Physical design of the VCI wrappers for the on-chip packet-switched network named SPIN

This paper presents the physical design methodology of the VCI/SPIN wrappers. The challenge was the validation of the wrappers’ specification with Alliance CAD Tools.A wrapper is a standard gateway used by a subscriber to access an interconnect. Because there are as many wrappers as subscribers, it is relevant to have an estimation of the wrapper’s area, its frequency and then compare these results to the router’s.The interest to perform this study with academic tools is to show that commercial tools are not the unique way for experimentations.     

MERIS observations of chlorophyll-a dynamics in Erhai Lake between 2003 and 2009

The Medium Resolution Imaging Spectrometer (MERIS) was used to investigate the spatial and temporal dynamics of chlorophyll-a (chl-a) in Erhai Lake, the second largest freshwater lake in the Yunnan province of China. Six chl-a retrieval models, including four Basic ERS & Envisat (A)ATSR and Meris Toolbox (BEAM) software-incorporated algorithms and MERIS three-band and two-band models, were validated to find the best fit to extract chl-a concentration in Erhai Lake. With a chl-a range of 5–15 mg m^–3, the Lakes/Eutrophic method showed the best performance. The algorithm was then applied to eight-year cloud-free MERIS images between 2003 and 2009, with seasonal and inter-annual variability analysed. Long-term chl-a distributions of Erhai Lake revealed significant seasonal and inter-annual variability. The mean chl-a of the south lake was higher in summer (14.3 mg m^–3) than in spring (10.1 mg m^–3), while generally lower chl-a was found in the north lake with a mean chl-a of 6.4 mg m^–3 in spring and 9.0 mg m^–3 in summer, respectively. An increasing trend was found between 2006 and 2009, and the increasing rate was 12.9% for annual chl-a of the entire lake. While chl-a seasonality was attributed to the seasonal changes of the local temperature, the inter-annual variation was possibly linked to the discharged wastewater from Dali City. This work could provide critical information for decision-makers to manage Erhai Lake’s aquatic ecosystems.     

Personalization of cardiac motion and contractility from images using variational data assimilation

Personalization is a key aspect of biophysical models in order to impact clinical practice. In this paper, we propose a personalization method of electromechanical models of the heart from cine-MR images based on the adjoint method. After estimation of electrophysiological parameters, the cardiac motion is estimated based on a proactive electromechanical model. Then cardiac contractilities on two or three regions are estimated by minimizing the discrepancy between measured and simulation motion. Evaluation of the method on three patients with infarcted or dilated myocardium is provided.     

长距离、低成本采购可能会占用流动资金

据工信部日前最新消息：今年上半年，我国西部地区水泥产量为2．3亿吨，同比增长25．9％，增速远高于东部和中部地区。但西部地区水泥出厂价格则呈持续下降态势。     

Comparison of autologous bone marrow transplantation and intensive chemotherapy as postremission therapy in adult acute myeloid leukemia. The Groupe Ouest Est Leucémies Aigu?s Myéloblastiques (GOELAM)

