ρ-混合噪声中ρ-混合信号Min-Max检测的注记

本文考察了ρ-混合噪声中ρ-混合随机信号的 Min-Max 检测问题.首先,将[5]中(?)-混合条件减弱为ρ-混合相依条件;其次,去掉了[5]中式(5)(?)r_n<∞的限制条件;第三,将[5]中常值的弱信号拓广到具有ρ-混合相依的随机信号,故本文改进了[5]中结果.     

基于液压驱动的数控机床上下料 机械手的设计与研究

针对数控机床自动化生产线的工件上下料,设计了机械手的手腕部位和执行手爪的齿轮式机械结构。采用液压控制系统控制机械手的3个执行机构运动,其中,垂直手臂的上升、下降采用垂直升降液压缸,手腕部位的前伸、后缩采用水平伸缩液压缸,执行手爪的夹紧、张开采用柱塞液压缸。对机械手的力学性能进行分析与计算,证明机械手装置简单可靠,具备抓取、搬运30 kg工件的能力。通过对PLC控制系统的设计,使机械手达到了生产线上工件自动上下料的功能要求。     

Gold immunochromatographic sensor for the rapid detection of twenty-six sulfonamides in foods

A gold immunochromatographic sensor (GICS) was developed for the rapid detection of 26 sulfonamides in honey samples.The sensor was based on a group-specific monoclonal antibody (mAb) that can recognize all 26 sulfonamides.Three haptens (hapten 1 with a thiazole ring,hapten 2 with a benzene ring,and hapten 3 with a straight carbon chain) were used for antigen preparation.With hybridoma technology,a group-specific mAb was screened with a 50％ maximal inhibitory concentration (IC50) against sulfathizole (STZ) and the other 25 analogues ranging from 0.08 to 90.18 ng/mL.Mono-dispersed gold nanoparticles were conjugated with the mAb to develop the lateral immunochromatographic strip.A labeled antibody concentration of 0.1 μg/mL and a coating antigen concentration of 0.2 μg/mL in the test line were chosen for strip preparation.Under optimized conditions,the visual limits of detection (vLOD) for the concentrations of STZ,sulfamethoxazole,sulfamethizole,sulfadiazine,sulfamerazine,sulfadimethoxine,sulfamonomethoxine,sulfameter,sulfamethoxypyridazine,and sulfachloropyridazine were 5,0.25,0.25,10,5,10,25,2.5,5,0.25,and 10 μg/kg,respectively.Scanner analysis in honey samples revealed good performance for detection of the 26 sulfonamides.Commercial honey samples were tested with the sensor and positive results were confirmed with high-performance liquid chromatography.The proposed strip sensor provides a convenient method for the rapid and reliable determination of sulfonamides pollutants in honey samples.     

Gold nanoparticle-based paper sensor for ultrasensitive and multiple detection of 32 (fluoro)quinolones by one monoclonal antibody

For rapid and simultaneous detection of (fluoro)quinolones, a broadly specific monoclonal antibody (mAb) that recognizes 32 (fluoro)quinolone antibiotics was prepared using a mixture of a norfloxacin derivative and a sarfloxacin derivative as the hapten. An immunochromatographic strip based on gold nanoparticles (AuNPs) was then assembled with goat anti-mouse antibody and antigen (sarfloxacin coupled to ovalbumin), used to form the C line and T line, respectively. This antigen competes with the (fluoro)quinolones in a sample incubated with mAbs labeled with AuNPs. The strip can detect 32 (fluoro)quinolones including oxolinic acid, nalidixic acid, miloxacin, pipemidic acid, piromidic acid, rosoxacin, cinoxacin, norfloxacin, pefloxacin, lomfloxacin, enofloxacin, fleroxacin, ciprofloxacin, enrofloxacin, dafloxacin, orbifloxacin, sparfloxacin, gemifloxacin, besifloxacin, balofloxacin, gatifloxacin, moxifloxacin, nadifloxacin, ofloxacin, marbofloxacin, flumequine, pazufloxacin, prulifloxacin, sarafloxacin, difloxacin, trovafloxacin, and tosufloxacin in milk within 10 min with the naked eye. The cut-off values of the strip range from 1 to 100 ng/mL and the limits of detection are 0.1–10 ng/mL. The strip does not cross-react with antibiotics including tetracycline, sulfamethazine, ampicillin, erythromycin, aflatoxin B1, or gentamicin. In short, this immunochromatographic strip is a very useful tool for the primary screening of (fluoro)quinolones in milk.

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轮胎气泡边缘检测算法的研究

针对轮胎激光剪切散斑干涉图像背景中存在大量条纹的特点,为避免其对气泡边缘检测产生妨碍,主要对其边缘检测算法进行了研究.给出了对常用的几种算子进行边缘检测后的轮胎激光剪切散斑干涉图像,并分析了其在处理图像时的不适用性,设计出基于模糊理论的小波多尺度边缘检测算法.在多尺度边缘检测过程中,设计了适合的模糊算子,改善了轮胎气泡边缘检测的效果.由仿真结果可知:本文设计的算法与常用边缘检测算法相比,更好地标记出了轮胎气泡的边缘图像,滤除图像中的伪边缘.     

Chirality‐Based Biosensors

The fabrication of chiral nanostructures gives rise to characteristic chiroptical activity, which can be used for chirality‐based biosensors. Great progress is made in the use of nanoassemblies for the construction of chiral nanoparticle dimers, pyramids, helices, and twisted structures, and their chiroptical activities correlate with diverse structural geometries and enantiomeric configurations. In DNA‐hybridization‐based chiral nanoassemblies, the assembly parameters, such as the components, gaps, multicomponents, and the aftergrowth of metal, can result in multiple bands and enhanced chiroptical effects. Based on known chiral nanostructures, the existing chiral nanoassembly‐based biosensors together with their targets and signal amplification strategies are reviewed. Chirality involves multiple signals, and multitarget biosensors are introduced with newly developed chiral architectures for the accurate and reliable monitoring of biomarkers in living cells. The interactions between chiral nanoarchitectures and biosystems are also highlighted, which are important not only in the chiral dynamic switching of nano‐objects for biomonitoring, but also in manipulating cell growth, proliferation, and adhesion. The future perspectives on chiral fabrication and its use in biosensors are also comprehensively discussed.     

带测量误差的平稳信号相关函数的外推

本文首先给出带测量误差的一维平稳信号相关函数的外推;然后,在适当条件下给出二维平稳信号相关函数的两种外推.