全文获取类型
收费全文 | 974篇 |
免费 | 37篇 |
学科分类
工业技术 | 1011篇 |
出版年
2023年 | 7篇 |
2022年 | 23篇 |
2021年 | 40篇 |
2020年 | 21篇 |
2019年 | 13篇 |
2018年 | 23篇 |
2017年 | 27篇 |
2016年 | 33篇 |
2015年 | 32篇 |
2014年 | 29篇 |
2013年 | 60篇 |
2012年 | 51篇 |
2011年 | 57篇 |
2010年 | 37篇 |
2009年 | 35篇 |
2008年 | 50篇 |
2007年 | 44篇 |
2006年 | 35篇 |
2005年 | 21篇 |
2004年 | 24篇 |
2003年 | 18篇 |
2002年 | 21篇 |
2001年 | 23篇 |
2000年 | 11篇 |
1999年 | 24篇 |
1998年 | 39篇 |
1997年 | 29篇 |
1996年 | 23篇 |
1995年 | 20篇 |
1994年 | 16篇 |
1993年 | 14篇 |
1992年 | 12篇 |
1991年 | 4篇 |
1990年 | 10篇 |
1989年 | 14篇 |
1988年 | 12篇 |
1987年 | 7篇 |
1986年 | 5篇 |
1985年 | 9篇 |
1984年 | 4篇 |
1983年 | 2篇 |
1982年 | 5篇 |
1981年 | 3篇 |
1980年 | 2篇 |
1979年 | 2篇 |
1977年 | 2篇 |
1976年 | 4篇 |
1975年 | 2篇 |
1971年 | 2篇 |
1939年 | 4篇 |
排序方式: 共有1011条查询结果,搜索用时 15 毫秒
1.
2.
International scientific collaboration is very sensitive to political and economic changes in a country or a geopolitical region. Collaboration in research is reflected by the corresponding coauthorship of the published results which can be analysed with the help of bibliometric methods. Based on data from theScience Citation Index (SCI), the change of annual international coauthorship patterns ofBulgaria, Czechoslovakia, Hungary, Poland andRomania have been analysed for the periods 1981–1985 and 1984–1993, respectively. It is shown that international collaboration was not developing similarly in the countries under study. Whilst scientific communities of Hungary and Poland have already been opening in the early 80s, the international collaboration of the other East-European countries was still dominated by COMECON relations till 1989. As expected, since 1990 an increasing scientific collaboration with highly developed countries can be observed in all five countries. At the same time, scientific collaboration with the former communist countries shows a clear decline. The great share of international co-authorship links is some countries reflect various tendencies part of which are interpreted with the help of a cardiologic model. 相似文献
3.
Birgit Kanngießer Andreas-Germanos Karydas Dimosthenis Sokaras Stefan Röhrs Joseph Salomon 《Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms》2007,264(2):383-388
The paper describes a novel experiment characterized by the development of a confocal geometry in an external Micro-PIXE set-up. The position of X-ray optics in front of the X-ray detector and its proper alignment with respect to the proton micro-beam focus provided the possibility of carrying out 3D Micro-PIXE analysis. As a first application, depth intensity profiles of the major elements that compose the patina layer of a quaternary bronze alloy were measured. A simulation approach of the 3D Micro-PIXE data deduced elemental concentration profiles in rather good agreement with corresponding results obtained by electron probe micro-analysis from a cross-sectioned patina sample. With its non-destructive and depth-resolving properties, as well as its feasibility in atmospheric pressure, 3D Micro-PIXE seems especially suited for investigations in the field of cultural heritage. 相似文献
4.
5.
Nadine Kretschmer Antje Hufner Christin Durchschein Katrin Popodi Beate Rinner Birgit Lohberger Rudolf Bauer 《International journal of molecular sciences》2021,22(5)
Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment is challenging, and survival rates are very low. In previous studies, we showed that the constituents of the roots of Onosma paniculata as well as a synthetic derivative of the most active constituent showed promising results in metastatic melanoma cell lines. In the current study, we address the question whether we can generate further derivatives with optimized activity by synthesis. Therefore, we prepared 31, mainly novel shikonin derivatives and screened them in different melanoma cell lines (WM9, WM164, and MUG-Mel2 cells) using the XTT viability assay. We identified (R)-1-(1,4-dihydro-5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl 2-cyclopropyl-2-oxoacetate as a novel derivative with even higher activity. Furthermore, pharmacological investigations including the ApoToxGloTM Triplex assay, LDH assay, and cell cycle measurements revealed that this compound induced apoptosis and reduced cells in the G1 phase accompanied by an increase of cells in the G2/M phase. Moreover, it showed hardly any effects on the cell membrane integrity. However, it also exhibited cytotoxicity against non-tumorigenic cells. Nevertheless, in summary, we could show that shikonin derivatives might be promising drug leads in the treatment of melanoma. 相似文献
6.