Three intensive consolidation strategies are currently proposed to younger adults with acute myeloid leukemia (AML) in first complete remission (CR): allogeneic or autologous bone marrow transplantation (BMT) and intensive consolidation chemotherapy (ICC). Patients aged 15 to 50 years with de novo AML received an induction treatment with 7 days of cytarabine and either idarubicin or rubidazone. After achievement of a CR, patients up to the age of 40 and having an HLA-identical sibling were assigned to undergo an allogeneic BMT. All the other patients received a first course of ICC with high-dose cytarabine and the same anthracycline as for induction. They were then randomly assigned to either receive a second course of ICC with amsacrine and etoposide or a combination of busulfan and cyclosphosphamide followed by an unpurged autologous BMT. Of 517 eligible patients, 367 had a CR, but only 219 (59.5%) actually received the planned intensive postremission treatment (73 allogeneic BMT, 75 autologous BMT, and 71 ICC). With a median follow-up of 62 months, the 4-year disease-free survival (DFS) of the 367 patients in CR was 39.5%. The 4-year overall survival (OS) of the 517 eligible patients was 40.5%. In multivariate analysis, DFS and OS were influenced only by the initial white blood cell count and by the French-American-British classification. The type of postremission therapy had no significant impact on the outcome. There was no difference in the 4-year DFS and OS between 88 patients for whom an allogeneic BMT was scheduled (respectively, 44% and 53%) and 134 patients of the same age category and without an HLA-identical sibling (respectively, 38% and 53%). Similarly, there was no difference in the outcome between autologous BMT and ICC. The 4-year DFS was 44% for the 86 patients randomly assigned to autologous BMT and 40% for the 78 patients assigned to ICC (P = .41). The 4-year OS was similar in the two groups (50% v 54.5%, P = .72). The median duration of hospitalization and thrombocytopenia were longer after autologous BMT (39 v 32 days, P = .006, and 109.5 v 18.5 days, P = .0001, respectively). After a first course of ICC, a second course of chemotherapy is less myelotoxic than an unpurged autologous BMT but yields comparable DFS and OS rates.     

Relationship between surface energy and adhesion strength in polyethylene—paper composites

This work reports adhesion behaviour of polyethylene on paper, and deals with the surface energy of the materials involved in the manufacture of these composites, and its influence on the adhesion strength, at constant roughness, for the paper substrates. The surface energy of different papers treated with various sizing agents was determined by measuring contact angles according to the Owens-Wendt method. The peeling energy was shown to follow a linear relationship versus the reversible energy of adhesion. This result is explained by the fact that rupture takes place at the interface and that the size of the defect at the interface depends on the spreading coefficient. Corona treatment, applied to strongly sized papers before making the composites, restored the adhesion strength to its original range of values, again demonstrating the thermodynamic character of adhesion in thermoplastic-paper composites.     

1/f noise in the extinction coefficient of an optical fibre

The extinction coefficient, used to express losses in optical fibres due to absorption and diffusion, fluctuates in time with a 1/f spectrum. The authors have measured fluctuations in the intensity of light propagating through optical fibres. Noise measurements as a function of fibre length show that the noise is not due to fluctuations in reflectivity at the ends. The relative noise in the intensity of the transmitted light is proportional to fibre length     

Determination of pre-impact occupant postures and analysis of consequences on injury outcome. Part I: a driving simulator study

This paper considers pre-impact vehicle maneuvers and analyzes the resulting driver motion from their comfort seating position. Part I of this work consists of analyzing the driver behavior during a crash. The study is conducted using the LAMIH driving simulator and involves 76 participants. The emergency situation is created by a truck emerging from behind a tractor on the opposite side of the road and tearing along the participant. The driver positioning throughout the simulation is recorded via five video cameras allowing view of the front scene, the driver face, feet and pedals, hands on the steering wheel and global lateral view. Data related to braking force, seat pressure, muscular activity for major groups of muscles and actions on the steering wheel are also collected.The typical response to this type of emergency event is to brace rearward into the seat and to straighten the arms against the steering wheel, or, to swerve to attempt to avoid the impacting vehicle. While turning the steering wheel, the forearm can be directly positioned on the airbag module at time of crash which represents a potential injurious situation.These positions are used in Part II to determine scenario of positions for numerical simulation of a frontal collision.     

基于混合信号技术的汽车电子单芯片方案

随着汽车部件电子化程度的不断提高，汽车工程师们正积极地寻求车辆系统中的先进控制和接口技术解决方案。目前，汽车系统中用来嵌入这些功能单元的空间和能源十分有限，汽车工程师们正借助于新颖的高压混合信号技术将复杂的——截至目前还不兼容的元件功能集成到一块芯片上。现在，应用与42V车载电压兼容的13T高电压技术已经可以将复杂的数字电路(如