L'experience regionale arabe en matiere d'education aux droits de l'homme dans les situations d'apprentissage informel

This article describes an informal approach to human rights education, which is anchored in reality and based on experience gained throughout the Arab region and more particularly within the Arab Institute for Human Rights. It is argued that the approach of the Institute could be adopted on a larger scale by organisations working in this domain, not only in the Arab region but also in other regions of the world. The article emphasises the essential role of governments and the importance of cooperation between the governmental and non-governmental levels in order to implement this type of human rights education in informal learning situations, and thus to disseminate a universal culture of human rights.     

Microfluidic chip for fast bioassays��evaluation of binding parameters

A seven channel polystyrene (PS) microchip has been constructed using a micromilling machine and a high-temperature assembling. Protein A (PA) has been immobilized by a passive sorption on the microchannel walls. Two bioaffinity assays with human immunoglobulin G (hIgG) as a ligand have been carried out. (i) PA as the receptor and fluorescently labeled hIgG (FITC-hIgG) as the ligand, (ii) PA as the receptor with hIgG as the quantified ligand and fluorescently labeled goat anti-human IgG (FITC-gIgG) as the secondary ligand. One incubation step of the assays took only 5 min instead of hours typical for enzyme-linked immunosorbent assay applications. Calibration curves of the dependence of a fluorescence signal on the hIgG concentration in a sample have been obtained in one step due to a parallel arrangement of microchannels. A mathematical model of the PA-FITC-hIgG complex formation in the chip has been developed. The values of the kinetic constant of the PA-FITC-hIgG binding (k_on=5.5 m³ mol⁻¹ s⁻¹) and the equilibrium dissociation constant of the formed complex (K_d≤3×10⁻⁶ mol m⁻³) have been obtained by fitting to experimental data. The proposed microchip enables fast evaluation of kinetic and equilibrium constants of ligand-receptor bioaffinity pairs and the ligand quantification. As the use of microfluidic chips for immunoassays is often limited by price, we used procedures and chemicals that allow for an inexpensive construction and operation of the microdevice, e.g., temperature assembling as a fabrication technique, detection via an ordinary digital camera, nonspecific polystyrene as a substrate, passive sorption of biomolecules as an immobilization technique, etc.     

Contents Volume 7 2001

Volume Contents

Contents Volume 7 2001     

A tale of Wootz steel

The extraordinary romance and thrilling adventure associated with the tale of wootz steel shows how Indian metallurgists were the world leaders in antiquity in the manufacture of this legendary high-grade steel. In many ways this material was brought to global attention by the writings of Cyril Stanley Smith. Modern metallurgy and materials science rest on the foundation built by the study of this steel during the past three centuries.     

正确认识改革实践过程对人们思想的影响

伴随着改革的深化和社会主义市场经济体制的建立和逐步完善 ,我国社会从经济基础到上层建筑 ,都处在一个重大的变革时期。这场社会变革无论是深度还是广度都是前所未有的。因此 ,这场变革必然会引起人们精神世界的深刻变化。深入地研究和认识这些变化 ,对于分清主流和支流、正确与谬误 ,切实加强和改进思想政治工作不无意义。     

The Long Decay Model of One-Dimensional Projectile Motion

This article introduces a research study on student model formation and development in introductory mechanics. As a point of entry, I present a detailed analysis of the Long Decay Model of one-dimensional projectile motion. This model has been articulated by Galileo (in De Motu) and by contemporary students. Implications for instruction are discussed.

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Associations of Parenting Styles and Dimensions with Academic Achievement in Children and Adolescents: A Meta-analysis

Parents and researchers alike are interested in how to promote children’s academic competence. The present meta-analysis integrates the results of 308 empirical studies on associations of general parenting dimensions and styles with academic achievement of children and adolescents assessed via grade point average or academic achievement tests. Parental responsiveness (warmth), behavioral control, autonomy granting, and an authoritative parenting style were associated with better academic performance both concurrently and in longitudinal studies, although these associations were small in a statistical sense. Parental harsh control, and psychological control, as well as neglectful, authoritarian, and permissive parenting styles were related to lower achievement with small to very small effect sizes. With three exceptions, parenting dimensions and styles also predicted change in academic achievement over time. Moderating effects of child age, ethnicity, reporter on parenting and academic achievement, quality of the parenting and achievement measure, and publication status were identified. It is concluded that associations of academic achievement with general parenting dimensions/styles tend to be smaller than associations of school-specific parental involvement which have been addressed in previous meta-analyses.