全文获取类型
收费全文 | 8714篇 |
免费 | 731篇 |
国内免费 | 14篇 |
学科分类
医药卫生 | 9459篇 |
出版年
2024年 | 21篇 |
2023年 | 214篇 |
2022年 | 137篇 |
2021年 | 328篇 |
2020年 | 230篇 |
2019年 | 296篇 |
2018年 | 643篇 |
2017年 | 487篇 |
2016年 | 603篇 |
2015年 | 443篇 |
2014年 | 708篇 |
2013年 | 887篇 |
2012年 | 824篇 |
2011年 | 830篇 |
2010年 | 620篇 |
2009年 | 317篇 |
2008年 | 299篇 |
2007年 | 242篇 |
2006年 | 250篇 |
2005年 | 189篇 |
2004年 | 109篇 |
2003年 | 132篇 |
2002年 | 134篇 |
2001年 | 115篇 |
2000年 | 102篇 |
1999年 | 87篇 |
1998年 | 30篇 |
1997年 | 16篇 |
1996年 | 7篇 |
1995年 | 4篇 |
1994年 | 6篇 |
1993年 | 7篇 |
1992年 | 17篇 |
1991年 | 17篇 |
1990年 | 18篇 |
1989年 | 11篇 |
1988年 | 8篇 |
1987年 | 15篇 |
1986年 | 12篇 |
1985年 | 7篇 |
1984年 | 3篇 |
1983年 | 4篇 |
1977年 | 3篇 |
1975年 | 3篇 |
1973年 | 4篇 |
1971年 | 2篇 |
1968年 | 3篇 |
1966年 | 3篇 |
1962年 | 1篇 |
1928年 | 1篇 |
排序方式: 共有9459条查询结果,搜索用时 0 毫秒
1.
Irmak Karaca Suzan Güven Yılmaz Melis Palamar Halil Ateş 《Ocular immunology and inflammation》2020,28(6):947-951
ABSTRACT
Purpose
To investigate the effect of 1% tropicamide on anterior chamber aqueous flare (ACAF) measurements acquired with laser flare meter in patients with pseudoexfoliation. 相似文献2.
3.
4.
5.
6.
Summary A method of dermaplaning for acne scarring using a skin graft knife is described. This surgical technique cannot be considered as a form of dermabrasion. Its advantages are reported. 相似文献
7.
Mahmut Koç Ömer Yoldaş Yusuf Alper Kılıç Erdal Göçmen Tamer Ertan Hayrettin Dizen Mesut Tez 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2007,392(5):581-585
Background and aims The aim of this study is to evaluate the predictive accuracy of different scoring systems on surgery for perforated peptic
ulcer referred to an academic department of general surgery in a tertiary reference center.
Patients and methods Seventy-five consecutive patients (Male/female ratio = 64:11; mean age, 44 years; range, 16–85) with perforated peptic ulcer
disease were investigated. Disease severity scores and mortality predictions were calculated using the collected data during
admission. Discrimination and calibration characteristics of each system, namely, the acute physiology and chronic health
evaluation II and III, the simplified acute physiology score II, and the mortality probability models (MPM) II, were determined
by using the area under receiver operating characteristics curve and the Hosmer–Lemeshow goodness-of-fit test, respectively.
Results Among the 75 patients included, there were eight (10.6%) mortalities. All systems had a reliable power of discrimination and
calibration. Among the systems tested, MPM II was the best performing as far as discrimination and calibration characteristics
were considered. The parameters of MPM II system that were related to systemic perfusion of the patient were significantly
positive in patients who died compared to those who survived.
Conclusions MPM II that predicted mortality at admission is better than the other systems in predicting mortality. Results also indicate
the importance of maintenance of systemic perfusion of the patient at the early phases of peptic ulcer perforation. 相似文献
8.
T. V. Peker C. Pelin H. B. Turgut A. Anıl A. Sevim 《European archives of oto-rhino-laryngology》1998,255(8):391-395
Since it covers the lateral wall of the mastoid air system, the suprameatal triangle is of importance to otologic surgeons
during mastoidectomy. Because of this clinical importance, topographic anatomy of the suprameatal spine and depression was
studied on Anatolian skulls. In all, 363 male and 231 female skulls were studied. The most prevalent type of suprameatal spine
resembled a crest and was found in both sexes on the right (77.6%) and left (80%) sides. The absence of a suprameatal depression
was significantly higher in females (right 9.1%; left 8.7%) than in males (right 1.7%; left 2.5%). Suprameatal depressions
were mostly shallow in female subjects, but were mostly observed in males to be at a medium depth or deep.
Received: 5 January 1998 / Accepted: 19 March 1998 相似文献
9.
M Aránzazu Partearroyo H Ostolaza F M Go?i E Barberá-Guillem 《Biochemical pharmacology》1990,40(6):1323-1328
The effects of a variety of detergents (non-ionic, ionic and bile derivatives) on B16 melanoma cells have been examined. Two main effects can be clearly differentiated: loss of cell viability and cell lysis. Under our conditions, cell-surfactant interaction is highly dependent on the nature of the amphiphile (more specifically, on its critical micellar concentration). Loss of cell viability occurs at surfactant concentrations below the critical micellar concentration, i.e. the incorporation of detergent monomers into the cell membranes is enough to impair their barrier function, so that Trypan Blue is no longer actively secreted outside the cell. On the other hand, cell lysis only occurs at or near the critical micellar concentration of the detergent, i.e. when the bilayer-micelle transition may take place. Comparative studies using B16 cells and phospholipid vesicles indicate that the amount of detergent required to induce cell lysis is the same that produces disruption of the lipid bilayer. Thus, our results suggest that membranes are the primary target for the toxicologic effects of surfactants on cells. Moreover, they provide a rationale for the interpretation of other studies in this field: previous results from different laboratories are shown to fit very well our data. 相似文献
10.
Yusuf Orhan Adil Azezli Mahmut Çarin Ferihan Aral Ergin Sencer Senay Molvalılar 《Journal of clinical immunology》1993,13(5):339-343
To evaluate the association of HLA types with Turkish patients with Graves' disease, HLA typing, clinical findings, and thyroid antibodies were correlated. The HLA types, clinical findings (ophthalmopathy and age at onset), and thyroid stimulating hormone (TSH) receptor (TRAb) and antithyroid microsomal antibodies (MAb) were analyzed. Seventy Turkish patients with Graves' disease and 306 control subjects were assessed. Serological HLA typing was performed in HLA A, B, C, DR, and DQ loci. There was a significantly increased prevalence of HLA B8, B49, DR3, DR4, and DR10 in Graves' disease. The association of Graves' disease with HLA DR3 was found to be less strong than previously described. The HLA DR4 antigen may contribute to the predisposition of Graves' disease in Turkey. The results suggest that HLA B7, B13, DR7, DQw2, and DQw3 may confer a protective effect for Graves' disease in Turkey. Patients carrying HLA B12, B18, and B44 haplotypes had a tendency to develop the disease at a later age. The difference from the other studies may be the result of the selection of the controls; in part, of the variability in serological typing reagents; and, also, of the rather weak HLA associations with the disease.This study was presented in part at the Annual Meeting of the National Endocrinology and Diabetes Association, Bursa, Turkey, May 25–28, 1992. 相似文献