同位素稀释-液相/气相-电感耦合等离子体质谱联用等方法为鱼肉中甲基汞成分标准物质准确定值

The fish tissue certified reference material is designed and prepared mainly for evaluating the determining accuracy of methyl mercury in sea fish or other seafood, as well as for a quality control standard. The property value was certified by three different methods, including high performance liquid chromatographic -cold vapor atomic fluorescence spectrometry（HPLC-CVAFS）method and species specific isotope dilution mass spectrometric analysis (IDMS) using an inductively coupled plasma mass spectrometer as detector after liquid chromatography (LC-ICP-MS) or gas chromatography (GC-ICP-MS). The experiment included spiking, extraction, derivatization, separation and detection procedures. The ERM 464 tuna fish reference material was used as the analytical quality control standard. The results obtained from three different methods were in good agreement. And the statistic average values were used as certified values of methylmercury in the fish tissue CRM.     

鱼肉中甲基汞成分标准物质的国际合作研究

甲基汞对人的中枢神经系统有很强的伤害性.海产鱼类是人类饮食中主要的甲基汞来源,对其检测需要用到标准物质进行质量控制和量值溯源.中国计量科学研究院制备了一种新的鱼肉标准物质,并与南开大学化学系、日本国家计量研究院共同合作研究,使用同位素稀释-液相-电感耦合等离子体质谱联用方法(ID-LC-ICPMS)、同位素稀释-气相-电感耦合等离子体质谱联用方法(ID-GC-ICPMS)和高效液相色谱-冷蒸气原子荧光光谱法(HPLC-CVAFS)等多种方法对其中甲基汞成分进行定值.