分为A类的论文根据所报道的证据水平进一步再分类。资料综合:在最后分析的93篇论文样本中,8篇(8.6%)被分为A类,57(61.3%)篇被分为B类,28篇(30.1%)被分为C类。A类中的论文报道了先前有效的、公开发表了的或者基于专家意见的检索策略。结论:专家评审标准一定要力争得到进一步发展,那就要求Meta分析的作者,对他们检索策略的效果证据要加以报道。     

Is autoimmunology a discipline of its own? A big data-based bibliometric and scientometric analyses

Autoimmunology is a super-specialty of immunology specifically dealing with autoimmune disorders. To assess the extant literature concerning autoimmune disorders, bibliometric and scientometric analyses (namely, research topics/keywords co-occurrence, journal co-citation, citations, and scientific output trends – both crude and normalized, authors network, leading authors, countries, and organizations analysis) were carried out using open-source software, namely, VOSviewer and SciCurve. A corpus of 169,519 articles containing the keyword “autoimmunity” was utilized, selecting PubMed/MEDLINE as bibliographic thesaurus. Journals specifically devoted to autoimmune disorders were six and covered approximately 4.15% of the entire scientific production. Compared with all the corpus (from 1946 on), these specialized journals have been established relatively few decades ago. Top countries were the United States, Japan, Germany, United Kingdom, Italy, China, France, Canada, Australia, and Israel. Trending topics are represented by the role of microRNAs (miRNAs) in the ethiopathogenesis of autoimmune disorders, contributions of genetics and of epigenetic modifications, role of vitamins, management during pregnancy and the impact of gender. New subsets of immune cells have been extensively investigated, with a focus on interleukin production and release and on Th17 cells. Autoimmunology is emerging as a new discipline within immunology, with its own bibliometric properties, an identified scientific community and specifically devoted journals.     

MEDLINE收录山东省各医院1996～2006年论文数量统计

统计山东省部分医院科研论文被国际权威检索系统(MEDLINE)收录情况,并从文献计量学的角度,浅析进一步提高医院论文国际化水平的方法。     

南京军区南京总医院2004年度科技论文排名的思考和建议

为加强医院学术论文管理，促进科技创新和高质量学术论文产出，作者结合国家科技部2005年度“中国科技论文统计分析新闻发布会”的公布结果，对南京军区南京总医院2004年度科学引文索引（SCI）、MEDLINE、国内统计源期刊收录论文、国内论文被引用次数在全国医疗机构中的排名情况以及医院SCI、MEDLINE、国内统计源期刊收录论文产生的学科分布进行分析，认为要保持医院学术论文在全国同类医院领先，必须完善创新体系构建、规范制度化管理和加强论文产出的环节管理。     

1976-2006年MEDLINE 收录青岛医学院附属医院论文统计

通过对青岛大学生医学院附属医院科研论文被国际权威检索系统(MEDLINE)收录情况的分析,评价该院科研水平和学术地位,通过与山东省眼科研究所青岛眼科医院同时期在国内中文期刊上发表的论文进行比较,分析该院目前所存在的不足以及进一步提高科研水平的方法.     

谈MEDLINE数据库循证医学文献检索

循证医学是一种新的医学实践模式。这种新模式要求,临床经验和直觉判断是每一位临床医生必须具备的,但这还不够,临床经验和直觉判断不一定正确和可靠,甚至可能会出现误导。临床医生还必须了解和掌握国内外许多大规模多中心、前瞻性双肓安慰剂对照的临床试验结果,从而获取令人信服的证据。循证医学模式要求医生对患者疾病的防治干预建立在有充分科学证据的基础上,即循证医     

Scientific production and impact of nuclear medicine in Europe: how do we publish?

We performed a bibliometric search covering a 1-year period to evaluate the number and the scientific weight of nuclear medicine papers published from European as compared with other countries. The scientific impact of our discipline was evaluated according to the impact factor of each publication, and we also aimed to identify those countries and topics that are making the principal contributions to the development of our discipline. To this end, a search on MEDLINE (PubMed) was run to find all peer-reviewed articles published between April 2002 and May 2003, using isotope definitions as search terms. A total of 3,292 publications were identified. Of these, 650 were of no nuclear medicine interest, 229 were reviews and 82 had no country specified. In absolute numbers, Europe leads research in nuclear medicine (939 papers, 38.9%) followed by the USA (608 papers, 25.2%). Among European countries, Germany is the nation that is currently making the greatest contribution to the scientific production of nuclear medicine in Europe. Articles concerning the use of nuclear medicine in oncology account for more than one-quarter of all published nuclear medicine papers.     

PubMed与MEDLINE光盘检索不同之处的特点探讨

目的：探讨PubMed检索的主要特点以提高文献的查准率。方法：分别举例介绍PubMed数据时限、超级主题词表、查询词自动转换、主题词检索、临床课题查询、Entrez—PubMed、PubMed Central(PMC)。结果：PubMed检索,除MEDLINE外,还包括PREMEDLINE和OLDMEDLINE,其最早的文献可追溯到1951年。通过查询词转换和匹配及其临床课题研究范围的灵敏度和专指度的选择,使检出的文献更加切题。PubMed还通过与全球NCBI搜索引擎Entrez链接,可互查PMC、核酸序列、蛋白质序列、大分子结构、全基因组、生物体分类学、人类盂德尔遗传及MEDLINE数据库等。检出的记录包括文献条目和摘要,链接后可获取出版商网址上的全文及其在PMC中的免费期刊(160种)原文。结论：PubMed为一般的医学工作者检索文献提供的服务比MEDLINE光盘要多。