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1.
Lucy Yardley David Papo Adolfo Bronstein Michael Gresty Mark Gardner Nilli Lavie Linda Luxon 《Neuropsychologia》2002,40(4):373-383
The aim of this series of experiments was to determine whether attention is normally required for continuously processing vestibular information concerning orientation, or is required only when orientation is disrupted (eg by vestibular dysfunction or by conflicting visual and vestibular orientation cues). In the first two studies, healthy subjects were passively oscillated, and indicated when they perceived they were passing through their starting position. There was only weak evidence for interference between performance on this 'continuous orientation monitoring task' and on concurrent mental tasks. However, a third study showed that when patients with vestibular imbalance carried out the continuous orientation monitoring task their performance on a concurrent mental arithmetic task was substantially impaired. This dual task interference was correlated with inaccuracy in judging orientation on the continuous orientation monitoring task, which in turn correlated with severity of recent vestibular symptomatology (assessed by questionnaire). In a fourth experiment, disorientation was induced in healthy subjects by rotating the visual field about the line of sight. Bidirectional interference was observed between monitoring orientation (assessed by accuracy in setting a rod to the perceived vertical) and performance of an arithmetic task. Dual task interference was correlated with baseline levels of disorientation induced by the visual field, as indicated by inaccuracy in judging the visual vertical. These findings suggest that monitoring orientation makes significant demands upon cortical processing resources when disorientation is induced, whether the disorientation results from deficient sensory functioning or from ambiguous perceptual information. 相似文献
2.
An extensive field survey allowed us to expand the geographical distribution of the scorpion Tityus perijanensis in the Perijá range, western Zulia State, Venezuela, including areas where adult cases of severe scorpionism have been reported. 16S ribosomal RNA (rRNA) gene sequencing, DL(50) determination, and native PAGE suggest low genetic and venom proteomic divergence across the distribution range. The results also indicate phylogenetic divergence between T. perijanensis and T. discrepans, the species prevalent in northcentral Venezuela. T. perijanensis venom lethality (0.91-0.94 mg/kg) is comparable to that of the Brazilian T. serrulatus and ranks highest among toxic Venezuelan Tityus studied so far. The data indicate that the Perijá range should be included amongst the endemic areas of scorpionism of Venezuela and Colombia. 相似文献
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4.
Paolo Ammendola Adolfo Zambelli Leone Oliva Teodorico Tancredi 《Macromolecular chemistry and physics.》1986,187(5):1175-1188
The chain propagation rate constants for the polymerization of ethylene and propene in the presence of δ-TiCl3/Al(CH3)3 at 22 °C are determined by means of a 13C NMR analysis of suitable block copolymers. The numerical values of the rate constants are compared with those previously reported. 相似文献
5.
Antonio Z Gimeno‐García Adolfo Parra‐Blanco David Nicols‐Prez Cipriano Manzano‐Sanz Rafael Mndez‐Medina Enrique Quintero 《Digestive endoscopy》2006,18(2):144-146
Gastric mucormycosis involvement is a rare condition that usually occurs in inmunocompromised patients and frequently has a fatal outcome. We report the case of a 73‐year‐old woman admitted to the intensive care unit with severe bleeding after an acute pulmonary disease. Upper endoscopy disclosed wide and deep necrotic ulcers in the body and fundus of the stomach and greenish exudates with the antrum and the duodenum undamaged. Autopsy revealed an invasive mucormycosis and a severe atheromatosis. Several predisposing factors for mucormycosis infection have been reported until now. We postulate that ischemic gastritis could be a predisposing factor for colonization of zygomycete. 相似文献
6.
Colorectal cancer is one of the most common malignancies in developed countries. Although guaiac-based fecal occult blood
tests have proven their efficacy for screening, they have major drawbacks. Immunochemical fecal occult blood tests are theoretically
superior as they can detect very small amounts of hemoglobin, and they are specific to human hemoglobin. Recently many different
immunochemical tests have been marketed, with variations in hemoglobin detection limit, mechanism of action, sample collection
method, and test development. Molecular tests represent an alternative to fecal blood tests, which have been designed to detect
certain fecal DNA mutations, or aberrant gene methylation (either hyper-or hypomethylation). In this review, we discuss a
selection of the most significant studies published in the last 3 years regarding noninvasive tools for colorectal cancer
screening. 相似文献
7.
Rajashree Gudi Adolfo Elizalde Swarna K. Gogineni Michael J. Macera Adolfo Badillo Ram S. Verma 《Cancer Genetics and Cytogenetics》1996,90(2):142-145
A patient was referred with a high leukocyte count and diagnosed with chronic myelogenous leukemia (CML). Although practically asymptomatic since the time of diagnosis, he had a variable and inconsistent response to treatment. All of his bone marrow cells had a complex, three-way translocation, involving chromosomes 4, 9 and 22. Translocation of chromosome 4 to chromosome 9 was undetectable by routine cytogenetic techniques; however, by the fluorescence in situ hybridization technique, a three-way translocation was identified, 46,XYt(4;9;22)(p16;q34;q11). Although, other chromosomes are frequently involved in complex or variant translocations with chromosome 9 and 22, participation of chromosome 4 is a very rare event. So far, two previous cases have been described in the literature with translocations involving chromosome 4p16. We present a third case of CML having similar break points whose clinical presentation is unusual. 相似文献
8.
Eye movements induced by lateral acceleration steps
Effect of visual context and acceleration levels
C. C. Gianna Michael A. Gresty Adolfo M. Bronstein 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1997,114(1):124-129
Eye movement responses were obtained from six normal subjects exposed to randomly ordered rightwards/leftwards linear acceleration
steps of 0.05 g, 0.1 g or 0.24 g amplitude and 650 ms duration along the inter-aural axis. With the instruction to gaze passively into the darkness, compensatory nystagmus was evoked with slow-phase velocity sensitivity of 49° s−1
g
−1. When subjects viewed earth-fixed targets at 30 cm, 60 cm or 280 cm, eye movements at 130 ms from motion onset were proportional to acceleration and inversely proportional
to target distance, before the onset of visually guided eye movements. Our results show that a modulation with viewing distances
of the earliest human otolith-ocular reflexes occurs in the presence of pure linear acceleration. However, full compensation
was not attained for the nearer targets and higher accelerations.
Received: 31 January 1996 / Accepted: 30 September 1996 相似文献
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10.
Xavier Nogués Francisca Sánchez-Martinez Xavier Castells Adolfo Díez-Pérez Rosa Ana Sabaté Irene Petit Ariadna Brasé Juan Pablo Horcajada Roberto Güerri-Fernández Julio Pascual 《Journal of the American Medical Directors Association》2021,22(5):939-942
A Coronavirus Disease 2019 (COVID-19)–specific Hospital-at-Home was implemented in a 400-bed tertiary hospital in Barcelona, Spain. Senior or immune-compromised physicians oversaw patient care. The alternative to inpatient care more than doubled beds available for hospitalization and decreased the risk of transmission among patients and health care professionals. Mild cases from either the emergency department or after hospital discharge were deemed suitable for admission to the Hospital-at-Home. More than half of all patients had pneumonia. Standardized protocols and management criteria were provided. Only 6% of cases required referral for inpatient hospitalization. These results are promising and may provide valuable insight for centers undertaking Hospital-at-Home initiatives or in the case of new COVID-19 outbreaks. 相似文献