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Examination of blood viscosity at low shear rates using a co-axial cylinder viscometer showed a significant difference between the means of values observed in hypertrigliceridemic patients compared with that of control subjects. This result differs from what has been reported by most workers although generally greater shear rates have been used. Calculation of the "r" coefficient and plotting of the regression line for each shear rate showed that there is no linear correlation between blood viscosity and triglyceridaemia, whose variations occur quite independently. It is suggested that the absence of a correlation between the two parameters examined may depend on various factors, of which the most important are those pertaining to the rheological properties of red blood cells and to the structure and chemical and physical characteristics of the triglyceride molecule and of the lipoproteins and chylomicrons which transport them. 相似文献
3.
Benedetta Pasquini Mohammad Goodarzi Serena Orlandini Giangiacomo Beretta Sandra Furlanetto Bieke Dejaegher 《International Journal of Food Science & Technology》2014,49(5):1351-1359
In this article, discrimination models are presented, relating the origin of honey samples to several variables, being the concentrations of different cations and anions in the honey samples measured by ion chromatography, and parameters that measure/reflect the antioxidant activity of the honey samples. The unsupervised method, principal component analysis, and supervised discrimination methods, such as linear and quadratic discriminant analysis, and classification and regression trees (CART), were applied to evaluate the existence of data patterns and the relationship between geographical origin and the measured parameters. The model with the best predictive ability (%CCRTEST = 66.67%), the best overall % specificity (80%) and the best overall % sensitivity (67%) was found to be CART. It was proven that the mineral content and parameters analysed can provide enough information for the geographical characterisation and discrimination of honey. 相似文献
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Killen Joel D.; Fortmann Stephen P.; Murphy Greer M. Jr.; Hayward Chris; Arredondo Christina; Cromp DeAnn; Celio Maria; Abe Laurie; Wang Yun; Schatzberg Alan F. 《Canadian Metallurgical Quarterly》2006,74(2):286
The authors present results of a randomized clinical trial of the efficacy of extended treatment with bupropion SR in producing longer term cigarette smoking cessation. Adult smokers (N = 362) received open-label treatment (11 weeks) that combined relapse prevention training, bupropion SR, and nicotine patch followed by extended treatment (14 weeks) with bupropion SR or matching placebo. Abstinence percentages were relatively high (week 11: 52%; week 25: bupropion, 42%; placebo, 38%; week 52: bupropion, 33%; placebo, 34%), but bupropion SR did not surpass placebo. Gender and baseline craving level were identified as significant, independent moderators of treatment response. Men were more likely to abstain than women (week 11: 59% vs. 43%, p = .001; week 25: 48% vs. 31%, p = .001; week 52: 39% vs. 27%, p = .01). Because most smokers suffer relapse with any current cessation treatment, the comparatively high abstinence percentages achieved in this trial are of interest. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
6.
D Le Roy P Morand S Lengacher M Celio GE Grau MP Glauser D Heumann 《Canadian Metallurgical Quarterly》1996,64(5):1846-1849
PURPOSE: To investigate the clonal origin of malignant cells in recurrent superficial bladder cancer. MATERIALS AND METHODS: We compared the protein expression of p53 and retinoblastoma (Rb) by immunohistochemistry using antibody P1801 and PMG3-245, respectively, in 13 patients at the time of primary superficial bladder cancer resection (6 Ta and 7 T1) and their 15 corresponding recurrences of disease. Mutations in p53 and Rb were inferred on the basis of immunoperoxidase staining. RESULTS: At the time of initial tumor resection, a p53 mutation was observed in 5 patients (39%) and an Rb mutation was observed in 3 (23%). The p53/Rb mutation status of recurrent bladder cancers completely matched their corresponding primary bladder cancer. CONCLUSIONS: The chance that recurrent bladder cancer originated from independent clones in this study was extremely small (p < 10(-6)). This result strongly supports the monoclonal origin of recurrent superficial bladder cancer. 相似文献
7.
Aline Bruna da Silva Celio Wisniewski Jo?o Victor Almeida Esteves Rinaldo Gregorio 《Journal of Materials Science》2010,45(15):4206-4215
Poly(vinylidene fluoride), PVDF, samples containing exclusively the polar β phase were obtained by crystallization from N,N-dimethylformamide (DMF) solution at 60 °C and subsequent pressing. Some of these samples were uniaxially drawn at 120 °C
at draw ratio of 4, resulting in oriented films. Oriented and unoriented samples were characterized as to relative fraction
of β phase, degree of crystallinity and orientation by infrared spectroscopy (FTIR), differential scanning calorimetry (DSC),
and wide-angle X-ray diffraction (WAXD). The dependence on frequency of the real (
e\textr¢ \varepsilon_{\text{r}}^{\prime} ) and imaginary (
e\textr¢¢ \varepsilon_{\text{r}}^{\prime\prime} ) components of the relative permittivity of the samples was determined between 104 and 1.7 × 107 Hz. The coercive field and stable and metastable remanent ferroelectric polarization were determined from the hysteresis
loop obtained by the ramp voltage technique, described in detail in this work. The results allowed verification of the effect
of drawing on structure and of the resulting structure on the dielectric properties, remanent polarization, and coercive field
of β-PVDF. A possible effect of the crystal–amorphous interphase region on the metastable remanent polarization is suggested.
