Acupuncture for Moderate to Severe Allergic Rhinitis: A Non-randomized Controlled Trial

Objective

To evaluate the effect and safety of acupuncture therapy on patients with moderate to severe allergic rhinitis.

Methods

A non-randomized controlled design was used to compare between the acupuncture group and the medication group. The acupuncture group received 8-week acupuncture therapy, and the medication group received budesonide nasal spray with cetirizine tablets for 8 weeks. The clinical symptoms and signs were analyzed before treatment, at 4 and 8 weeks after the start of treatment, and at 12 weeks after the end of treatment. Furthermore, the clinical efficacy and safety indicators were compared between the two groups.

Results

A total of 76 participants consisting of 38 in each of the two groups were enrolled. The scores of each clinical symptom and sign, including sneezing, runny nose, stuffy nose, nasal itching, and turbinate edema, and the total scores decreased over time in both groups (all P<0.05); and no difference was found in the scores between the two groups (P>0.05). There was no statistically significant difference in the effective rates of the acupuncture group at 4 and 8 weeks after the start of treatment as well as at 12-week follow-up compared with those of the medication group (83.3% vs. 91.2%, and 94.4 % vs. 85.3%; and 80.6 % vs. 82.4%, all P>0.05). Experimental items including blood routine, urine routine, aspartate transaminase, alanine aminotransferase, urea nitrogen and creatinine were all in the normal reference ranges during the treatment in the acupuncture group.

Conclusions

Acupuncture therapy has a comparable effect to the medication treatment on patients with moderate to severe allergic rhinitis, and it is safe with no severe adverse effects.

     

温针灸对兔膝骨关节炎模型基质金属蛋白酶及组织形态学影响的实验研究

目的:观察温针灸对膝骨关节炎模型血清基质金属蛋白酶及软骨组织形态学的影响,探讨温针灸治疗膝骨关节炎在软骨代谢方面的作用机制。方法:将新西兰兔随机均分为空白组、模型组、温针灸组。采用膝关节前交叉韧带切断术制备膝骨关节炎模型,造模1周后温针灸患侧膝关节"犊鼻"、"后三里"穴2个疗程,采用ELISA法测定各组血清中MMP-1、MMP-3、TIMP-1的浓度,股骨内髁行HE染色。结果:模型组MMP-1浓度、MMP-1/TIMP-1比值均高于空白组(P﹤0.05),MMP-3浓度低于空白组(P﹤0.05),TIMP-1变化不明显(P﹥0.05),HE染色示明显的病理损伤;与模型组比较温针灸降低了MMP-1的浓度与MMP-1/TIMP-1之比值,升高MMP-3的浓度,差异有统计学意义(P﹤0.05);且改善了软骨病理损伤。结论:温针灸能够提高膝骨关节炎软骨的自身修复能力,其软骨保护作用可能是通过调节异常的MMP-1、MMP-3与MMP-1/TIMP-1比值而实现的。     

针刺联合西药治疗带状疱疹的临床观察及其对血浆P物质的影响

目的研究针刺联合西药疗法对带状疱疹患者皮损、神经痛及外周血浆P物质含量的影响。方法将60例入选患者随机分为两组。对照组给予西药治疗（抗病毒药物、营养神经药物及止痛药物）;试验组在对照组的基础上加用针刺疗法。采用止疱时间、完全结痂时间及皮损痊愈时间评估皮损恢复情况;用视觉模拟评分法（VAS）评估疼痛缓解情况;同时记录PHN的发生率;并测量治疗前后外周血浆P物质的含量。结果试验组止疱时间、完全结痂时间、皮损痊愈时间均比对照组短（P〈0.05）;两组治疗后的VAS指数及外周血浆P物质含量均较治疗前显著性下降（P〈0.01）;且试验组下降的更明显（P〈0.01）;同时试验组PHN发生率明显低于对照组（P〈0.05）。结论针刺联合西药疗法能加快带状疱疹患者皮损的恢复和疼痛的缓解,其作用机理可能与促进外周血浆P物质含量的下降有关。     

药饼灸治疗慢性呼吸系统疾病105例

目的：观察药饼灸治疗慢性呼吸系统疾病的临床疗效。方法：连续3年于每年三伏对105例慢性呼吸系统疾病的病人给予药饼灸治疗。结果：治愈20例，好转72例，无效13例，总有效率为87．62％。结论：药饼灸对慢性呼吸系统疾病有肯定的治疗效果。     

针刺治疗老年重症肺炎合并胃肠功能障碍的临床观察

目的:评价针刺治疗对老年重症肺炎患者胃肠功能的作用。方法:将64例重症肺炎患者随机分为对照组(31例)和针刺组(33例),观察其临床症状、胃肠激素、胃残留量(GRV)、腹腔内压力(IAP)和急性生理与慢性健康Ⅱ(APACHEⅡ)评分。结果:针刺组返流呕吐消失时间和肠鸣间恢复正常时间较对照组明显改善(P<0.05);与治疗前比较,针刺组治疗后GRV、APACHEⅡ评分下降(P<0.01),MOT增高,GAS和D-乳酸水平均显著降低(P<0.05,P<0.01);与对照组同期比较,针刺组IAP、APACHEⅡ评分、MOT、GAS、D-乳酸改善显著(P<0.05,P<0.01);总有效率明显高于对照组(P<0.05)。结论:针刺治疗能够有效地改善老年重症肺炎患者的胃肠道症状,减少胃储留及腹腔内压力水平,其改善胃肠功能机制可能与通过调节胃肠激素水平、改善胃肠屏障功能有关。     

“老十针”配合穴位注射治疗顽固性呃逆35例

1临床资料35例患者均为本院针灸科2009—06～2012—08门诊病人，男15例，女20例；年龄最小2l岁，最大89岁；病程最短3天，最长1年；胃肠道术后lO例、造影剂使用后7例、气胸后1例、尿毒症4例、脑血管病9例、肿瘤4例。对于青光眼、高血压控制不佳、癫痫等患者则不宜使用哌甲酯者，不纳入病例观察。     

背俞穴刺络拔罐结合针刺治疗急性湿疹35例

湿疹是由多种复杂的内、外因素引起的表皮及真皮浅层的炎症性皮肤病,具有多样性皮疹和渗出倾向,伴剧烈瘙痒,易反复发作,无传染性,西医认为与变态反应有一定关系。2011年7月—2013年12月笔者应用背俞穴刺络拔罐联合针刺治疗急性湿疹35例,疗效满意,现报道如下。     

背俞穴刺络拔罐结合针刺治疗急性湿疹35例临床疗效观察

目的：明确背俞穴刺络拔罐结合针刺对急性湿疹的治疗作用。方法：肺腧、膈腧点刺放血拔罐结合针刺腧穴治疗临床收集的35例急性湿疹患者，观察其疗效。结果：刺络拔罐结合针刺对急性湿疹总有效率为91.4%。结论：刺络拔罐结合针刺对急性湿疹疗效明确。