Pd/Cu-Free Cobalt-Catalyzed Suzuki and Heck Using Green Bio-Magnetic Hybrid and DFT-Based Theoretical Study

Catalysis Letters - Several highly efficient and magnetically recyclable cobalt catalytic systems were prepared using magnetic chitosan and some safe and available organic compounds...     

A Novel Artificially Humanized Anti-Cripto-1 Antibody Suppressing Cancer Cell Growth

Cripto-1 is a member of the EGF-CFC/FRL1/Cryptic family and is involved in embryonic development and carcinogenesis. We designed a novel anti-Cripto-1 artificial antibody and assessed the recognition to the antigen and the potential to suppress the growth of cancer stem cells. First, single chain antibody clones were isolated by bio-panning with the affinity to recombinant Cripto-1 protein from our original phage-display library. Then, the variable regions of heavy chain VH and light chain VL in each clone were fused to constant regions of heavy chain CH and light chain CL regions respectively. These fused genes were expressed in ExpiCHO-S cells to produce artificial humanized antibodies against Cripto-1. After evaluation of the expression levels, one clone was selected and the anti-Cripto-1 antibody was produced and purified. The purified antibody showed affinity to recombinant Cripto-1 at 1.1 pmol and immunoreactivity to cancer tissues and cell lines. The antibody was available to detect the immunoreactivity in tissue microarrays of malignant tumors as well as in Cripto-1 overexpressing cells. Simultaneously, the antibody exhibited the potential to suppress the growth of human colon cancer derived GEO cells overexpressing Cripto-1 with IC₅₀ at approximately 110 nM. The artificially humanized antibody is proposed to be a good candidate to target cancer cells overexpressing Cripto-1.     

Using plasmonic cloaking method on infinite cylindrical structures and its applications

Journal of Computational Electronics - In recent years, cloaking using materials with negative electric permittivity or magnetic permeability has been studied and researched. It has been...     

Finite-time coordination in multiagent systems using sliding mode control approach

Finite-time stability in dynamical systems theory involves systems whose trajectories converge to an equilibrium state in finite time. In this paper, we use the notion of finite-time stability to apply it to the problem of coordinated motion in multiagent systems. Specifically, we consider a group of agents described by fully actuated Euler–Lagrange dynamics along with a leader agent with an objective to reach and maintain a desired formation characterized by steady-state distances between the neighboring agents in finite time. We use graph theoretic notions to characterize communication topology in the network determined by the information flow directions and captured by the graph Laplacian matrix. Furthermore, using sliding mode control approach, we design decentralized control inputs for individual agents that use only data from the neighboring agents which directly communicate their state information to the current agent in order to drive the current agent to the desired steady state. Sliding mode control is known to drive the system states to the sliding surface in finite time. The key feature of our approach is in the design of non-smooth sliding surfaces such that, while on the sliding surface, the error states converge to the origin in finite time, thus ensuring finite-time coordination among the agents in the network. In addition, we discuss the case of switching communication topologies in multiagent systems. Finally, we show the efficacy of our theoretical results using an example of a multiagent system involving planar double integrator agents.     

Accelerated iterative methods for finding solutions of nonlinear equations and their dynamical behavior

In this paper, we present a family of optimal, in the sense of Kung–Traub’s conjecture, iterative methods for solving nonlinear equations with eighth-order convergence. Our methods are based on Chun’s fourth-order method. We use the Ostrowski’s efficiency index and several numerical tests in order to compare the new methods with other known eighth-order ones. We also extend this comparison to the dynamical study of the different methods.     

Synthesis and characterization of hydrophilic nanocomposite coating on glass substrate

Hydrophilic coatings based on 3‐glicidoxy propyl trimethoxy silane (GPTMS) and polyethylene glycol (PEG) were prepared with the incorporation of tetramethoxysilane (TMOS) and silica nanoparticle colloidal suspension by a sol–gel process. Characterization of the coatings has been performed by Fourier Transform Infrared (FTIR) and Attenuated Total Reflectance Infrared (ATR‐IR) techniques. Morphological properties were characterized by Scanning Electron Microscopy (SEM). The distribution of Si atoms in the hybrid system was obtained by Si mapping. The particle size in sol solution of the coating was measured by light scattering analyzer. Optical properties were characterized by using UV–vis spectrophotometer. The hydrophilicity of the coating was determined by contact angle measurements, and also the results have been confirmed by surface energy and water uptake investigations. The obtained results indicate that the surfactants affected the contact angles remarkably but did not change the transparency. It has been found that applying silica nano particles leads to coatings with different properties than those using TMOS, while siloxane contents were the same in these two set of coatings. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 5322–5329, 2006     

Implementing a one-bit reversible full adder using quantum-dot cellular automata

Quantum-dot cellular automata (QCA) technique is one of the emerging and promising nanotechnologies. It has considerable advantages versus CMOS technology in various aspects such as extremely low power dissipation, high operating frequency and small size. In this paper, designing of a one-bit full adder is investigated using a QCA implementation of Toffoli and Fredkin gates. Then, a full adder design with reversible QCA1 gates is proposed regarding to overhead and power savings. Our proposed full adder design is more preferable when considering both circuit area and speed. The proposed design uses only two QCA1 gates and maximizes the circuit density and focuses on a layout of the circuit which is minimal in using QCA cells.