The transjugular stent implantation for the treatment of malignant portal and hepatic vein obstruction in cancer patients

BACKGROUND: The increase in portal vascular resistance is a significant complication of metastatic disease to the liver or locally advanced cancer, e.g., biliary cancer. PATIENTS AND METHODS: This paper describes the successful palliative treatment of two cancer patients with portal hypertension presenting with the symptoms of tense ascites, mesenteric congestion, and severe variceal bleeding. By creating a stenttract between a hepatic vein and a main branch of the portal vein and/or by placing an extendable stent into the portal vein, the transjugular intrahepatic portosystemic stent-shunt (TIPS) technique was used to decompress the portovascular system. RESULTS: The TIPS-technique offers a new, safe and effective palliation for malignant portal hypertension. In both patients, the symptoms of the portal hypertension disappeared after the procedure. This was accompanied by a significant improvement of the patients performance status allowing an early ambulation. CONCLUSION: Our findings demonstrate the feasibility and effectiveness of the TIPS procedure as a minimal invasive treatment for portal vein decompression in selected tumor patients.     

0.27-dB/km attenuation achieved by MSP preform process [opticalfibers]

Mechanically shaped preforms (MSP) have been demonstrated to combine economic non-CVD (chemical vapor deposition) processing and low loss, with a published value of 0.63 dB/km and a size of 30 fkm/preform. Improved processing is proposed which results in a minimum loss of 0.27 dB/km at 1550 nm. Preforms capable of yielding 150 fkm have been produced. Reboiling during preform stretching and fiber pulling is identified as the last remaining problem of the process     

Variable cross-resistance to Cry11B from Bacillus thuringiensis subsp. jegathesan in Culex quinquefasciatus (Diptera: Culicidae) resistant to single or multiple toxins of Bacillus thuringiensis subsp. israelensis

A novel mosquitocidal bacterium, Bacillus thuringiensis subsp. jegathesan, and one of its toxins, Cry11B, in a recombinant B. thuringiensis strain were evaluated for cross-resistance with strains of the mosquito Culex quinquefasciatus that are resistant to single and multiple toxins of Bacillus thuringiensis subsp. israelensis. The levels of cross-resistance (resistance ratios [RR]) at concentrations which caused 95% mortality (LC95) between B. thuringiensis subsp. jegathesan and the different B. thuringiensis subsp. israelensis-resistant mosquito strains were low, ranging from 2.3 to 5.1. However, the levels of cross-resistance to Cry11B were much higher and were directly related to the complexity of the B. thuringiensis subsp. israelensis Cry toxin mixtures used to select the resistant mosquito strains. The LC95 RR obtained with the mosquito strains were as follows: 53.1 against Cq4D, which was resistant to Cry11A; 80.7 against Cq4AB, which was resistant to Cry4A plus Cry4B; and 347 against Cq4ABD, which was resistant to Cry4A plus Cry4B plus Cry11A. Combining Cyt1A with Cry11B at a 1:3 ratio had little effect on suppressing Cry11A resistance in Cq4D but resulted in synergism factors of 4.8 and 11.2 against strains Cq4AB and Cq4ABD, respectively; this procedure eliminated cross-resistance in the former mosquito strain and reduced it markedly in the latter strain. The high levels of activity of B. thuringiensis subsp. jegathesan and B. thuringiensis subsp. israelensis, both of which contain a complex mixture of Cry and Cyt proteins, against Cry4- and Cry11-resistant mosquitoes suggest that novel bacterial strains with multiple Cry and Cyt proteins may be useful in managing resistance to bacterial insecticides in mosquito populations.     

Tensile strength of silicon carbide fibre bundles at elevated temperatures

The mechanical properties of commercially available SiC-based ceramic fibres were measured in the temperature range from 400–1300°C. The measurements were performed in air and in inert gas atmospheres, respectively. The Nicalon and Tyranno fibres were tested as filament bundles and the decrease in strength occurring at temperatures above 600 °C was found in both atmospheres. To obtain a well-defined gauge length at the testing temperature, a furnace with very steep temperature gradients at both ends was built. To eliminate grip-induced damage in the heating zone the fibre bundles were fixed outside the furnace with cold grip units. These grips guaranteed the uniformity of load distribution imposed on to each of the individual filaments in the fibre bundle. A significant shrinkage of the fibres occurring during the creep test performed under low loads indicates a change in the microstructure of the fibres at high temperatures.     

Capability and limitation of max- and sum-type construction of Lyapunov functions for networks of iISS systems

This paper addresses the problem of verifying stability of networks whose subsystems admit dissipation inequalities of integral input-to-state stability (iISS). We focus on two ways of constructing a Lyapunov function satisfying a dissipation inequality of a given network. Their difference from one another is elucidated from the viewpoint of formulation, relation, fundamental limitation and capability. One is referred to as the max-type construction resulting in a Lipschitz continuous Lyapunov function. The other is the sum-type construction resulting in a continuously differentiable Lyapunov function. This paper presents geometrical conditions under which the Lyapunov construction is possible for a network comprising $n\ge 2$ subsystems. Although the sum-type construction for general $n>2$ has not yet been reduced to a readily computable condition, we obtain a simple condition of iISS small gain in the case of $n=2$. It is demonstrated that the max-type construction fails to offer a Lyapunov function if the network contains subsystems which are not input-to-state stable (ISS).     

Perceived Facial Expressions of Emotion as Motivational Incentives: Evidence From a Differential Implicit Learning Paradigm.

Participants (N = 216) were administered a differential implicit learning task during which they were trained and tested on 3 maximally distinct 2nd-order visuomotor sequences, with sequence color serving as discriminative stimulus. During training, 1 sequence each was followed by an emotional face, a neutral face, and no face, using backward masking. Emotion (joy, surprise, anger), face gender, and exposure duration (12 ms, 209 ms) were varied between participants; implicit motives were assessed with a picture-story exercise. For power-motivated individuals, low-dominance facial expressions enhanced and high-dominance expressions impaired learning. For affiliation-motivated individuals, learning was impaired in the context of hostile faces. These findings did not depend on explicit learning of fixed sequences or on awareness of sequence-face contingencies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)