Application of EPR-MOGA in computing the liquefaction-induced settlement of a building subjected to seismic shake

Accurate prediction of the liquefaction-induced settlement (\({S}_{\mathrm{lc}}\)) is an essential requirement for a good design of buildings resting on liquefiable ground and subjected to seismic shake. However, prediction of the \({S}_{\mathrm{lc}}\) is not straightforward process and it requires advanced soil models and calibrated soil parameters that are not readily available for designers/practitioners. In addition, the available empirical models to estimate the \({S}_{\mathrm{lc}}\) have been developed using either classical regression analysis or multivariate adaptive regression splines and such techniques produce complicated models. Also, these empirical models have been developed utilizing results of numerical modelling. To overcome these limitations, novel model has been developed in this paper utilizing robust regression analysis driven by artificial intelligence called the evolutionary polynomial regression analysis. The new model has been developed using centrifuge results (real laboratory measurements) and can be easily used to accurately estimate the liquefaction induced settlement. The developed model scored a mean absolute error, root mean square error, mean, standard deviation of the predicted to measured values, coefficient of determination, \(a20 - \mathrm{index}\), and EPR coefficient of determination of 2.12 cm, 2.84 cm, 1.06, 0.19, 0.98, 0.77, and 97%, respectively, for the learning data and 1.73 cm, 3.31 cm, 0.99, 0.17, 0.97, 0.75, and 97%, respectively, for the examination data. The developed model has also been used in a parametric study to provide an insight into the sensitivity of the \({S}_{\mathrm{lc}}\) to the foundation width, building height, pressure applied on the foundation, thickness and relative density of the liquefiable layer, and earthquake intensity. The results obtained from the parametric study are reasonable and in agreement with previous studies in the literature. Thus, the developed model can be employed to optimize designs and to reduce design costs as it does not require complicated analyses and/or expensive computational facilities.

     

Mechanical behavior of 30–50 nm thick aluminum films under uniaxial tension

We present uniaxial tensile test results for 30–50 nm thick freestanding aluminum films. Young’s modulus and ductility were found to decrease monotonically with grain size. Reverse Hall–Petch behavior was observed with no appreciable room temperature creep. Non-linear elasticity with small irreversible deformation was observed for 50 nm thick specimens.     

Enteric viral infections of calves and passive immunity

At least eight viruses have been identified, four within the last 5 yr, that produce diarrhea and pathological intestinal lesions in experimentally inoculated calves. Coronavirus and rotavirus frequently are associated with the neonatal calf diarrhea syndrome, but the etiologic role of the newly identified viruses is undefined. All diarrheal viruses replicate within small intestinal epithelial cells, resulting in variable degrees of villous atrophy. Immunity against these viral infections, therefore, must be directed toward protection of the susceptible intestinal epithelial cells. Because most of these viral infections occur in calves less than 3 wk of age, passive lactogenic immunity within the gut lumen plays an important role in protection. This report reviews methods of boosting rotavirus antibody responses in bovine mammary secretions and analyses of passive and active immunity in calves supplemented with colostrum and challenged by rotavirus. Results indicate rotavirus immunoglobulin G1 antibodies in colostrum and milk were elevated after intramuscular and intramammary vaccination of pregnant cows with an Ohio Agricultural Research and Development Center rotavirus vaccine but not after intramuscular immunization with a commercial rota-coronavirus vaccine. Feeding colostrum from intramuscular plus intramammary immunized cows to newborn calves challenged by rotavirus prevented diarrhea and shedding of rotavirus.     

Vortex structure in high-T c ceramic superconductors

We consider penetration of magnetic flux in the rare earth ceramic superconductors within the framework of a generalized Ginzburg-Landau theory, based on the coexistence of antiferromagnetism and superconductivity. We study vortex structure produced for a magnetic field close to . We make a new prediction that may serve to test the theory experimentally.     

Interactive Evolutionary Multi-Objective Optimization Algorithm Using Cone Dominance

As the number of objectives increases, the performance of the Pareto dominance-based Evolutionary Multi-objective Optimization (EMO) algorithms such as NSGA-II, SPEA2 severely deteriorates due to the drastic increase in the Pareto-incomparable solutions. We propose a sorting method which classifies these incomparable solutions into several ordered classes by using the decision maker's (DM) preference information. This is accomplished by designing an interactive evolutionary algorithm and constructing convex cones. This method allows the DMs to drive the search process toward a preferred region of the Pareto optimal front. The performance of the proposed algorithm is assessed for two, three, and four-objective knapsack problems. The results demonstrate the algorithm's ability to converge to the most preferred point. The evaluation and comparison of the results indicate that the proposed approach gives better solutions than that of NSGA-II. In addition, the approach is more efficient compared to NSGA-II in terms of the number of generations required to reach the preferred point.     

