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1.
Jin B. Ong Osama K. Eyada PhD PE Abu S. Masud PhD PE 《Computers & Industrial Engineering》1989,17(1-4):85-89
This paper presents a Knowledge-based system (KBS) developed to allow users, who may not be knowledgeable about sensors, to select sensors suitable for their specific needs. The KBS runs on a micro-computer. The selection criteria are user specified and are based on the desired measurement parameters. The system output includes all of the operational and dimensional parameters of the recommended sensor, price, and vendor information. 相似文献
2.
Hypothermia induced by surface cooling has shown to protect vulnerable regions of the brain during an ischemic insult. This study evaluated the neuroprotective efficacy of neurotensin, a potent hypothermic agent, using a 5-min carotid occlusion procedure in the gerbil. In Experiment 1, the dose-response and time course of neurotensin-induced hypothermia were evaluated (n = 5/dose). Central infusion of 10, 20, and 30 micrograms neurotensin were found to significantly decrease core body temperature of conscious gerbils within 30 min of administration. In Experiment 2, gerbils pretreated with 30 micrograms neurotensin were permitted to become hypothermic or were maintained at 37 degrees-38 degrees C (rectal) during ischemic insult. Other gerbils were pretreated with peptide vehicle prior to ischemic insult (at 37 degrees -38 degrees C) or underwent a sham procedure (n = 6/condition). At 24 h after surgery, gerbils were tested for increased locomotor activity in an open-field apparatus. Gerbils pretreated with peptide vehicle or neurotensin and maintained at 37 degrees-38 degrees C during ischemia had significantly higher activity levels compared to the other treated groups. In contrast, gerbils made hypothermic with neurotensin exhibited activity levels similar to sham gerbils. Histological assessment revealed that neurotensin-induced hypothermia protected the CA1 region from ischemic damage. 相似文献
3.
4.
An optical nondestructive strain measurement technique was performed to analyze the mechanical deformation induced by an electrical field within the insulating materials. Poly(ethylene naphthalene 2,6‐dicarboxylate) (PEN) films were then subjected to constant electrical fields right up to their electrical breakdown. The experimental technique made it possible to follow the various stages of the mechanical behavior of PEN in real time. The final breakdown occurred in the observation zone and the related mechanical deformation was captured. A “margarita” structure was observed with a hole at the center. The experimental results indicated that the level of the induced‐mechanical deformations depended on the local environment. We defined two different zones representing the inside and the outside of the damaged area. The induced‐deformations were larger in the damaged zone. It was also observed that deformations increased when the sample had a lower degree of crystallinity. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008 相似文献
5.
Kaslow Nadine J.; Rubin Nancy J.; Forrest Linda; Elman Nancy S.; Van Horne Barbara A.; Jacobs Sue C.; Huprich Steven K.; Benton Sherry A.; Pantesco Victor F.; Dollinger Stephen J.; Grus Catherine L.; Behnke Stephen H.; Miller David S. Shen; Shealy Craig N.; Mintz Laurie B.; Schwartz-Mette Rebecca; Van Sickle Kristi; Thorn Beverly E. 《Canadian Metallurgical Quarterly》2007,38(5):479
Working collaboratively, psychologist educators and trainers at the doctoral, internship, and postdoctoral levels; credentialers; practitioners; and students offer 8 proposals for psychologists to consider in recognizing, assessing, and intervening with problems of professional competence in students and practicing professionals. In the proposals, the authors address the following topics: definitions and categories; preparing the system; self-assessment; remediation; diversity; communication across various levels of the system; confidentiality; and ethical, regulatory, and legal underpinnings. They also propose future directions for the assessment of problems in professional competence in both students and practicing psychologists. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
6.
The combined generation of heat and power (cogeneration) is praised by many as a technique for reducing the emissions of CO2 in industrialized nations. This is generally true but not always. In this article we discuss the impact of some major variables on the CO2 emission reduction capacity of cogeneration. Two sets of variables are predominant: the characteristics of the CHP process and the composition of the electricity generation sector. We highlight the interaction between the two sets of variables with the help of diagrams. 相似文献
7.
Abu Avi Lupa Israel 《AEUE-International Journal of Electronics and Communications》2005,59(5):307-310
This letter presents a general analysis of time jitter in sigma-delta synthesizer. One of the practical applications of 1-bit sigma-delta systems is a generation of high-resolution local oscillator (LO) signals. In order to generate LO signals, one may use a single-bit sigma-delta technique to encode sine waves. Today, direct generation of high-frequency sine wave using a clock with higher frequency, is possible. In this letter, we will analyze different LO signal generators and develop a practical way of computation to decide how to choose the best configuration under minimum degradation of signal-to-noise ratio (SNR) at the output. 相似文献
8.
A 0.3% Au/Al2O3 catalyst prepared by the incipient wetness (IW) method was investigated in the continuous-flow liquid-phase glucose oxidation. Therefore, a continuous stirred tank reactor (CSTR) system equipped with an ultrasonic separator was used. The continuous-flow glucose oxidation was carried out at 40 °C, pH 9 and 1 bar oxygen partial pressure. Residence time and glucose concentration were varied. The IW gold catalyst showed very high activity and selectivity to gluconic acid within its 110 days of operation and, thus, an excellent long-term stability. Even after severe microbial contaminations of the catalyst, its activity could be completely restored by in situ regeneration with 2-propanol. 相似文献
9.
Nadine Kretschmer Antje Hufner Christin Durchschein Katrin Popodi Beate Rinner Birgit Lohberger Rudolf Bauer 《International journal of molecular sciences》2021,22(5)
Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment is challenging, and survival rates are very low. In previous studies, we showed that the constituents of the roots of Onosma paniculata as well as a synthetic derivative of the most active constituent showed promising results in metastatic melanoma cell lines. In the current study, we address the question whether we can generate further derivatives with optimized activity by synthesis. Therefore, we prepared 31, mainly novel shikonin derivatives and screened them in different melanoma cell lines (WM9, WM164, and MUG-Mel2 cells) using the XTT viability assay. We identified (R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl 2-cyclopropyl-2-oxoacetate as a novel derivative with even higher activity. Furthermore, pharmacological investigations including the ApoToxGloTM Triplex assay, LDH assay, and cell cycle measurements revealed that this compound induced apoptosis and reduced cells in the G1 phase accompanied by an increase of cells in the G2/M phase. Moreover, it showed hardly any effects on the cell membrane integrity. However, it also exhibited cytotoxicity against non-tumorigenic cells. Nevertheless, in summary, we could show that shikonin derivatives might be promising drug leads in the treatment of melanoma. 相似文献
10.
Temperature-dependent diffusion coefficient of soluble substances during ethanol extraction of clove
San Myint Wan Ramli Wan Daud Abu Bakar Mohamad Abdul Amir H. Kadhum 《Journal of the American Oil Chemists' Society》1996,73(5):603-610
The temperature dependence of the diffusion coefficient of ethanol-soluble substances from ground cloves (particle size 250
μm) during extraction was estimated by fitting batch extraction data at several temperatures (27.8, 40, 50, and 60°C) to a
previously developed mass transfer model. The model was based on spherical geometry of particles. Nonlinear regression analysis
was used to develop an equation that describes the diffusivity as a function of temperature. The temperature dependence ofD
A
was of the Arrhenius type. 相似文献