生物材料静态血清接触对总补体溶血活性(CH50)影响的实验研究

机体在抗原的作用下产生一系列免疫反应,血清中总补体含量的变化可反映补体活化及免疫反应程度.本文参照有关标准方法,选择八种生物材料,与血清进行体外培养,在不同时间内测定总补体溶血活性(CH50),探讨生物材料免疫反应.试验结果表明,八种材料接触血清测得CH50值均低于对照组,但每种材料降低程度有所不同,CA和PETF降低最明显,CH50定值均＜40单位@ml-1,而对照组为80单位@ml-1.PP和BC材料的CH50值与对照组结果比基本一致.PETF和PES两种材料接触不同时间(30min,90min,120min)随时间的延长逐渐降低,而PETF降低较明显.该研究初步表明CA和PETF材料具有活化补体,降低CH50值,提高免疫反应的作用.     

创伤性胰兼的诊治探讨

创伤性胰瘘是胰腺损伤后最常见的严重并发症 ,其发病率较高 ,约为 1 5%～ 30 % [1 ]。本院自 1 985- 0 3～ 2 0 0 1 - 0 3共收治创伤性胰瘘患者 2 5例 ,占胰腺损伤患者的 2 6 .9% ( 2 5/93) ,现报告如下。1　对象和方法1 .1　对象　本组 2 5例 ,男 1 8例 ,女 7例 ,年龄 8～ 6 2岁。闭合性胰腺损伤 1 7例 ,开放性胰腺损伤 6例 ,医源性损伤 2例。胰外瘘 2 1例 ,胰内瘘 (假性胰腺囊肿 ) 4例 (囊肿直径约 3.5～ 1 7cm不等 )。胰瘘的部位 :胰头部 8例 ,胰体部 1 2例 ,胰尾部 5例。胰瘘的原因有误诊、漏诊胰腺外伤 5例 ,胰腺创面缝合不恰当 ,胰管…     

中国内地首例输入性甲型H1N1流感病例诊断处置流程分析

Objective The patient started from St. Louis (U. S.), and reached Chengdu (China) after 3 days of flight(St. Louis- Tokyo- Beijing - Chengdu). The patient felt unwell, so he and the two relatives took a taxi to the Emergency Center of Sichuan Provincial People' s Hospital for treatment. The epidemiological survey showed that, the patient had been living in the University of Missouri in the United States, no pigs died locally, there were no markets for the living pigs, farmers markets, farms, and slaughterhouses, and he hadn't contact with pigs. But 4 days before the onset, he closely contacted with a schoolmate, who had cold symptoms. The pa-tient had never been to virus laboratory 7 days before the onset. Clinical examinations showed that, the patient had a fever (37.8 ～ 38.8℃), WBC 7.9×10-9 L-1, N 5.475 × 10-9 L-1, L 19.5% ;the chest X-ray shewed that texture increased and the heart shadow augmented on both lungs; the result of throat swab culture was negative. The result of virus nucleic aeid detected by Sichnan Provincial Center for Disease Control showed H1N1 influenza virus, suspected. Sichuan Province Health organization organized experts on the prevention and control of H1N1 influenza for consultation, and the patient was diagnosed as the first suspected H1N1 influenza case in mainland China based on the epidemiological investigation, symptoms and signs of the patient, the results of laboratory ex-amination, and the result of virus test. Confirmed by the experts from Chinese center for disease control and pre-vention and The Ministry of Health of the People's Republic of China, the patient was diagnosed as the first H1N1 influenza case in mainland China.     

中国内地首例输入性甲型H1N1流感病例诊断处置流程分析

Objective The patient started from St. Louis (U. S.), and reached Chengdu (China) after 3 days of flight(St. Louis- Tokyo- Beijing - Chengdu). The patient felt unwell, so he and the two relatives took a taxi to the Emergency Center of Sichuan Provincial People' s Hospital for treatment. The epidemiological survey showed that, the patient had been living in the University of Missouri in the United States, no pigs died locally, there were no markets for the living pigs, farmers markets, farms, and slaughterhouses, and he hadn't contact with pigs. But 4 days before the onset, he closely contacted with a schoolmate, who had cold symptoms. The pa-tient had never been to virus laboratory 7 days before the onset. Clinical examinations showed that, the patient had a fever (37.8 ～ 38.8℃), WBC 7.9×10-9 L-1, N 5.475 × 10-9 L-1, L 19.5% ;the chest X-ray shewed that texture increased and the heart shadow augmented on both lungs; the result of throat swab culture was negative. The result of virus nucleic aeid detected by Sichnan Provincial Center for Disease Control showed H1N1 influenza virus, suspected. Sichuan Province Health organization organized experts on the prevention and control of H1N1 influenza for consultation, and the patient was diagnosed as the first suspected H1N1 influenza case in mainland China based on the epidemiological investigation, symptoms and signs of the patient, the results of laboratory ex-amination, and the result of virus test. Confirmed by the experts from Chinese center for disease control and pre-vention and The Ministry of Health of the People's Republic of China, the patient was diagnosed as the first H1N1 influenza case in mainland China.     

