全文获取类型
收费全文 | 477篇 |
免费 | 30篇 |
学科分类
医药卫生 | 507篇 |
出版年
2023年 | 1篇 |
2022年 | 5篇 |
2021年 | 14篇 |
2020年 | 11篇 |
2019年 | 6篇 |
2018年 | 13篇 |
2017年 | 10篇 |
2016年 | 12篇 |
2015年 | 17篇 |
2014年 | 14篇 |
2013年 | 23篇 |
2012年 | 32篇 |
2011年 | 37篇 |
2010年 | 28篇 |
2009年 | 25篇 |
2008年 | 29篇 |
2007年 | 13篇 |
2006年 | 22篇 |
2005年 | 29篇 |
2004年 | 23篇 |
2003年 | 16篇 |
2002年 | 11篇 |
2001年 | 10篇 |
2000年 | 4篇 |
1999年 | 7篇 |
1998年 | 8篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 4篇 |
1991年 | 9篇 |
1990年 | 10篇 |
1989年 | 9篇 |
1988年 | 1篇 |
1987年 | 2篇 |
1986年 | 7篇 |
1985年 | 6篇 |
1984年 | 6篇 |
1983年 | 4篇 |
1982年 | 7篇 |
1981年 | 5篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1973年 | 1篇 |
1925年 | 1篇 |
排序方式: 共有507条查询结果,搜索用时 15 毫秒
1.
News of the EAR
EAR General Assembly, Vienna, 8 March 1995President's Report 相似文献2.
3.
Magne Aldrin Ragnhild Raastad Ingunn Fride Tvete Dag Berild Arnoldo Frigessi Truls Leegaard Dominique L. Monnet Mette Walberg Fredrik Müller 《Statistics in medicine》2013,32(8):1407-1418
Association between previous antibiotic use and emergence of antibiotic resistance has been reported for several microorganisms. The relationship has been extensively studied, and although the causes of antibiotic resistance are multi‐factorial, clear evidence of antibiotic use as a major risk factor exists. Most studies are carried out in countries with high consumption of antibiotics and corresponding high levels of antibiotic resistance, and currently, little is known whether and at what level the associations are detectable in a low antibiotic consumption environment. We conduct an ecological, retrospective study aimed at determining the impact of antibiotic consumption on antibiotic‐resistant Pseudomonas aeruginosa in three hospitals in Norway, a country with low levels of antibiotic use. We construct a sophisticated statistical model to capture such low signals. To reduce noise, we conduct our study at hospital ward level. We propose a random effect Poisson or binomial regression model, with a reparametrisation that allows us to reduce the number of parameters. Inference is likelihood based. Through scenario simulation, we study the potential effects of reduced or increased antibiotic use. Results clearly indicate that the effects of consumption on resistance are present under conditions with relatively low use of antibiotic agents. This strengthens the recommendation on prudent use of antibiotics, even when consumption is relatively low. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
4.
5.
Ethical implications of home telecare for older people: a framework derived from a multisited participative study 下载免费PDF全文
Maggie Mort PhD Celia Roberts PhD Jeannette Pols PhD Miquel Domenech PhD Ingunn Moser PhD The EFORTT investigators 《Health expectations》2015,18(3):438-449
Context
Telecare and telehealth developments have recently attracted much attention in research and service development contexts, where their evaluation has predominantly concerned effectiveness and efficiency. Their social and ethical implications, in contrast, have received little scrutiny.Objective
To develop an ethical framework for telecare systems based on analysis of observations of telecare‐in‐use and citizens’ panel deliberations.Design
Ethnographic study (observation, work shadowing), interviews, older citizens’ panels and a participative conference.Setting
Participants’ homes, workplaces and familiar community venues in England, Spain, the Netherlands and Norway 2008–2011.Results
Older respondents expressed concerns that telecare might be used to replace face‐to‐face/hands‐on care to cut costs. Citizens’ panels strongly advocated ethical and social questions being considered in tandem with technical and policy developments. Older people are too often excluded from telecare system design, and installation is often wrongly seen as a one‐off event. Some systems enhance self‐care by increasing self‐awareness, while others shift agency away from the older person, introducing new forms of dependency.Conclusions
Telecare has care limitations; it is not a solution, but a shift in networks of relations and responsibilities. Telecare cannot be meaningfully evaluated as an entity, but rather in the situated relations people and technologies create together. Characteristics of ethical telecare include on‐going user/carer engagement in decision making about systems: in‐home system evolution with feedback opportunities built into implementation. System design should be horizontal, ‘two‐way’/interactive rather than vertical or ‘one‐way’. An ethical framework for telecare has been developed from these conclusions (Table 1). 相似文献6.
