One-year prevalence of psychiatric disorder in Ontarians 15 to 64 years of age

OBJECTIVE: To present the one-year prevalence of 14 psychiatric disorders in a community sample of Ontarians aged 15 to 64 years. METHOD: Data on psychiatric disorders were collected on 9953 respondents using the University of Michigan revision of the Composite International Diagnostic Interview (UM-CIDI). DSM-III-R criteria were used to define the psychiatric disorders. RESULTS: Almost 1 in 5 Ontarians (18.6%) had one or more of the disorders measured in the survey. Among 15-to 24-year-olds, 1 in 4 was affected. The distribution of individual disorders varied by sex and age. CONCLUSION: Because of the immense burden of suffering associated with psychiatric disorders, clinical and research efforts in this area should receive high priority within the health budget.     

Towards the comparative exploration of public housing segregation in England and the United States

This paper is an exploration of the treatment of racial minorities by public sector housing agencies in Britain and the United States over the last several decades, with the objective of describing empirical and policy differences and similarities. Public housing programmes in each country have been, at differing points in time, important cornerstone's of the welfare state but each has become a residualised sector of the housing delivery system. In the context of such residualisation, the key issue to consider is whether British council housing is likely to reproduce the patterns of racial segregation, impoverishment, and discrimination which are endemic in the American public housing system.

A variety of administrative agency reports and data, court cases, as well as case studies of race and public housing policies in the US and England have been used in this paper (Smith and Whalley, 1975; Commission for Racial Equality seriatim; Hirsch, 1983; Bauman, 1987; Department of the Environment; Smith, 1989). Unpublished tables for the English Housing Trailer for the 1988 Labour Force Survey were provided by the Department of the Environment.

Despite the presence of such information, there are a number of resource and data gathering concerns that affect the understanding of the interrelationships between race, class, and public housing policy on a comparative basis including: constrained research resources; unreliable data collection procedures; unavailability of time series data; and chronically limited research on civil rights/organisational effectiveness (Liebert, 1981). Despite these shortcomings, there are a significant number of both academic and applied studies in the area which suggest basic themes, issues and hypotheses for future examination.     

A Study of Starch Granule Size and Distribution in 29 Barley Varieties

The starch granule size and distribution has been determined on 29 different samples of barley. There is a wide range in the ratio of small to large granules which varies from a minimum of 5.5:1 to a maximum of 37:1. Small granules were separated from large granules in four varieties and the average weight of the granules determined. From these values the actual percentage of small granules in the original barley starch was determined. Small granule starch may account for from 6.2–30.6% of total starch weight in the varieties examined.     

Mental health supplement to the Ontario Health Survey: methodology

OBJECTIVE: To describe the methodology of a province-wide, cross-sectional, epidemiologic study of psychiatric disorder among those aged 15 years and over living in household dwellings in Ontario. METHOD: Respondents for the survey were drawn from households (N = 13002) participating in a province-wide health survey. One person per household was selected, and 9953 (76.5%) participated. RESULTS: Participants and nonparticipants were similar to each other. An extensive array of data, including measures of psychiatric disorder classified using a revised version of the Composite International Diagnostic Interview (CIDI), are available for all respondents. CONCLUSIONS: The Ontario Health Supplement is contained in a public-use data file at the Ontario Ministry of Health and is available to investigators for study. A strong survey design, careful measurement, and acceptable levels of response provide the rationale for our inviting researchers to access and use the Ontario Health Supplement data base.     

