一种适合于网络专家系统的通用理论(英文)

描述运用于工业自动化的一种自适应自学习方法。基于此方法,Ａｐｔｒｏｎｉｘ公司开发出一套通用软件工具－ＳＴＩＭＴＭ,并应用于不同工业领域。ＳＴＩＭ可用于构造各类专家系统。基于因素空间理论,ＳＴＩＭ具有一系列独特之处,比如自动化、自学习,以及自翻译。如果与因特网,嵌入式控制器以及可编程逻辑控制器等结合使用,ＳＴＩＭ则成为一个十分有效的工具,可应用于远程连通与控制、模式识别、机器故障诊断,以及自动化加工过程中的传感器数据融合     

Stem cells, cancer, and cancer stem cells.

Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine. Perhaps the most important and useful property of stem cells is that of self-renewal. Through this property, striking parallels can be found between stem cells and cancer cells: tumours may often originate from the transformation of normal stem cells, similar signalling pathways may regulate self-renewal in stem cells and cancer cells, and cancer cells may include 'cancer stem cells' - rare cells with indefinite potential for self-renewal that drive tumorigenesis.     

Nesting phenology and productivity of birds in the White and Inyo Mountains, California, as assessed with nest-boxes

Nest-boxes were monitored from 1988 to 1992 on 5 grids in the pinyon-juniper ( Pinus-Juniperus ) woodlands of the White and Inyo Mountains, California, to determine breeding phenology and productivity of cavity-nesting birds, and characteristics of used and non-used nest-boxes. We found a total of 112 nests of 6 species. Bewicks Wrens ( Thryomanes bewicki i; 64 nests), Mountain Chickadees ( Poecile gambeli ; 18), Ash-throated Flycatchers ( Myiarchus cinerascens ; 12), and Juniper Titmice ( Baeolophus ridgwayi ; 11) were the most common species utilizing the boxes. Nest phenology and numbers of young were similar to values reported elsewhere in the literature for the species, although nesting success for Mountain Chickadees appeared lower in our study. Chickadees were associated with relatively dense, mature vegetation on southern slopes. Juniper Titmice used areas with tall juniper shrubs and generally sparse vegetation. Bewicks Wrens used areas with short trees, sparse vegetation, and many stumps. Nest-boxes were underutilized (< 15% use) by most species relative to their availability and relative to detected abundances of the species. We suggest that nest-boxes can provide valuable breeding biology information and can potentially increase the productivity of rare and cavity-limited species.     

Habitat characteristics of small mammals in southeastern Utah

We describe habitat characteristics of 8 small mammal species occurring in the Manti-LaSal National Forest in southeastern Utah. Thirty-seven grids across 7 vegetation types were sample by live-trapping from May through October 1994 and 1995. Logistic regression models of habitat measurements correctly classified small mammal presence 36%-87% of the time. Except for 1 instance, 4 Peromyscus species present in a specific vegetation type were negatively associated with forb or grass cover. Microtus montanus was present primarily on mesas and was positively associated with tall tree and low shrub cover. Neotoma mexicana was present only in canyons and was found primarily in the pinyon-juniper ( Pinus edulis-Juniperus osteosperma ) vegetation type. Tamias spp. was present in all vegetation types. Our results allow better management of these species by providing greater understanding of their use of habitat within vegetation types.     

Habitat use by small mammals in southeastern Utah, with reference to Mexican Spotted Owl management

We determined temporal and spatial differences in abundance and habitat use by small mammals in southeastern Utah as part of an effort to enhance management of the Mexican Spotted Owl ( Strix occidentalis lucida ), listed by the federal government as threatened. Woodrats ( Neotoma spp.) were captured only in canyons and most frequently in the pinyon-juniper ( Pinus edulis-Juniperus osteosperma ) vegetation type. White-footed mice ( Peromyscus spp.) were found in a variety of vegetation types in both canyons and mesas. The deer mouse ( P. maniculatus ) was generally the most frequently captured species among vegetation types. We found seasonal and yearly differences in relative abundance of each small mammal species. Our data suggest that the pinyon-juniper vegetation type within canyons is an important component of Mexican Spotted Owl habitat.     

克拉2气田石油地质特征

克拉2气田位于库车拗陷克拉苏构造带中段, 是双重构造中呈串珠状分布的一系列褶皱中的一个局部构造. 含气层系以下白垩统巴什基奇克组砂岩为主, 其次为下第三系库姆格列木群白云岩段和砂砾岩段及下白垩统巴西盖组砂岩. 天然气中甲烷含量大于97%, 属于干气, 气源为侏罗系煤系地层. 克拉2号构造圈闭形成于西域期, 成藏期晚. 下第三系厚层膏盐区域盖层形成的良好封盖条件及其成藏期晚是克拉2大气田得以很好保存的根本原因. 克拉2气田的异常高压是由于西域期来自北部的强烈构造挤压作用而形成的.     

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis

We recently identified angiogenin (ANG) as a candidate susceptibility gene for amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized by adult-onset loss of motor neurons. We now report the finding of seven missense mutations in 15 individuals, of whom four had familial ALS and 11 apparently 'sporadic' ALS. Our findings provide further evidence that variations in hypoxia-inducible genes have an important role in motor neuron degeneration.     

中华绒螯蟹首次排卵后卵巢发育的组织学研究

利用组织切片技术,结合外观特征,在光学水平对江苏南通地区第一次排卵后18天内（即卵巢的二次发育）的中华绒螯蟹的卵巢发育进行组织学和细胞学的观察研究．本实验可以观察到卵细胞发育的四个不同时期：初级卵母细胞小生长期、初级卵母细胞大生长期、成熟期以及退化时期的卵细胞．排卵后的卵巢在营养贫乏的情况下,出现直接退化现象;而在营养丰富的情况下,处于大生长前期的卵细胞则会迅速生长,为二次排卵做好准备．     

Mutational analysis of a protein-folding pathway

The effects of amino-acid replacements on the disulphide-coupled folding pathway of bovine pancreatic trypsin inhibitor have been examined. Replacements at three sites destabilize the native protein relative to the unfolded state, but have different effects on the relative stabilities of the disulphide-bonded folding intermediates, thus allowing the roles of the altered residues during folding to be distinguished.     

Superoxide activates mitochondrial uncoupling proteins.

Uncoupling protein 1 (UCP1) diverts energy from ATP synthesis to thermogenesis in the mitochondria of brown adipose tissue by catalysing a regulated leak of protons across the inner membrane. The functions of its homologues, UCP2 and UCP3, in other tissues are debated. UCP2 and UCP3 are present at much lower abundance than UCP1, and the uncoupling with which they are associated is not significantly thermogenic. Mild uncoupling would, however, decrease the mitochondrial production of reactive oxygen species, which are important mediators of oxidative damage. Here we show that superoxide increases mitochondrial proton conductance through effects on UCP1, UCP2 and UCP3. Superoxide-induced uncoupling requires fatty acids and is inhibited by purine nucleotides. It correlates with the tissue expression of UCPs, appears in mitochondria from yeast expressing UCP1, and is absent in skeletal muscle mitochondria from UCP3 knockout mice. Our findings indicate that the interaction of superoxide with UCPs may be a mechanism for decreasing the concentrations of reactive oxygen species inside mitochondria.