Longitudinal recovery pattern of neurosensory deficit after Le Fort I osteotomy

The purpose of this study was to investigate the incidence and recovery pattern of neurosensory deficit (NSD) following Le Fort I osteotomy, and to identify the possible risk factors that might contribute to the complication. A prospective longitudinal observational study on the incidence of NSD was conducted on patients who received Le Fort I osteotomy. Subjective and objective standardized neurosensory assessments were performed preoperatively as the baseline, and postoperatively at 2 weeks, 6 weeks, 3 months, 6 months, 12 months, and 24 months. Possible risk factors for NSD including patient age and sex, surgeon experience, and Le Fort I osteotomy with or without multi-segmentation were analysed. Sixty-six patients (43 female, 23 male) with 132 sides of Le Fort I osteotomy were recruited. The incidence of NSD at 2 weeks, 6 weeks, 3 months, 6 months, 12 months, and 24 months was 81.8%, 59.8%, 39.4%, 19.7%, 7.6%, and 3.2%, respectively. Subjective severity of NSD improved with time. Older age was found to be a risk factor for NSD in the early postoperative period, but there was no difference in the long-term. Patient sex, surgeon experience, and the need for multi-segmentation were not found to be related to the incidence of NSD after Le Fort I osteotomy.     

Comparison of the Fracture Resistance and Fracture Mode of Contemporary Restorative Materials to Overcome the Offset of Mandibular Implant-Supported,Cement-Retained Crowns

Background: The purpose was to compare the fracture resistance and the mode of failure of different contemporary restorative materials to restore implant supported, cement-retained mandibular molars. Methods: Two 5 × 10 mm titanium dental implants were mounted in resin blocks and prefabricated titanium and zirconia abutments were connected to each implant. Each implant received forty crowns resembling mandibular first molars. The specimens were divided into four groups (n = 10/group) for each abutment according to the type of material; Group A: porcelain fused to metal crowns; Group B: monolithic zirconia crowns; Group C: zirconia coping with ceramic veneer; Group D: all ceramic lithium disilicate crowns. Specimens were cemented to the abutments, mounted into a universal testing machine, and vertical static load was applied at a speed of 1 mm/min. The test stopped at signs of visual/audible fracture/chipping. Fracture resistance values were analyzed using ANOVA and Tukey’s tests (α ≤ 0.05). The modes of failure were visually observed. Results: A statistically significant difference (p < 0.001) of the fracture resistance values among tested groups was found. The group that showed the highest fracture resistance was Group A for both the titanium and the zirconia abutments (3.029 + 0.248 and 2.59 ± 0.39, respectively) while Group D for both abutments (1.134 + 0.289 and 1.68 ± 0.13) exhibited the least resistance. Conclusions: Fracture resistance and fracture mode varied depending on type of restorative material. For both titanium and zirconia abutments, porcelain fused to metal showed the highest fracture resistance values followed by monolithic zirconia.     

The correlation between non-O blood group type and recurrent catheter-associated urinary tract infections in critically ill patients: A retrospective study

ObjectiveTo investigate the correlation between the ABO blood group and the risk of recurrent catheter-associated urinary tract infections (CA-UTI) and multi-drug resistant (MDR) organism reinfection in the critically ill.MethodsThis retrospective cohort study enrolled adult patients admitted to the intensive care unit (ICU) with confirmed CA-UTI to investigate the correlation between ABO type and the susceptibility to recurrent, reinfection and MDR reinfection. Patients were classified into two groups based on ABO type (O blood group versus non-O blood group).ResultsA total of 81 patients were included in the study: 37 in the O blood group and 44 in the non-O blood group. Patients in the O blood group were associated with significantly lower odds of recurrent CA-UTI (adjusted odds ratio 0.28; 95% confidence interval 0.08, 0.95), a shorter ICU length of stay (LOS) (estimate [SE] –0.24 [0.05]), hospital LOS (estimate [SE] –0.15 [0.03]) and mechanical ventilation duration (estimate [SE] –0.41 [0.07]) compared with the non-O blood group type.ConclusionNon-O blood group type might be a risk factor for recurrent CA-UTI and infection with MDR organism.