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排序方式: 共有123条查询结果,搜索用时 0 毫秒
1.
Ca-P仿生人工骨材料的设计与制备 总被引:2,自引:0,他引:2
本文设计了用磷酸钙生物陶瓷制备仿生人工骨的工艺路线 ,从原料合成、材料成型和烧结等讨论了仿骨材料的制备方法 相似文献
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短棒状纳米羟基磷灰石的湿法合成及表征 总被引:16,自引:5,他引:16
通过简单湿法合成制备了短棒状纳米羟基石颗粒,粉体在不同的温度下进行了热处理,并用红外光谱、透射电镜及X射线衍射等实验手段对组织、结构及热稳定性进行了表征。研究表明,将适当比例的(NH4)2HPO4和Ca(NO3)2晶体混合、振荡、陈化后提纯、烘干,可制备出长约30-40nm,直径约10-20nm的短棒状纳米羟基灰石颗粒,这种颗粒结构与通常的针状结构相比更接近于人体骨磷灰石(长约40-60nm,宽约20nm);该颗粒具有较好的热稳定性,600℃以下热处理后,颗粒结构、尺寸和形貌基本不变,分散性较好;900℃热处理后,颗粒明显长大并严重团聚。 相似文献
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Porous β-tricalcium phosphate bioceramic (PTCP) has important roles in surgical implants because of good biocompatibility. But the low compressive strength of the ceramic limits its application. The preparation of PTCP was improved with the adjustment of the constituents and the sintering-process. A new type of PTCP material with high compressive strength was made. The compositions, microstructure and properties of PTCP were analyzed by TG-DSC, XRD, TEM, SEM and so on. The result indicates that stearic acid burns sufficiently and gives out carbon dioxide and water vapor when slowly heated between 200 ℃ and 400 ℃ so that the porous structure like coral in β-TCP bioceramic is formed. Through crystallization at 470 ℃ and 570 ℃, more CaO-P2O5 glass-cement is converted into crystallite-glass, which is beneficial for improving the compressive strength of β-TCP bioceramic.PTCP can form a support action in bone imperfect section with good solubility. 相似文献
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ZHU Xiu-hong WANG Cong-zeng KOU Bin-da SU Xue-kuan ZHANG Wen-quan College of Materials Science Engineering Beijing University of Technology Beijing China 《材料热处理学报》2004,25(5)
In recent years the biomedical material has been widelydeveloped,and application that the implant materialssubstitute for hard organ has attracted much attention.Titanium alloys are frequently utilized as skeletonimplant and modification materials because of theirlight density,high strength and proper biocompatibility.However,titanium alloys are bioinertial materials,which are not beneficial to the performance of organiccoalescence,so they are not yet the ideal implantmaterials.Therefore,impro… 相似文献
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《Drug development and industrial pharmacy》2013,39(5):538-546
Local antimicrobial delivery is a potential area of research conceptualized to provide alternative and better methods of treatment for cases, as osteomyelitis where avascular zones prevent the delivery of drugs from conventional routes of administration. Drug-loaded polymers and calcium phosphates as hydroxyapatites have been tried earlier. Bioactive glasses are bone-filling materials used for space management in orthopedic and dental surgery. A new bioactive glass (SSS2) was synthesized and fabricated into porous scaffold with a view to provide prolonged local delivery of gatifloxacin and fluconazole as suitable for the treatment of osteomyelitis. The new SSS2 was characterized by Fourier transform infrared (FTIR) and X-ray diffraction (XRD) analyses. In addition, the bioactivity of the SSS2 glass and resulting scaffold was examined by in vitro acellular method and ascertained by FTIR and XRD. The pore size distribution was analysed by mercury intrusion porosimetry and the release of drugs from scaffolds were studied in vitro. The glass and the resulting scaffolds were bioactive indicating that they can bond with bone in vivo. The scaffolds were porous with pores predominantly in the range of 10–60 µm, released the drugs effectively for 6 weeks and deemed suitable for local delivery of drugs to treat osteomyelitis. 相似文献
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在钛基上电泳沉积羟基磷灰石生物陶瓷涂层的研究 总被引:7,自引:0,他引:7
将羟基磷灰石(HAP)电泳沉积在钛基材上,得到了结构稳定的HAP生物陶瓷涂层。研究了电场强度、悬浮液温度、电泳时间、分散介质及HAP浓度对涂层形貌的影响。通过红外光谱仪(FTIR)和X射线衍射仪(XRD)对涂层的组成及结构进行了分析,并采用扫描电镜(SEM)对涂层煅烧前后的微观形貌进行了观察。结果表明:在正丁醇作为分散剂、悬浮液温度30℃、电场强度250V/cm、电泳时间300s以及HAP浓度5.0g/L的条件下可制得形貌较好的HAP生物陶瓷涂层;经二次电泳沉积及煅烧后得到的HAP生物陶瓷涂层均匀致密. 相似文献
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