Curing cycle modification for RTM6 to reduce hydrostatic residual tensile stress in 3D woven composites

Triaxial residual tensile stresses resulting after cooling a 3D woven composite from the curing temperature cause cracking in the resin pockets for weave architectures that have high through‐the‐thickness constraint. We show how curing cycle modifications can reduce the hydrostatic tensile stress generated by thermal mismatch during cooling of Hexcel RTM6 epoxy resin constrained in a quartz tube which simulates extreme constraint in a composite. The modified curing schedule consists of a high temperature cure to just before the glass transition, a lower temperature hold that takes the resin through the glass transition thereby freezing in the zero stress state, followed by high temperature cure to bring the resin to full conversion. We show that this process is sensitive to heating rates and can reduce the zero stress state of non‐toughened RTM6 resin to a temperature similar to a commercial rubber‐toughened resin, Cycom PR520. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133, 43373.     

High-throughput method for the production and analysis of large natural product libraries for drug discovery

High-throughput methods were applied to the production, analysis, and characterization of libraries of natural products in order to accelerate the drug discovery process for high-throughput screening in the pharmaceutical and biotechnology industries. Library production integrates automated flash chromatography, solid-phase extraction, filtration, and high-throughput parallel four-channel preparative high-performance liquid chromatography to obtain the libraries in 96- or 384-well plates. Libraries consist of purified fractions with approximately one to five compounds per well. Libraries are analyzed prior to biological screening by a high-throughput parallel eight-channel liquid chromatography-evaporative light scattering detection-mass spectrometry system to determine the molecular weight, number, and quantity of compounds in a fraction. After biological screening, active fractions are rapidly purified at the microgram level and individual compounds are rescreened for confirmation of activity. Structures of active compounds are elucidated by NMR spectroscopy and mass spectrometry. Utilization of a novel microcoil probe allows NMR data to be gathered on 50 microg. As a demonstration, a library was made from the stem bark of Taxus brevifolia. Biological screening in the National Cancer Institute's in vitro panel of three cancer cell lines demonstrates that the process enables the discovery of active anticancer compounds not detected in the flash fractions from which the library originates.     

Investigation of polyaniline processibility using GPC/UV–vis analysis

In this work, we characterized the molecular weight and UV–vis spectra of polyaniline (PANI) simultaneously using a gel permeation chromatography (GPC) system equipped with a photodiode array (PDA) detector. Therefore, we constructed correlations between weight average molecular weight (M_w) values and UV–vis spectral features such as the ratio of quinoid units/benzenoid units (Q/B ratio), and the B peak positions for the continuum of discrete chromatographic fractions of PANI emeraldine base (EB). The correlation is further verified by electrochemical techniques. Using this correlation, we analyzed newly synthesized PANIs and investigated how the synthesis and post-treatment conditions impact the quality, uniformity, and processibility of the PANIs. The study also reveals that the portions with low molecular weights of PANI are more sensitive to the process conditions than those with high molecular weights.     

Psychiatric disorders and dissatisfaction with social relationships: Does type of relationship matter?

The specificity of the association between 9 Axis I psychiatric disorders and quality of the relationship with spouse, relatives, and friends was evaluated for married participants who completed the Ontario Health Survey Mental Health Supplement (N?=?4,933). When the authors controlled for the quality of other social relationships, not getting along with one's spouse was related to 6 disorders, with the strongest associations found for generalized anxiety disorder, major depression, panic, and alcohol problems; 4 associations remained significant when they controlled for comorbid disorders. Not getting along with relatives and friends was generally unrelated to psychiatric disorders when they controlled for the other social relationships. Results indicate that the association between marital quality and psychiatric disorders is not an artifact of general social dissatisfaction and that this association is significant for several disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

A home-based program for the treatment of acute psychosis

There is evidence that home treatment is an effective alternative to hospital admission for patients with acute psychiatric illnesses. This report describes processes necessary to establish and disseminate home treatment programs as well as the impact and comparative cost of a home treatment program developed in Metropolitan Toronto. Organizational analysis revealed a number of essential structures and interactions necessary to facilitate smooth functioning for home treatment programs involving several agencies. Attitudes towards home treatment were positive, symptoms were reduced, family burden decreased, satisfaction was high and home treatment was preferred to hospital admission. Economic data indicate that home treatment is less costly than hospitalization.