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1.
2.
Matsuoka F. Kasai K. Oyamatsu H. Kinugawa M. Maeguchi K. 《Electron Devices, IEEE Transactions on》1994,41(3):420-426
A guideline for n- fully gate overlapped (FOLD) structure design optimization has been studied. From the viewpoint of reliability, the greatest reduction in substrate current directly leads to the most reliable n- design for the FOLD structure. The current path modulation phenomenon due to the trapped charge at the n - extension region dominates the hot-carrier induced characteristics change for conventional lightly doped drain (LDD) structure with side-wall spacer. This phenomenon is minimized in the FOLD structure due to its higher controllability of the gate electrode than the LDD structure at the n- extension region. Furthermore, it was also confirmed that the 0.3 μm optimized FOLD structure can achieve high circuit performance at 3.3 V operation, maintaining hot-carrier resistance 相似文献
3.
Remi Kasai Hideaki Yaegashi Hiroshi Yokoyama Masahiko Yamanaka Hideo Sawada 《Journal of Materials Science》2007,42(24):10228-10238
Fluoroalkanoyl peroxides reacted with FULLERENES [fullerene (C60) and commercially available fullerenes (Nanom MixTR and Nanom BlackTR)] and radical polymerizable comonomers such as acrylic acid, N,N-dimethylacrylamide, N-(1,1-dimethyl-3-oxobutyl)acrylamide, and acryloylmorpholine to afford fluoroalkyl end-capped cooligomers having FULLERENES
in the main chain under very mild conditions. Fluoroalkyl end-capped Nanom Mix and Nanom Black cooligomers thus obtained were
found to exhibit a similar solubility to that of the corresponding fluoroalkyl end-capped cooligomers having fullerene in
the main chain. These fluorinated FULLERENES cooligomers were found to form the nanometer size-controlled self-assembled cooligomeric
aggregates in aqueous solutions. These fluoroalkyl end-capped FULLERENES cooligomers were more effective for solubilizing
fullerene, Nanom Mix and Nanom Black into water, compared to those of the corresponding fluoroalkyl end-capped homooligomers
having no FULLERENES in the main chain. Fluoroalkyl end-capped fullerene- and Nanom Mix-acrylic acid cooligomers were found
to exhibit fluorescence spectra related to fullerene and Nanom Mix in cooligomers, respectively, in aqueous solutions. Additionally,
these fluorinated fullerene- and Nanom Mix-acrylic acid cooligomers were able to increase chemiluminescence intensity related
to luminol, effectively, compared to the corresponding fluorinated acrylic
acid homooligomers. 相似文献
4.
Humidity Sensor Characteristics of Woodceramics 总被引:9,自引:0,他引:9
Kiyokazu Kasai Kiyotaka Shibata Koji Saito Toshihiro Okabe 《Journal of Porous Materials》1997,4(4):277-280
The humidity sensor characteristics of Woodceramics were investigated. The Woodceramics used in this experiment were prepared at 650–900°C. The size of specimens selected was 1 × 1 × 10 mm . One was used as-cut and the other was polished. Above 700°C, the resistance of the specimen was below 50 and the decrease of resistance with increasing relative humidity was small. The specimen prepared at 650°C had a resistance of about 1 k. The resistance of as-cut specimens decreased with increase in relative humidity, but that of the polished specimen did not change significantly. The difference between as-cut and polished samples was explained by the differences in surface micro-structure. 相似文献
5.
Composite films made of silk fibroin (SF) and polyallylamine (PAA) are prepared that contain various compositional ratios. These materials are analyzed to elucidate the resulting physical properties and to assess their potential toward advanced applications as industrial materials. The composite films are obtained from a SF and PAA binary system by dry casting from aqueous solution. These composite films exhibit excellent processability such as film forming capabilities, and the elongation at break is increased in the wet state. The differential scanning calorimetry (DSC) curves of the composites suggest that a mutual interaction takes place between the SF and PAA. This interaction is believed to occur because the endothermic peak, corresponding to the individual polymer, shifts with increasing SF content. The random coil conformation of the SF is present, regardless of the PAA blending, as confirmed by FTIR and DSC measurements. Additionally, living cells from Antheraea pernyi and Bombyx mori insect tissues are shown to grow effectively on the composite films. Maximum growth levels occur when the cultivation flask is coated with the material in SF/PAA ratios of 75:25 to 25:75. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 84: 1963–1970, 2002; DOI 10.1002/app.10491 相似文献
6.
High oleic acid oil suppresses lung tumorigenesis in mice through the modulation of extracellular signal-regulated kinase cascade 总被引:2,自引:0,他引:2
Yamaki T Yano T Satoh H Endo T Matsuyama C Kumagai H Miyahara M Sakurai H Pokorny J Shin SJ Hagiwara K 《Lipids》2002,37(8):783-788
This study was undertaken to estimate the effect of dietary high oleic acid oil (OA) on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
(NNK)-induced lung tumorigenesis in mice. Diet containing 10% oil was fed to mice through experimental periods. On day 30
after NNK injection (100 mg/kg body weight, i.p.), the treatment increased the level of prostaglandin E2 (PGE2) as well as proliferating cell nuclear antigen, a marker of cell proliferation in a high linoleic acid oil (LA)-fed group
but not in an OA-fed group. The NNK treatment also induced the activation of an extracellular signal-regulated kinase (Erk)
cascade (Erk, Mek and Raf-1) in an LA-fed group. On the other hand, OA feeding abolished the NNK-induced activation of the
Erk cascade. In conjugation with these events, OA feeding reduced lung tumor incidence and tumor multiplicity (percentage
of mice with tumors) in mice compared with LA feeding at the 20th experimental week. These results suggest that OA suppresses
lung tumorigenesis and that this suppression is correlated with the inhibition of PGE2 production and inactivation of the Erk cascade. 相似文献
7.