Universal Access in the Information Society - Access to trustworthy information is a premise for participation in a democratic society. However, locating useful and valid information may not be a... 相似文献
7.
Janine Glänzel Arnd Meyer Roman Unger Michael Bräunig Volker Wittstock Steffen Ihlenfeldt 《The International Journal of Advanced Manufacturing Technology》2017,88(5-8):1279-1288
A new interdisciplinary approach is discribed to identifying unknown parameters using an extended version of the known interval bisection method. This developed method is based on the use of finite elements for calibrating the simulation calculation. The resulting thermo-elastic deformations which occur in drilling processes with impaired cooling lubrication are to be used as correction values for tool positioning in the NC control. Based on the strong impact on workpiece temperature of machining, a simulation approach is presented for calculating the temperature fields and their thermo-elastic consequences. In addition, methods are presented to correct these effects. This paper particularly deals with the temperature fields of drilling operations. Special attention is paid to the technique employed for iterative numerical determination of the unknown heat flux η w and heat transfer coefficient \(\bar {\gamma }\) values. Finally, the data obtained from experiments are compared with those achieved by numerical simulation in order to verify the efficiency of simulation and determination of parameters. 相似文献
8.
Felix Schmutzler Christopher Zschiesche Juliane Titus David Poppitz Jens Freiding Rainer Rakoczy Andreas Reitzmann Roger Gläser 《化学,工程师,技术》2021,93(6):981-989
The hydroisomerization of two long-chain n-alkane mixtures was investigated over bifunctional Pt/H-ZSM-5 catalysts before and after dealumination of preshaped zeolite/binder pellets. The hydroisomerization over the dealuminated catalysts leads to more isomers and less cracking products. Consequently, higher ratios of multi- to mono-branched isomerization products are formed as expected for large- rather than medium-pore zeolites. This indicates a higher availability of space in the vicinity of the active sites and provides an attractive route to make medium-pore zeolites suitable for upgrading higher boiling hydrocarbon feeds. 相似文献
9.
Guido Böttcher Dennis Allerkamp Daniel Glöckner Franz-Erich Wolter 《The Visual computer》2008,24(10):911-922
Real-time cloth simulation involves many computational challenges to be solved, particularly in the context of haptic applications,
where high frame rates are necessary for obtaining a satisfying experience. In this paper, we present an interactive cloth
simulation system that offers a compromise between a realistic physics-based simulation of fabrics and a haptic application
meeting high requirements in terms of computation speed. Our system allows the user to interact with the fabric using two
fingers. The required performance of the system is achieved by introducing an intermediate layer responsible for the simulation
of the small part of the surface being in contact with the fingers. Additionally we separate the possible contact situations
into different cases, each being individually handled by a specialised contact algorithm.
相似文献
Franz-Erich WolterEmail: |
10.
Hoyer D Friedrich H Frank B Pompe B Baranowski R Zebrowski JJ Schmidt H 《Computer methods and programs in biomedicine》2006,81(3):246-255
Heart rate variability (HRV) represents the cardiovascular control mediated by the autonomic nervous system and other mechanisms. In the established task force HRV monitoring different cardiovascular control mechanisms can approximately be identified at typical frequencies of heart rate oscillations by power spectral analysis. HRV measures assessing complex and fractal behavior partly improved clinical risk stratification. However, their relationship to (patho-)physiology is not sufficiently explored. Objective of the present work is the introduction of complexity measures of different physiologically relevant time scales. This is achieved by a new concept of the autonomic information flow (AIF) analysis which was designed according to task force HRV. First applications show that different time scales of AIF improve the risk stratification of patients with multiple organ dysfunction syndrome and cardiac arrest patients in comparison to standard HRV. Each group's significant time scales correspond to their respective pathomechanisms. 相似文献