个体化肺结节三维重建模拟手术在胸腔镜肺段切除中的应用

目的探讨个体化肺结节三维重建模拟手术在胸腔镜肺段切除中的应用价值。方法 2018年12月～2019年12月接受手术治疗的肺结节病人60例,随机分为三维重建模拟手术组和非三维重建模拟手术组,每组各30例。比较两组围手术期相关指标的差异。结果两组均顺利完成胸腔镜下肺段切除术;三维重建模拟手术组术前与术中吻合率分别为:结节部位100%,靶段血管96.67%,靶段支气管96.42%;三维重建模拟手术组的手术时间、术中出血量、引流管留置时间、术后总引流量以及术后住院时间均低于非三维重建模拟手术组,差异有统计学意义(P0.05),两组术中清扫淋巴结个数与术后并发症发生率比较,差异无统计学意义(P0.05)。结论肺结节基于三维重建个体化胸腔镜解剖性肺段切除术安全有效,较常规手术更具临床应用价值。     

引导型食管插管治疗颈胸段食管癌10例

１９８９年以来，笔者对部分颈、胸段食管癌患者采取以引导型食管插管作为拔脱器，行非开胸食管内翻拔脱术治疗食管癌，共完成手术病例１０例，取得较满意的效果。１资料与方法１．１一般资料男６例，女４例；年龄４１～７２岁。病变范围１～４ｃｍ。颈段食管癌６例，上胸...     

液体平衡与血液脑钠肽浓度的变化

目的 研究危重患者液体平衡与血液脑钠肽浓度的变化是否相关.方法 采集2012年5月～2013年5月收入我科的165位危重患者的BNP检查数据,记录患者对应时间段的名义出量和入量.结果 危重患者的液体平衡与血液脑钠肽浓度变化之间仅存在微弱的相关性,r=0.149,P=0.001（Pearson correlation,2-tailed）.结论 液体平衡对容量负荷/BNP水平的影响是复杂的,液体治疗时应该考虑到这种复杂性.     

静脉注射6%羟乙基淀粉130/0.4和呋塞米治疗急性胰腺炎的初步研究

目的观察静脉输注6%羟乙基淀粉130/0.4（万汶）和静脉推注呋塞米（速尿）对急性胰腺炎转归的影响。方法入院当天即给予患者万汶静脉输注（成人通常为1000～2000ml）,同时静脉推注呋塞米,力求作到出入量基本平衡;入院第2天开始逐渐减少万汶用量。结果48例急性胰腺炎患者（Ranson评分≥3分者35%,Balthazar CT评分≥D或E者48%）,胰腺局部并发症和全身并发症仅为6%和4%,胰腺手术率为4%,1个月病死率为2%。结论静脉输注万汶和静脉推注呋塞米可改善急性胰腺炎的转归。     

2490名中老年干部钙化性主动脉瓣病的患病情况及超声心动图分析

本文分析了在2490名中老年干部中经超声心动图诊断的104例钙化性主动脉瓣病的超声心动图表现。发现其患病率随年龄增长成倍数递增,男性多于女性。该病不仅可以引起众所周知的AS,也可引起AI,以无冠瓣受累最多。轻—中度CAS及CAI尚不足以引起心脏解剖结构的明显改变,左室收缩功能也保持正常,但舒张功能却发生障碍。     

地震伤并发挤压综合征的救治分析

目的 探讨地震后发生挤压综合征的危险因素和治疗措施.方法在325例地震伤患者中,有35例并发挤压综合征,按其性别、年龄、伤后就诊时间、治疗过程及预后进行比较分析.结果 获救时间、诊治延误及年龄均是挤压综合征发生的高危因素.35例地震伤并发挤压综合征患者均行彻底切开减压,6例痊愈,2例遗留功能障碍,27例截肢.结论 对地震伤后挤压综合征伤情高度重视和准确判断,早期诊断,及时充分减压,是对地震伤并发挤压综合征最主要的预防与治疗措施.