KLVFF peptide functionalized nanoparticles capture Aβ42 by co-assembly for decreasing cytotoxicity

The bis(pyrene)-Lys-Leu-Val-Phe-Phe-Gly-poly ethylene glycol (BP-KLVFFG-PEG) based nanoparticles capture Aβ₄₂ by recognition and co-assembly, the length of PEG chain in which leads to different morphologies of coassemblies and capture efficiency. The co-assembly strategy shows a decrease of cytotoxicity, potentially for Alzheimer's disease treatment.     

血液中循环肿瘤细胞捕获与释放方法研究进展

血液中的循环肿瘤细胞(CTCs)与癌症转移密切相关,对CTCs进行检测有利于实现癌症早期诊断。但由于血液中CTCs个数稀少且存在异质性,因此急需发展血液中CTCs的高效分离及检测方法。此外,释放被捕获的细胞并进行后续培养及基因水平分析,将会进一步推进癌症的个性化治疗。本文综述了近年来CTCs捕获及释放的相关研究进展,并展望了其应用前景及发展方向。     

中空多壳层结构在电磁波领域中的应用

中空多壳层结构(HoMSs)是一种以纳米颗粒为结构单元构筑而成的具有多界面、 多维度的微纳米级宏观组装体, 具有次序排列的多个壳层及相互连通的多个空腔, 被认为是电磁波领域极具应用前景的功能材料. 本文主要从电磁波捕获、 传输及能量转换3个角度详细阐述HoMSs在电磁波领域应用中的独特优势, 浅析了HoMSs壳层数目、 壳层厚度、 壳层间距、 壳层组成等结构参数对电磁波传输与利用的影响规律, 并预测了HoMSs在电磁波领域的发展趋势, 以期为实现电磁波的高效利用提供参考.     

一个捕捉与再捕捉模型的贝叶斯分析

本文在无信息先验和Jeffreys先验下 ,就捕捉与再捕捉试验和多次重复的捕捉与再捕捉试验两种情况 ,推导了封闭总体中个体总数N的贝叶斯点估计与区间估计 ,并计算了一个实例     

Magnetic filtration with magnetized granular beds： Basic principles and filter performance

This study is devoted to the explanation of different characteristics of magnetic filtration and the way these characteristics affect the important filtration parameters. Magnetic fields in pores and the force effect of these fields on magnetic particles and the magnetization properties of packed beds composed of ferromagnetic spheres and metal chips are evaluated. The profile of accumulation and capture regions of the particles, the variation of the fluid velocity in these regions and analytic expressions of particle capture radius are presented. The effects of filtration regime parameters on magnetic filter performance were investigated. An analytical expression has been obtained for the dependence of the logarithmic efficiency coefficient on filtration velocity, the geometry of filter elements, the particle size and other parameters of filtration. The stationary and non-stationary equations of the magnetic filtration processes are given. An expression of magnetic filter performance is shown with dimensionless parameters obtained from the filtration system. These relations are useful for calculations in engineering practice, including the design of magnetic filters, provision of suggestions on construction, and optimization and control of filter operation.     

Impulse capture basins of sets under impulse control systems

Given a target contained in a constrained set and an impulse control system governing the evolutions of runs or executions, that are hybrids of continuous and discrete evolutions, this paper studies and provides several characterizations of the capture basin of the target viable in the constrained set. It is the subset of initial runs from which start at least one run viable in the constrained set until it reaches the target in finite time. It also provides algorithms and regulation rules governing the runs that reach the targets while obeying state constraints.     

Cross section measurements of the Pd(p, γ)Ag, Sn(p, γ)Sb, and Sn(α, γ)Te reactions relevant to the astrophysical rp- and γ-processes

Total cross section measurements for the ¹⁰²Pd(p, γ)¹⁰³Ag and ¹¹⁶Sn(p, γ)¹¹⁷Sb reactions have been performed in the proton energy range 2.6 to 4.25 MeV, and for the ¹¹²Sn(α, γ)¹¹⁶Te reaction over the alpha beam energy range 7.0 to 10.5 MeV. An activation technique was used in which gamma rays from decays of the reaction products were detected off-line by two hyper-pure germanium detectors in a low background environment. Where possible, reaction rates are derived and the results compared to those of calculations generated by the NON-SMOKER and the MOST statistical model codes so as to judge their applicability for describing the cross sections needed for network calculations of nucleosynthesis in explosive astrophysical environments via the γ- and rp-processes.     

Gain and transient photoresponse of quantum well infrared photodetectors: a detailed ensemble Monte Carlo study

We investigate different gain characteristics observed on quantum well infrared photodetectors (QWIPs) fabricated with various material systems, and the effects of barrier material properties on the device characteristics through detailed ensemble Monte Carlo simulations. When the energy spacing between the central and satellite valleys is increased, the improvement in the excited electron lifetime is found to be much stronger than that in the average electron velocity in the device. According to our results, relatively high gain observed in InP/In_0.53Ga_0.47As QWIPs under large bias is not due to the higher mobility in InP as suggested earlier; it can mainly be attributed to higher excited electron lifetime as a result of relatively large Γ–L energy spacing. We discuss the details of the fast part of the Al_0.3Ga_0.7As/GaAs QWIP transient photoresponse, which exhibits three regions with different decay characteristics under a short pulse of radiation. The duration of the final region, during which the electrons excited near the emitter are extracted from the collector, is observed to be considerably long due to the dispersion of the photoelectrons. The photoresponse time rapidly decreases with increasing bias under low bias, and nearly saturates at 10 ps under large bias being 40% larger than the average transit time estimated by dividing the device length to the average steady-state electron velocity in device. We also investigate the effects of the interface reflections on the photoresponse time.     

Bounds on the length of a game of Cops and Robbers

In the game of Cops and Robbers, a team of cops attempts to capture a robber on a graph $G$. All players occupy vertices of $G$. The game operates in rounds; in each round the cops move to neighboring vertices, after which the robber does the same. The minimum number of cops needed to guarantee capture of a robber on $G$ is the cop number of $G$, denoted $c\left(G\right)$, and the minimum number of rounds needed for them to do so is the capture time. It has long been known that the capture time of an $n$-vertex graph with cop number $k$ is $O\left(n^{k+1}\right)$. More recently, Bonato et al. (2009) and Gaven?iak (2010) showed that for $k=1$, this upper bound is not asymptotically tight: for graphs with cop number 1, the cop can always win within $n?4$ rounds. In this paper, we show that the upper bound is tight when $k\ge 2$: for fixed $k\ge 2$, we construct arbitrarily large graphs $G$ having capture time at least ${\left(\frac{\left|V\left(G\right)\right|}{40k^4}\right)}^{k+1}$.In the process of proving our main result, we establish results that may be of independent interest. In particular, we show that the problem of deciding whether $k$ cops can capture a robber on a directed graph is polynomial-time equivalent to deciding whether $k$ cops can capture a robber on an undirected graph. As a corollary of this fact, we obtain a relatively short proof of a major conjecture of Goldstein and Reingold (1995), which was recently proved through other means (Kinnersley, 2015). We also show that $n$-vertex strongly-connected directed graphs with cop number 1 can have capture time $\Omega \left(n^2\right)$, thereby showing that the result of Bonato et al. (2009) does not extend to the directed setting.