Toshihiro Nagao Yuji Shimada Yoshie Yamauchi-Sato Takaya Yamamoto Masaaki Kasai Kentaro Tsutsumi Akio Sugihara Yoshio Tominaga 《Journal of the American Oil Chemists' Society》2002,79(3):303-308
A commercial product of CLA contains almost equal amounts of cis-9,trans-11 (c9,t11)-CLA and trans-10,cis-12 (t10,c12)-CLA. We attempted to enrich the two isomers by a two-step selective esterification using Candida rugosa lipase that acted on c9,t11-CLA more strongly than on t10,c12-CLA. An FFA mixture containing CLA isomers was esterified with an equimolar amount of lauryl alcohol in a mixture of 20%
water and the lipase. When the esterification of total FA reached 50%, two isomers were fractionated in a good yield: t10,c12-CLA was enriched in FFA, and c9,t11-CLA was recovered in lauryl esters. The FFA were esterified again to enrich t10,c12-CLA. At 27.3% esterification of total FA, the t10,c12-CLA content in FFA increased to 64.8 wt% with 89.3% recovery: The ratio of the content of t10,c12-CLA to that of two isomers was 95.9%. Lauryl esters obtained by the single esterification were employed for enrichment
of c9,t11-CLA. After the esters were hydrolyzed, the resulting FFA were esterified again with lauryl alcohol. At 62.0% esterification
of total FA, the c9,t11-CLA content in lauryl esters increased to 73.3 wt% with 79.4% recovery: The ratio of the content of c9,t11-CLA to that of two isomers was 95.6%. In a 600-g-scale purification, molecular distillation was effective in separating
the reaction mixture into lauryl alcohol, FFA, and lauryl ester fractions. 相似文献
8.
Spinal-Formed Context-Free Tree Grammars 总被引:1,自引:0,他引:1
In this paper we introduce a restricted model of context-free tree grammars called spine grammars, and study their formal
properties including considerably simple normal forms. Recent research on natural languages has suggested that formalisms
for natural languages need to generate a slightly larger class of languages than context-free grammars, and for that reason
tree adjoining grammars have been widely studied relating them to natural languages. It is shown that the class of string
languages generated by spine grammars coincides with that of tree adjoining grammars. We also introduce acceptors called linear
pushdown tree automata, and show that linear pushdown tree automata accept exactly the class of tree languages generated by
spine grammars. Linear pushdown tree automata are obtained from pushdown tree automata with a restriction on duplicability
for the pushdown stacks.
Received May 29, 1998, and in revised form April 27, 1999, and in final form May 10, 1999. 相似文献
9.
Laser-Sintered Barium Titanate 总被引:1,自引:0,他引:1
Toshihiro Kasai Yoshiharu Ozaki Hideki Noda Kenji Kawasaki Kei Tanemoto 《Journal of the American Ceramic Society》1989,72(9):1716-1718
Laser sintering of alkoxy-derived ultrafine BaTiO3 powders was investigated. The temperature increases of the sample with laser irradiation were measured with a thermocouple. It was found that laser irradiation could generate enough heat to sinter ceramics. A slurry was prepared by mixing an alkoxy-derived BaTiO3 powder, binder additives, solvent, and plasticizer. The slurry was tape cast and dried to give a green sheet. The green sheet was laser sintered and was then characterized by SEM, XRD, and density measurements. The effect of burnout before laser irradiation and the characteristic microstructure of laser-sintered BaTiO3 are described. 相似文献
10.
Kazuhiro Nagao Akira Koshino Akane Sugimura-Nagata Aya Nagano Masayuki Komura Akane Ueki Masahide Ebi Naotaka Ogasawara Toyonori Tsuzuki Kenji Kasai Satoru Takahashi Kunio Kasugai Shingo Inaguma 《International journal of molecular sciences》2022,23(6)
p53 immunohistochemistry is considered an accurate surrogate marker reflecting the underlying TP53 mutation status and has utility in tumor diagnostics. In the present study, 269 primary CRCs were immunohistochemically evaluated for p53 expression to assess its utility in diagnostic pathology and prognostication. p53 expression was wild-type in 59 cases (23%), overexpressed in 143 cases (55%), completely lost in 50 cases (19%), and cytoplasmic in 10 cases (4%). p53 immunoreactivity was associated with tumor size (p = 0.0056), mucus production (p = 0.0015), and mismatch repair (MMR) system status (p < 0.0001). Furthermore, among CRCs with wild-type p53 expression, a significantly higher number of cases had decreased CDX2 than those with p53 overexpression (p = 0.012) or complete p53 loss (p = 0.043). In contrast, among CRCs with p53 overexpression, there were significantly fewer ALCAM-positive cases than p53 wild-type cases (p = 0.0045). However, no significant association was detected between p53 immunoreactivity and the “stem-like” immunophenotype defined by CDX2 downregulation and ALCAM-positivity. Multivariate Cox hazards regression analysis identified tubular-forming histology (hazard ratio [HR] = 0.17, p < 0.0001), younger age (HR = 0.52, p = 0.021), and female sex (HR = 0.55, p = 0.046) as potential favorable factors. The analysis also revealed complete p53 loss (HR = 2.16, p = 0.0087), incomplete resection (HR = 2.65, p = 0.0068), and peritoneal metastasis (HR = 5.32, p < 0.0001) as potential independent risk factors for patients with CRC. The sub-cohort survival analyses classified according to chemotherapy after surgery revealed that CRC patients with wild-type p53 expression tended to have better survival than those with overexpression or complete loss after chemotherapy. Thus, immunohistochemistry for p53 could be used for the prognostication and chemotherapy target selection of patients with CRC. 相似文献