The results obtained with the oriented and unoriented samples were compared with those obtained for films commercialized by
Piezotech S.A. 相似文献
8.
Jarbas J. R. Rohwedder Celio Pasquini Ivo M. Raimundo Jr. M. Concei?ao B. S. M. Montenegro Alberto N. Araújo Cristina M. C. M. Couto 《Journal of Automated Methods and Management in Chemistry》2002,24(4):105-110
A versatile potentiometer that works with electrode arrays in flow injection and/or monosegmented flow systems is described. The potentiometer is controlled by a microcomputer that allows individual, sequential multiplexed or random accesses to eight electrodes while employing only one reference electrode. The instrument was demonstrated by monitoring an array of seven flow-through ion-selective electrodes for Ag(+) and for three electrodes for Cl(-), Ca(2+) and K(+). The figures of merit of the individual and multiplexed (summed) readings of the electrode array were compared. The absolute standard deviation of the measurements made by summing the potential of two or more electrodes was maintained constant, thus improving the precision of the measurements. This result shows that an attempt to combine the signals of the electrodes to produce a more intense signal in the Hadamard strategy is feasible and accompanied by a proportional improvement in the precision of individual measurements. The preliminary tests suggest that the system can allow for 270 determinations per hour, with a linear range from 1.0 x 10(-2) to 1.0 x 10(-4) mol l(-1) for the three di inverted exclamation markerent analytes. Detection limits were estimated as 3.1 x 10(-5), 3.0 x 10(-6) and 1.0 x 10(-5) mol l(-1) for Cl(-), Ca(2+) and K(+), respectively. 相似文献
9.
M. Ponthieu M. Calizzi L. Pasquini J.F. Fernández F. Cuevas 《International Journal of Hydrogen Energy》2014
MgH2, MgH2–TiH2 nanocomposites and their deuterated analogues have been obtained by reactive ball milling and their kinetic and cycling hydrogenation properties have been analysed by isotope measurements and high-pressure differential scanning calorimetry (HP-DSC). Kinetics of material synthesis depends on both Ti-content and the isotopic nature of the gas. For pure Mg, the synthesis is controlled by isotope diffusion in Mg and therefore MgH2 forms faster than MgD2. For the MgH2–TiH2 nanocomposites, the synthesis is controlled by the efficiency of milling. Kinetics of reversible hydrogen/deuterium sorption in nanocomposites have been studied at 548 K. The rate limiting step is isotope diffusion for absorption and Mg/MgH2 interface displacement for desorption. HP-DSC measurements demonstrate that the TiH2 phase acts as a gateway for hydrogen sorption even in presence of MgO and provides abundant nucleation sites for Mg and MgH2 phases. The 0.7MgH2–0.3TiH2 nanocomposite exhibits steady hydrogen storage capacity after 100 cycles of absorption–desorption. 相似文献
10.
JR Passweg G Socié W Hinterberger A Bacigalupo JC Biggs BM Camitta RE Champlin RP Gale E Gluckman EC Gordon-Smith JM Hows JP Klein ML Nugent R Pasquini PA Rowlings B Speck A Tichelli MJ Zhang MM Horowitz MM Bortin 《Canadian Metallurgical Quarterly》1997,90(2):858-864
Bone marrow transplants for severe aplastic anemia were first performed in the 1970s. Transplant regimens, supportive care, and patient selection have changed substantially since then. Our objective was to determine the impact of these changes on transplant outcome. We studied 1,305 recipients of HLA-identical sibling transplants for aplastic anemia between 1976 and 1992, reported to the IBMTR by 179 centers. We compared survival of transplants performed in three intervals (1976 through 1980 [n = 186], 1981 through 1987 [n = 648], and 1988 through 1992 [n = 471]) using Cox proportional hazards regression. Five-year survival (+/-95% confidence interval) increased from 48% +/- 7% in the 1976-1980 cohort to 66% +/- 6% in the 1988-1992 cohort (P < .0001). Risks of graft-versus-host disease (GVHD) and interstitial pneumonia decreased over time, but the risk of graft failure did not. Higher long-term survival resulted primarily from decreased mortality in the first 3 months posttransplantation. Late mortality risks were low and changed little over the intervals studied. In multivariate analysis, changes in transplantation strategies accounted for most but not all of the improved outcome. Use of cyclosporine to prevent GVHD was the most important factor. Changes in patient selection did not seem to explain improved survival. Survival after HLA-identical sibling bone marrow transplantations for aplastic anemia has improved since 1976. Changes in GVHD prophylaxis account for much of this improvement. Other changes may also operate. 相似文献