10 Gbit/s optical BPSK homodyne detection experiment with solitaryDFB laser diodes

Solitary DFB laser diodes with 174 kHz beat linewidth are applied to a 10 Gbit/s optical BPSK homodyne detection system for the first time: a sensitivity of -38.9 dBm was achieved. A three-electrode laser forms the local oscillator and is modulated with a partial push-pull scheme to improve its frequency response     

空调白色面板ABS材料光老化研究

采用家电行业常用的人工加速光老化实验方法,对目前空调面板常用的白色ABS材料进行了光老化研究,一方面比较了色母料和改性料方案的耐光老化性能,另一方面比较了常用光老化试验方法严酷程度.研究表明:改性料方案耐光老化性能优于色母料;采用氙灯光老化(X)、紫外光老化UVA(ZA)和紫外光老化UVB(ZB)等三种常用试验方法时,实验样品对光老化的响应程度依次为:UVB(ZB)测试＞UVA(ZA)测试＞氙灯(X)测试.     

Biased distribution of the branched-chain fatty acids in ceramides of vernix caseosa

The compositions of ester- and amide-linked fatty acids from ceramides of human vernix caseosa were described with emphasis on the distribution of the branched-chain fatty acid (BCFA). Two novel ceramides were isolated from vernix caseosa in the course of this study: the acylated type of esterified α-OH-hydroxyacid/sphingosine ceramide (Cer[EAS]) and nonacylated type of non-OH fatty acid/hydroxysphingosine ceramide (Cer[NH]). Their chemical structures were identified by nuclear magnetic resonance and chemical procedure. The Cer[EAS] was an acylceramide and consisted of the highest concentrations of ester- and amide-linked BCFA (62 and 67%, respectively). The iso- or anteiso-branching structures of the aliphatic chains were confirmed by the mass spectra of their picolinyl or pyrrolidide derivatives. As a whole, amide-linked fatty acids of ceramides 1–7 and Cer[NH] were normal types of straight-chain fatty acids with or without α- or ω-hydroxylation. The BCFA concentrations of amide-linked fatty acids in these ceramides (ceramides 1–7 and Cer[NH]) were low and less than 10%. The BCFA thus occurred exclusively in a novel acylceramide of Cer[EAS] in the vernix caseosa.     

Heavy oil sorption and recovery by using carbon fiber felts

On fibrous carbon materials, including activated carbon fibers, sorption capacity for heavy oils, less viscous A-grade and more viscous C-grade, was determined. Sorption capacity depended strongly on their bulk density; the correlation was the same as that found previously on exfoliated graphite and carbonized fir fibers. On carbon fiber felts, excellent recycling performance was observed, though sorption capacity was not so high as on exfoliated graphite and carbonized fir fibers. By filtration under suction, about 90% of sorbed A-grade heavy oil could be recovered and no decrease in sorption capacity was detected even after eight cycles. By washing with solvents, n-hexane for A- and C-grade oils and A-grade oil for C-grade oil, almost 100% recovery with no marked reduction in sorption capacity was found for each cycle. For the felts of PAN-based carbon fibers, rather severe operations for oil recovery, centrifugation and squeezing with twisting, could be applied without pronounced decreases in sorption capacity and recovery ratio.     

Preconditioned iterative solver on the coarsest level of a multi-grid method for high frequency time harmonic electromagnetic field analyses

A multi-grid method is one of the most powerful linear solvers for finite element electromagnetic field analysis. However, as the discretized model has recently been enlarged, a solution process for a linear system arising on the coarsest level tends to be problematic in a complete multi-grid solution process. Whereas a linear system on the coarsest level is generally solved by a direct solver, we solve it here by means of an iterative solver to reduce the memory requirements. Since a conventional preconditioning technique is not effective for such a linear system, we introduce preconditioning techniques based on Arnold, Falk, and Winther’s and on Hiptmair’s smoothers. Numerical tests show that the newly installed preconditioning technique greatly improves the convergence rate.     

Ferroptosis Modulation: Potential Therapeutic Target for Glioblastoma Treatment

Glioblastoma multiforme is a lethal disease and represents the most common and severe type of glioma. Drug resistance and the evasion of cell death are the main characteristics of its malignancy, leading to a high percentage of disease recurrence and the patients’ low survival rate. Exploiting the modulation of cell death mechanisms could be an important strategy to prevent tumor development and reverse the high mortality and morbidity rates in glioblastoma patients. Ferroptosis is a recently described type of cell death, which is characterized by iron accumulation, high levels of polyunsaturated fatty acid (PUFA)-containing phospholipids, and deficiency in lipid peroxidation repair. Several studies have demonstrated that ferroptosis has a potential role in cancer treatment and could be a promising approach for glioblastoma patients. Thus, here, we present an overview of the mechanisms of the iron-dependent cell death and summarize the current findings of ferroptosis modulation on glioblastoma including its non-canonical pathway. Moreover, we focused on new ferroptosis-inducing compounds for glioma treatment, and we highlight the key ferroptosis-related genes to glioma prognosis, which could be further explored. Thereby, understanding how to trigger ferroptosis in glioblastoma may provide promising pharmacological targets and indicate new therapeutic approaches to increase the survival of glioblastoma patients.     

基于椭圆曲线密码体制的投票协议

本文设计了一种基于椭圆曲线密码体制的投票协议,该协议的特点是能够使投票者在计算机网络上进行无记名投票,并可以有效地抵制各种欺骗行为,从而使安全选举成为可能。     

Characterization of the Secretome of a Specific Cell Expressing Mutant Methionyl-tRNA Synthetase in Co-Culture Using Click Chemistry

Co-culture system, in which two or more distinct cell types are cultured together, is advantageous in that it can mimic the environment of the in vivo niche of the cells. In this study, we presented a strategy to analyze the secretome of a specific cell type under the co-culture condition in serum-supplemented media. For the cell-specific secretome analysis, we expressed the mouse mutant methionyl-tRNA synthetase for the incorporation of the non-canonical amino acid, azidonorleucine into the newly synthesized proteins in cells of which the secretome is targeted. The azidonorleucine-tagged secretome could be enriched, based on click chemistry, and distinguished from any other contaminating proteins, either from the cell culture media or the other cells co-cultured with the cells of interest. In order to have more reliable true-positive identifications of cell-specific secretory bodies, we established criteria to exclude any identified human peptide matched to bovine proteins. As a result, we identified a maximum of 719 secreted proteins in the secretome analysis under this co-culture condition. Last, we applied this platform to profile the secretome of mesenchymal stem cells and predicted its therapeutic potential on osteoarthritis based on secretome analysis.     

Olympics and Urban Legacy in Sydney: Urban Transformations and Real Estate a Decade after the Games

The Olympic Games (OG) are an opportunity for cities to display themselves on the world stage. Cities from developed and developing countries present themselves to hold the Games, always with a double intention: to promote itself in the global arena and use this opportunity to stimulate urban changes. However, there are very few studies that analyze the urban legacy of the OG for the host cities, probably because it takes years for an urban legacy to become established, and when the time is right to analyze this legacy other OG are on the agenda. The aim of this paper is to analyze the urban legacy left by the 2000 OG in Sydney. Sydney has been chosen for this analysis because, as there have been no other major development projects for the Homebush Bay region since the 2000 OG, the impact of the Games can be measured, specifically regarding physical transformations, discussing what their real urban legacy is.