7.
Jenny Mullen Lasse Vestli Bkken Timo Trmkangas Lena Ekstrm Magnus Ericsson Ingunn R. Hullstein Jenny J. Schulze 《Drug testing and analysis》2020,12(6):720-730
The steroidal module of the Athlete Biological Passport (ABP) aims to detect doping with endogenous steroids, e.g. testosterone (T), by longitudinally monitoring several biomarkers. These biomarkers are ratios combined into urinary concentrations of testosterone and metabolically related steroids. However, it is evident after 5 years of monitoring steroid passports that there are large variations in the steroid ratios complicating its interpretation. In this study, we used over 11000 urinary steroid profiles from Swedish and Norwegian athletes to determine both the inter‐ and intra‐individual variations of all steroids and ratios in the steroidal passport. Furthermore, we investigated if the inter‐individual variations could be associated with factors such as gender, type of sport, age, time of day, time of year, and if the urine was collected in or out of competition. We show that there are factors reported in today's doping tests that significantly affect the steroid profiles. The factors with the largest influence on the steroid profile were the type of sport classification that the athlete belonged to as well as whether the urine was collected in or out of competition. There were also significant differences based on what time of day and time of year the urine sample was collected. Whether these significant changes are relevant when longitudinally monitoring athletes in the steroidal module of the ABP should be evaluated further. 相似文献
8.
Kristjansson K Manolescu A Kristinsson A Hardarson T Knudsen H Ingason S Thorleifsson G Frigge ML Kong A Gulcher JR Stefansson K 《Hypertension》2002,39(6):1044-1049
We performed a genomewide scan with 904 microsatellite markers using 120 extended Icelandic families with 490 hypertensive patients. The families were identified by cross-matching a list of hypertensive patients from the Hypertension Clinic of the University Hospital (Landspitalinn) in Iceland with a genealogy database of the entire Icelandic nation. After adding 5 markers, we found linkage to chromosome 18q with an allele-sharing LOD score of 4.60 (P=2.1x 10(-6)). These results provide evidence for a novel susceptibility gene for essential hypertension on chromosome 18q and show that it is possible to study the genetics of essential hypertension without stratifying by subphenotypes. 相似文献
9.
Kim Fejgin Jacob Nielsen Michelle R. Birknow Jesper F. Bastlund Vibeke Nielsen Jes B. Lauridsen Hreinn Stefansson Stacy Steinberg Helge B.D. Sorensen Troels E. Mortensen Peter H. Larsen Ib V. Klewe Søren V. Rasmussen Kari Stefansson Thomas M. Werge Pekka Kallunki Kenneth V. Christensen Michael Didriksen 《Neuropsychopharmacology》2014
10.
Ingunn Amble Tore Gude Sven Stubdal Tuva Oktedalen Anne Marie Skjorten Bror Just Andersen 《Psychotherapy research》2013,23(4):504-507
AbstractObjective: Monitoring of ongoing psychotherapy is of crucial importance in improving the quality of mental health care by detecting therapies being off track, which requires that the instrument used is psychometrically sound. This study investigates the psychometric properties of the Norwegian version of the Outcome Questionnaire 45.2 (OQ-45) and situates the results in an international context.Method: Data from one non-clinical sample (N = 338) and one clinical sample (N = 560) were compared to international samples investigating reliability, cut-offs, and factor structure. Results: The results show adequate reliability and concurrent validity. Conclusions: The means, clinical cut-offs, and the reliable change index vary across countries. However, the means of the OQ-45 for nonclinical samples correlate highly with external values of national well-being, indicating that the OQ-45 is a valid instrument internationally. The factor analyses in the present study do not confirm the hypothesized factor structure of the OQ-45, but are similar to the results internationally. 相似文献