TiO2/CuInS2-sensitized structure for sensitive photoelectrochemical immunoassay of cortisol in saliva

Journal of Solid State Electrochemistry - Cortisol, a steroid hormone, has been confirmed as a kind of biomarker that reflects the stress response of psychobiology and related adverse health...     

光源加热型高灵敏度光纤热式风速计

卫星钟差确定受限于经典测量的散粒噪声极限,钟差测量精度仅为ns量级。基于军民领域对高精度时间基准的迫切需求,提出了一种基于双路六延迟传送带量子纠缠光的卫星钟差测量方案,并且该方案以传送带协议为基础。首先,通过自发参量下转换制备了频率纠缠光信号。然后,利用HOM (Hong-Ou-Mandel)干涉仪对频率纠缠光信号进行了二阶关联检测解算,进而得到了钟差信息。最后,仿真分析了相关参数对钟差测量的影响。所提方案无需进行到达时间测量,不受色散效应及星地距离的影响,在理论上可以实现ps量级的卫星钟差测量。     

基于多巴胺-量子点的比色免疫分析法对甲胎蛋白的高灵敏检测

基于抗原抗体识别特异性,以多巴胺-Mn/ZnS量子点(DA-QDs)为反应媒介,紫外可见分光光度计为检测手段,采用柠檬酸钠还原法制备金纳米颗粒(AuNPs),其表面用辣根过氧化物酶(HRP)和羊抗小鼠免疫球蛋白G (IgG)修饰获得功能化二抗(IgG-AuNPs-HRP)作为信号放大标签,构建一种简便高灵敏的检测方法....     

Enhanced Immunosensor Using a Handheld pH Meter for the Point-of-Care,Sensitive Detection of Prostate Specific Antigen

An enhanced handheld pH meter based immunosensor was proposed for point-of-care, quantitative determination of prostate specific antigen (PSA). Monoclonal antibody-functionalized magnetic beads (MB-Ab₁) were prepared to capture PSA in sample, and subsequently bond to polyclonal antibody-immobilized gold nanoparticles-polyamide-amine dendrite-lead ion (GO-PAMAM-Pb²⁺) and dispersed in H₂S solution. Based on negative Gibbs free energy of formation, PbS (solubility product constant K_sp=8.0×10⁻²⁸ was formed by reaction of Pb²⁺ and H₂S. Hence, the pH of solution increased due to the H⁺ appeared, and the resulting pH value was monitored by a handheld pH meter.     

A dual-mode biosensor for salivary cortisol with antibody-aptamer sandwich pattern and enzyme catalytic amplification

Journal of Solid State Electrochemistry - A split-type and dual-mode (photoelectrochemical and electrochemical, PEC and EC) biosensor was developed for non-invasive and sensitive detection of...