全文获取类型
收费全文 | 7131篇 |
免费 | 580篇 |
国内免费 | 38篇 |
学科分类
医药卫生 | 7749篇 |
出版年
2023年 | 62篇 |
2022年 | 114篇 |
2021年 | 201篇 |
2020年 | 112篇 |
2019年 | 189篇 |
2018年 | 205篇 |
2017年 | 127篇 |
2016年 | 175篇 |
2015年 | 203篇 |
2014年 | 266篇 |
2013年 | 379篇 |
2012年 | 538篇 |
2011年 | 499篇 |
2010年 | 334篇 |
2009年 | 257篇 |
2008年 | 428篇 |
2007年 | 461篇 |
2006年 | 403篇 |
2005年 | 363篇 |
2004年 | 369篇 |
2003年 | 337篇 |
2002年 | 294篇 |
2001年 | 56篇 |
2000年 | 36篇 |
1999年 | 80篇 |
1998年 | 142篇 |
1997年 | 120篇 |
1996年 | 103篇 |
1995年 | 80篇 |
1994年 | 57篇 |
1993年 | 66篇 |
1992年 | 29篇 |
1991年 | 37篇 |
1990年 | 36篇 |
1989年 | 65篇 |
1988年 | 51篇 |
1987年 | 41篇 |
1986年 | 24篇 |
1985年 | 41篇 |
1984年 | 18篇 |
1983年 | 22篇 |
1982年 | 31篇 |
1981年 | 27篇 |
1980年 | 23篇 |
1979年 | 18篇 |
1978年 | 25篇 |
1977年 | 18篇 |
1976年 | 17篇 |
1975年 | 13篇 |
1969年 | 11篇 |
排序方式: 共有7749条查询结果,搜索用时 0 毫秒
1.
2.
3.
Pyomyositis: characteristics at CT and MR imaging 总被引:9,自引:0,他引:9
4.
5.
D De AJ Kanwar S Handa 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):853-859
BACKGROUND: Diagnosis of atopic dermatitis (AD) depends on clinical features because no definitive diagnostic test exists. Criteria proposed by Hanifin and Rajka (Acta Derm Venereol (Stockh) 1980; Suppl 92: 44-47) were acceptable for hospital-based studies but were found not to be suitable for field studies. A UK working party formulated clinical diagnostic criteria that could be used in both hospital and epidemiological settings. Validation studies of the criteria showed widely variable results, probably due to different clinical settings and ethnicity. AIM AND OBJECTIVE: This study was undertaken to validate Hanifin and Rajka's criteria and to assess the comparative efficacy of their criteria and the UK working party's diagnostic criteria in the diagnosis of AD in a hospital setting in North India. SUBJECTS AND METHODS: This study serially included 101 patients with AD and 48 controls of paediatric age group. The study period was from July 2003 to December 2004. RESULTS: Hanifin and Rajka's criteria (sensitivity 96%, specificity 93.75%, positive predictive value 97% (PPV) and negative predictive value (NPV) 91.84%) had a statistical advantage over the UK working party's diagnostic criteria (sensitivity 86%, specificity 95.83%, PPV 97.75% and NPV 76.67%), with a P-value < 0.005. 相似文献
6.
SUMMARY Impotence is a common symptom which can cause considerable distress to both the sufferer and his partner. The use of pharmacotherapy to improve erectile function will continue to increase as safe and effective drugs are developed. However, restoring erectile function should not be the only treatment objective. It is also essential to address personal and emotional factors in the sufferer, conflicts in his relationship with his partner, and sexual problems in his partner, all of which may be instrumental in causing or maintaining the presenting impotence. We advocate a combined approach with appropriate medical treatment and sex and couple therapy 相似文献
7.
8.
9.
10.
Ying Qian Pedram Hamrah Florence Boisgerault Satoru Yamagami Sudhir Vora Gilles Benichou M Reza Dana 《Journal of interferon & cytokine research》2002,22(12):1217-1225
This study aimed to determine the effects of anti-CD154 on T cell cytokine profiles and ocular chemokine gene expression after high-risk corneal transplantation and to specifically determine if CD154 blockade is associated with a switch from a Th1 to a Th2 alloimmune response. Mice were used as recipients of syngeneic or multiple minor H or MHC antigen-mismatched corneal grafts. Recipient beds were neovascularized (high-risk). Hosts were randomized to receive either anti-CD154 antibody or control immunoglobulin (Ig) perioperatively. Two weeks after corneal transplantation, allospecific delayed-type hypersensitivity (DTH) was evaluated. Frequencies of interferon-gamma (IFN-gamma)-, interleukin-2 (IL-2)-, IL-4-, and IL-5-secreting T cells in the hosts were measured by enzyme-linked immunospot (ELISPOT) assay. Ocular chemokine gene expression in anti-CD154-treated and control hamster Ig-treated groups was determined using a multiprobe ribonuclease protection assay (RPA). Leukocyte infiltration of corneal grafts was evaluated microscopically. Anti-CD154-treated mice did not exhibit allospecific DTH. The frequencies of Th1 cytokine-producing but not Th2 cytokine-producing T cells were significantly reduced in anti-CD154-treated hosts. Postoperative mRNA levels of RANTES and macrophage inflammatory protein-1beta (MIP-1beta) in anti-CD154-treated eyes were substantially suppressed compared with hamster Ig-treated controls. Leukocyte infiltration was profoundly suppressed in grafts of anti-CD154-treated hosts. These data demonstrate that blockade of the CD40-CD154 costimulatory pathway after corneal transplantation inhibits Th1-mediated responses but does not induce a switch to a Th2-specific response. In addition, anti-CD154 therapy suppresses ocular chemokine gene expression and leukocytic infiltration into allografts. 相似文献