Heat exchanger network synthesis with detailed exchanger designs: Part 1. A discretized differential algebraic equation model for shell and tube heat exchanger design

A new method for the detailed design of shell and tube heat exchangers is presented through the formulation of coupled differential heat equations, along with algebraic equations for design variables. Heat exchanger design components (tube passes, baffles, and shells) are used to discretize the differential equations and are solved simultaneously with the algebraic design equations. The coupled differential algebraic equation (DAE) system is suitable for numerical optimization as it replaces the nonsmooth log mean temperature difference (LMTD) term. Discrete decisions regarding the number of shells, fluid allocation, tube sizes, and number of baffles are determined by solving an LMTD-based method iteratively. The resulting heat exchanger topology is then used to discretize the detailed DAE model, which is solved as a nonlinear programming model to obtain the detailed exchanger design by minimizing an economic objective function through varying the tube length. The DAE model also provides the stream temperature profiles inside the exchanger simultaneously with the detailed design. It is observed that the DAE model results are almost equal to the LMTD-based design model for one-shell heat exchangers with constant stream properties but shows significant differences when streams properties are allowed to vary with temperature or the number of shells are increased. The accuracy of the solutions and the required computational costs show that the model is well suited for solving heat exchanger network synthesis problems combined with detailed exchanger designs, which is demonstrated in Part 2 of the paper.     

Microfluidic continuous magnetophoretic protein separation using nanoparticle aggregates

We demonstrate a microfluidic continuous-flow protein separation process in which silica-coated superparamagnetic nanoparticles interact preferentially with hemoglobin in a mixture with bovine serum albumin, and the resulting hemoglobin-nanoparticle aggregates are recovered online using magnetophoresis. We present detailed modeling and analysis of this process yielding quantitative estimates of the recovery of both proteins, validated by experiments. While several previous studies utilize an average particle size in modeling magnetophoretic particle trajectories or process design, in this study we emphasize the importance of accounting for particle size distributions in calculating particle recovery, and therefore in estimating separation efficiency. We combine experimentally measured size distributions of protein-nanoparticle aggregates with simulations of particle trajectories and provide a simple analytical method to calculate the efficiency of separation at various flow speeds, which fully accounts for heterogeneity in particle sizes. Our method can potentially be used for affinity based biomolecular separations at both analytical and preparative scales by exploiting well-established techniques to functionalize nanoparticle surfaces with selective ligands. Further, the modeling methodology presented here may be applied to provide better estimates of particle recovery in a broad range of magnetophoretic separation processes involving heterogeneity in particle sizes.     

Microscale materials testing using MEMS actuators

Small size scale and high resolutions in force and displacement measurements make MEMS actuators appropriate for micromechanical testing. In this paper, for the first time, we present methodologies for uniaxial tensile and cantilever bending testing of both micrometer- and submicrometer-scale freestanding specimens using MEMS actuators. We also introduce dry fabrication processes for the specimens. The methodologies allow freestanding single or multilayered thin-film specimens to be fabricated separately from the MEMS actuators. For the uniaxial tension test, tensile forces are applied by lateral comb drive actuators capable of generating a total load of 383 μN at 40 V with resolutions on the order of 3 nN. A similar actuator is used in the bending test, with load resolution of 58 nN and spring constant of 0.78 N/m. The tensile testing methodology is demonstrated with the testing of a 110-nm-thick freestanding aluminum specimen. The cantilever bending experiment is performed on a 100-nm-thick aluminum specimen. The experimental setups can be mounted in a SEM (and also in a TEM after modifications for tensile testing) for in situ observation of materials behavior under different environmental conditions. Remarkable strengthening is observed in all the specimens tested compared to their bulk counterparts in both tensile and bending experiments. Experimental results highlight the potential of MEMS actuators as a new tool for materials research     

Mechanical properties and microstructure of rolled and electrodeposited thin copper foil

Commercial grade rolled and electrodeposited copper foils from Japan and China were selected, and their mechanical properties and microstructure were investigated. It was observed that there are notable differences in fracture strength, elongation at break and hydrophilicity between rolled and electrodeposited copper foils. The rolled copper foils have higher tensile strength, lower ductility and larger static contact angle than electrodeposited copper foils. The rolled copper foils contain a β-fiber texture, and the electrodeposited copper foils have random crystalline orientations. It was also observed that the rolled foils have packed grains, and electrodeposited foils have equiaxial grains. The uniform fine grain size and a few substructures of Japanese electrodeposited foils are major reasons for their higher elongation.