Dynamic lithium-ion battery model for system simulation

Presents here a complete dynamic model of a lithium ion battery that is suitable for virtual-prototyping of portable battery-powered systems. The model accounts for nonlinear equilibrium potentials, rate- and temperature-dependencies, thermal effects and response to transient power demand. The model is based on publicly available data such as the manufacturers' data sheets. The Sony US18650 is used as an example. The model output agrees both with manufacturer's data and with experimental results. The model can be easily modified to fit data from different batteries and can be extended for wide dynamic ranges of different temperatures and current rates.     

An actively controlled fuel cell/battery hybrid to meet pulsed power demands

This paper presents the experimental results of an actively controlled fuel cell/battery hybrid power source topology that can be widely used in many applications, such as portable electronic devices, communication equipment, spacecraft power systems, and electric vehicles, in which the power demand is impulsive rather than constant. A step-down DC/DC power converter is incorporated to actively control the power flow between the fuel cell and the battery to achieve both high power and high energy densities. The results show that the hybrid power source can achieve much greater specific power and power density than the fuel cell alone. This paper first demonstrates that an actively controlled hybrid with a 35 W hydrogen-fueled polymer electrolyte membrane fuel cell and a lithium-ion battery pack of six cells yielded a peak power of 100 W, about three times as high as the fuel cell alone can supply, while causing a very limited (10%) weight increase to the whole system. After that, another hybrid source using a different battery array (eight cells) was investigated to further validate the control strategy and to show the flexibility and generality of the hybrid source design. The experimental data show that the hybrid source using an eight-cell battery supplied a peak power of 135 W, about four times that of the fuel cell alone. Finally, three power sources including the fuel cell alone and the two hybrids studied were compared in terms of specific power, power density, volume, weight, etc. The design presented here can be scaled to larger or smaller power capacities for a variety of applications.     

A randomized phase-II study of BB-10010 (macrophage inflammatory protein- 1alpha) in patients with advanced breast cancer receiving 5-fluorouracil, adriamycin, and cyclophosphamide chemotherapy

BB-10010 is a variant of the human form of macrophage inflammatory protein-1alpha (MIP-1alpha), which has been shown in mice to block the entry of hematopoietic stem cells into S-phase and to increase their self-renewal capacity during recovery from cytotoxic damage. Its use may constitute a novel approach for protecting the quality of the stem cell population and its capacity to regenerate after periods of cytotoxic treatment. Thirty patients with locally advanced or metastatic breast cancer were entered into the first randomized, parallel group controlled phase II study. This was designed to evaluate the potential myeloprotective effects of a 7-day regimen of BB-10010 administered to patients receiving six cycles of 5-fluorouracil (5-FU), adriamycin, and cyclophosphamide (FAC) chemotherapy. Patients were randomized, 10 receiving 100 microgram/kg BB-10010, 11 receiving 30 microgram/kg BB-10010, and nine control patients receiving no BB-10010. BB-10010 was well-tolerated in all patients with no severe adverse events related to the drug. Episodes of febrile neutropenia complicated only 4% of the treatment cycles and there was no difference in incidence between the treated and nontreated groups. Studies to assess the generation of progenitor cells in long-term bone marrow cultures were performed immediately preceding chemotherapy and at the end of six dosing cycles in 18 patients. Circulating neutrophils, platelets, CD 34(+) cells, and granulocyte/macrophage colony-forming cell (GM-CFC) levels were determined at serial time points in cycles 1, 3, and 6. The results showed similar hemoglobin and platelet kinetics in all three groups. On completion of the six treatment cycles, the average pretreatment neutrophil levels were reduced from 5.3 to 1.7 x 10(9)/L in the control patients and from 4.3 to 1.9 and 4.5 to 2.5 x 10(9)/L in the 30/100 microgram/kg BB-10010 groups, respectively. Relative to their pretreatment values, 50% of the patients receiving BB-10010 completed the treatment with neutrophil values significantly higher than any of the controls (P = .02). Mobilization of GM-CFC was enhanced by BB-10010 with an additional fivefold increase over that generated by chemotherapy alone, giving a maximal 25-fold increase over pretreatment values. Bone marrow progenitor assays before and after this standard regimen of chemotherapy indicated little long-term cumulative impairment to recovery from chemotherapy. Despite the limited cumulative damage to the bone marrow, which may have minimized the protective value of BB-10010 during this regimen of chemotherapy, better recovery of neutrophils in the later treatment cycles with BB-10010 was indicated in a number of patients.     

Streamer model for ionization growth in a photoconductive powerswitch

The ionization process in a high gain photoconductive GaAs power switch is explored computationally, based on a streamer model. The streamer velocity was found to increase with increasing electric field, decreasing temperature, or increasing background ionization density. The electric field dependence of streamer velocity is consistent with experimental observations, lending support for the model's predictions about the temperature and background ionization density dependencies. The large electric field associated with the highly charged streamer tip allows virtual propagation of the ionization column at speeds above 10 ⁸ cm/s, well in excess of the carrier saturated drift velocity     

Variable polarisation compensator using artificial dielectrics formillimetre and submillimetre waves

A variable polarisation compensator has been designed and demonstrated experimentally at 100 GHz. The device uses two silicon plates with interlocking artificial dielectric surfaces to produce a birefringence that varies with the separation distance. The experimental results indicate a maximum differential phase-shift of 74°, and show good agreement with computer simulations     

Methods for detecting errors in numerically controlled machining ofsculptured surfaces

The numerically controlled (NC) machining of sculptured surfaces is an error-prone process often requiring several attempts before an error-free NC program is produced. A technique designed to move the NC proof process into software is described. The system outputs a color-coded graphics display of the machined surface that shows out-of-tolerance areas. To gain efficiency, surface curvature and cutting-tool size are used as inputs to a surface discretization algorithm, which guarantees that a user-defined level of simulation accuracy is achieved. The simulation time grows linearly in both desired accuracy and in the number of tool movements. In typical test cases, NC programs for complex automotive body panels were simulated and verified in CPU times that ranged between 5 and 30 minutes     

Approximate methods for simulation and verification of numerically controlled machining programs

Algorithms for simulation and verification of Numerically Controlled (NC) machining programs are presented. Compared to NC simulation based on conventional solid modeling systems, these models are designed to give approximate results, but with a substantial decrease in computer time. The surfaces of the part are discretized into a Surface Point Set (SPS) with a point spacing dependent on cutting tool size and shape local surface curvature and the desired accuracy of the approximate simulation. The surface-surface intersection calculations of the solid modeling approach are replaced by the intersection of the surface of the tool movement envelope with straight lines emanating from the surface points. The methods are applicable to both 3 and 5 axis machining. Samples test cases are presented, and implementation and efficiency issues are discussed.