排序方式: 共有3条查询结果,搜索用时 0 毫秒
1
1.
Namsar Orapim Autthawong Thanapat Boonprachai Ruttapol Yu Aishui Sarakonsri Thapanee 《Journal of Materials Science: Materials in Electronics》2022,33(9):6536-6548
Journal of Materials Science: Materials in Electronics - The new nanocomposites of silicon dioxide/reduced graphene oxide (SiO2/rGO) and silicon dioxide/nitrogen-doped reduced graphene oxide... 相似文献
2.
Letao Yang Brian M. Conley Susana R. Cerqueira Thanapat Pongkulapa Shenqiang Wang Jae K. Lee Ki-Bum Lee 《Advanced materials (Deerfield Beach, Fla.)》2020,32(43):2002578
Central nervous system (CNS) injuries are often debilitating, and most currently have no cure. This is due to the formation of a neuroinhibitory microenvironment at injury sites, which includes neuroinflammatory signaling and non-permissive extracellular matrix (ECM) components. To address this challenge, a viscous interfacial self-assembly approach, to generate a bioinspired hybrid 3D porous nanoscaffold platform for delivering anti-inflammatory molecules and establish a favorable 3D-ECM environment for the effective suppression of the neuroinhibitory microenvironment, is developed. By tailoring the structural and biochemical properties of the 3D porous nanoscaffold, enhanced axonal growth from the dual-targeting therapeutic strategy in a human induced pluripotent stem cell (hiPSC)-based in vitro model of neuroinflammation is demonstrated. Moreover, nanoscaffold-based approaches promote significant axonal growth and functional recovery in vivo in a spinal cord injury model through a unique mechanism of anti-inflammation-based fibrotic scar reduction. Given the critical role of neuroinflammation and ECM microenvironments in neuroinhibitory signaling, the developed nanobiomaterial-based therapeutic intervention may pave a new road for treating CNS injuries. 相似文献
3.
Chavakorn Samthong Nappaphan Kunanusont Chutimar Deetuam Tanchanok Wongkhan Thanapat Supannasud Anongnat Somwangthanaroj 《Polymer International》2019,68(12):2004-2016
We report here the morphology, thermal and tensile properties of poly(lactic acid) (PLA) blends composed of acrylonitrile butadiene rubber (NBR) with different acrylonitrile contents with/without dynamic vulcanization by dicumyl peroxide (DCP). The interfacial tension of PLA and NBR measured by contact angle measurement decreased as the acrylonitrile content of NBR decreased. Likewise, SEM images showed that the rubber particle size reduced with decreasing acrylonitrile content owing to the stronger interfacial adhesion between the PLA matrix and NBR domains. Incorporation of DCP at 1.0 phr for dynamic vulcanization led to higher crosslink density and, in turn, optimal tensile strength and tensile toughness as a result of the action of PLA‐NBR copolymer as a reactive compatibilizer. The dynamic vulcanization of the blends containing low acrylonitrile NBR gave the most improved tensile properties because the free radicals from DCP decomposition preferentially attacked the allylic hydrogen atoms or double bonds of the butadiene backbone. Accordingly, more NBR macroradicals were generated and probably more PLA‐NBR copolymers were produced. Moreover, further addition of DCP at 2.0 phr provided a large amount of crosslinked NBR gel, which significantly degraded the tensile properties. From the DSC results, dynamic vulcanization lowered the cold crystallization temperature, implying an improvement of cold crystallization. Finally, TGA results showed a higher degradation temperature as a function of DCP content, which suggested that thermal stability increased due to stronger interfacial adhesion as well as higher gel content. © 2019 Society of Chemical Industry 相似文献
1