Comparision of Different Radiotherapy Planning Techniques for Breast Cancer after Breast Conserving Surgery

Objectives:To compare different radiotherapy planning techniques for breast cancer after breast conserving surgery.Materials and methods: Eighteen patients with breast cancer who underwent breast conserving surgery were selected.For each patient four different whole breast irradiation techniques including Tan, fIMRT, iIMRT and VMAT werecompared to the conventional tangential technique (Tan). Results: Mean maximum point dose (Dmax) for Tan, fIMRT,iIMRT and VMAT were 110.17% (±1.87), 105.89% (±1.13), 106.47% (±0.92) and 106.99% (±1.16) (p<0.001). Meanminimum point dose (Dmin) from Tan was 84.02% (±3.68) which was significantly higher than those from fIMRT,iIMRT and VMAT which were 76.57% (±11.4), 67.69 %( ±19.20) and 80.69% (±7.06) (p<0.001). Only the meanV95 of fIMRT was significantly less than Tan (p=0.01). Mean percentage of volume receiving ≥ 20 Gy (V20Gy) andmean doses of the ipsilateral lung were 17.09% and 953.05 cGy, 16.60% and 879.20 cGy, 14.79% and 772.26 cGy,15.32% and 984.34 cGy for Tan, fIMRT, iIMRT and VMAT. Only iIMRT had a significantly lower mean V20Gy andthe mean dose to ipsilateral lung in comparison with Tan. Significantly, high mean doses to the contralateral breast(498.07 cGy, p<0.001) were observed in VMAT. Conclusion: The conventional tangential technique provides adequatedose coverage but resulted in high dose-volumes. The iIMRT and fIMRT had significantly smaller high dose-volumesand better conformity. VMAT demonstrated excellent dose homogeneity and conformity but an increased low-dosevolume outside the target should be of concern.