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91.
Amirah Mohammad-Sidik Jian Sun Ryoung Shin Zhizhong Song Youzheng Ning Elsa Matthus Katie A. Wilkins Julia M. Davies 《International journal of molecular sciences》2021,22(2)
Extracellular ATP (eATP) has long been established in animals as an important signalling molecule but this is less understood in plants. The identification of Arabidopsis thaliana DORN1 (Does Not Respond to Nucleotides) as the first plant eATP receptor has shown that it is fundamental to the elevation of cytosolic free Ca2+ ([Ca2+]cyt) as a possible second messenger. eATP causes other downstream responses such as increase in reactive oxygen species (ROS) and nitric oxide, plus changes in gene expression. The plasma membrane Ca2+ influx channels involved in eATP-induced [Ca2+]cyt increase remain unknown at the genetic level. Arabidopsis thaliana Annexin 1 has been found to mediate ROS-activated Ca2+ influx in root epidermis, consistent with its operating as a transport pathway. In this study, the loss of function Annexin 1 mutant was found to have impaired [Ca2+]cyt elevation in roots in response to eATP or eADP. Additionally, this annexin was implicated in modulating eATP-induced intracellular ROS accumulation in roots as well as expression of eATP-responsive genes. 相似文献
92.
The voltage-gated proton channel, Hv1, also termed VSOP, was discovered in 2006. It has long been suggested that proton transport through voltage-gated proton channels regulate reactive oxygen species (ROS) production in phagocytes by counteracting the charge imbalance caused by the activation of NADPH oxidase. Discovery of Hv1/VSOP not only confirmed this process in phagocytes, but also led to the elucidation of novel functions in phagocytes. The compensation of charge by Hv1/VSOP sustains ROS production and is also crucial for promoting Ca2+ influx at the plasma membrane. In addition, proton extrusion into neutrophil phagosomes by Hv1/VSOP is necessary to maintain neutral phagosomal pH for the effective killing of bacteria. Contrary to the function of Hv1/VSOP as a positive regulator for ROS generation, it has been revealed that Hv1/VSOP also acts to inhibit ROS production in neutrophils. Hv1/VSOP inhibits hypochlorous acid production by regulating degranulation, leading to reduced inflammation upon fungal infection, and suppresses the activation of extracellular signal-regulated kinase (ERK) signaling by inhibiting ROS production. Thus, Hv1/VSOP is a two-way player regulating ROS production. Here, we review the functions of Hv1/VSOP in neutrophils and discuss future perspectives. 相似文献
93.
在多输入多输出环境下,为了能够连续预测出移动用户的信道容量并以此合理地分配用户资源,提出了一种基于动态模式分解(DMD)的信道容量预测方法及其优化方法:基于经验模态分解的选择性归一化动态模式分解(ESN-DMD).仿真结果表明,DMD算法只适用于预测低移速低复杂度的用户信号,ESN-DMD算法可以预测不同移速的用户信道容量. 相似文献
94.
The calculations of total energy, band structure, and electronic density of states and Mulliken population analysis of β-LaNi5 Hx (5≤x≤8) were performed by adopting the method of total energy based on the density functional theory. The augmented plane wave function was selected as the basis set in combination with ultra-soft pseudo-potential technology. The influence of the amount of H absorbed in alloys was discussed in terms of geometry, electronic structure and thermodynamic derived from calculated results. The results show that the amount of H absorbed and the preferred site occupation of the absorbed hydrogen atoms were controlled by the position of Hbands and the energy gap between H-bands and conduction bands. The β-phase hydrides of LaNi5 are most stable when hydrogen atom capacity coating in the range of 6 - 7. 相似文献
95.
水电开发对洄游性鱼类的生境造成了影响,预测目标鱼类洄游期的上溯通道可为修建过鱼设施提供依据,从而减缓其负面效应。本文选取虎渡溪航电工程的下游河段作为研究区域,将长薄鳅、白甲鱼、异鳔鳅鮀作为目标鱼类,针对几种目标鱼类的游泳能力对不同流速进行分区后,得出了适用于多种过鱼目标的流速适宜度曲线,然后对研究区域过鱼期的典型流量进行了数值模拟。根据流速适宜度曲线对研究区域的多种过鱼目标进行了流速适宜度评价,并由评价结果预测了满足多目标过鱼要求的上溯通道。结果表明:流速适宜度评价最优区域出现的位置随流量变化而有所不同,低流量运行条件下出现在主流区域,而高流量运行条件下出现在主流区域两侧;上溯的通道面积占总面积的比例也随流量变化而有所不同,低流量运行条件下的占比约为高流量运行条件下的3 ~ 4倍。根据预测通道特征,对鱼道的进口布置及电站运行调度提供了建议。该结果可为相关鱼类的保护工作提供依据。 相似文献
96.
97.
纯铝等径角挤技术(I)——显微组织演化 总被引:15,自引:4,他引:15
研究了纯铝在 3种 (A、B和C)不同等径角挤工艺中的显微组织演化。结果表明 :纯铝经过等径角挤压变形后 ,其显微组织特征与加工路线有很大的关系。提出了立方元素扭转模型 ,分析了 3种不同加工路线的剪切面和剪切方向 ,较好地解释了采用 3种不同路线挤压后材料显微组织的演化规律。在路线C(各道次挤压间试样旋转 180°)中 ,每次挤压样品总是在相同的剪切面上发生剪切 ,每相邻道次之间的剪切方向相反 ,前一次变形产生的剪切应变被随后紧接着的下一次挤压所抵消 ,这导致了多余的剪切应变 ;在路线A(各道次挤压间试样不旋转 )中 ,有两个相交成 6 0°的剪切面 ,剪切交替地在两个剪切面上进行 ;在路线B(各道次挤压间试样旋转 90°)中 ,存在 4个不同的剪切面和剪切方向 ,挤压交替地在 4个剪切面上进行 ,X ,Y和Z平面上的晶粒都发生了剪切 ,这有利于等轴晶结构的形成 相似文献
98.
LI Yundong ZHANG Tianxiang ZHENG Zhi ZHU Yaoxiao Institute of Metal Research Academia Sinica Shenyang China Professor Institute of Metal Research Academia Sinica Shenyang China 《金属学报(英文版)》1990,3(6):393-397
The solid solubilities of 15 common alloying elements added to the Ll_2-type intermetalliccompound Ni_3Si at 900°C have been estimated,and their substitution modes have been de-duced from the direction of solubility lobe of the compound.It is shown that the alloyingbehaviours in Ni_3Si are determined by both size and electronic factors,i.e.,the substitutionmode is governed by electronic configuration and solubility by the both.An interactionparameter is presented to describe quantitatively the influence of electronic configuration onsubstitution mode and the solubility limit can be successfully explained together with atom radius. 相似文献
99.
通用电子手册数据库录入软件的关键技术 总被引:1,自引:0,他引:1
文章主要讨论了关于通用电子手册数据库录入软件的组成和功能,较为详细地讨论了实际开发中几个关键技术的解决方案.实际设计完成了通用电子手册数据库录入软件模块,并应用于实际工作中,运行良好. 相似文献
100.
S.?H.?Yu H.?S.?Ryoo S.?K.?HwangEmail author D.?H.?Shin 《Metals and Materials International》2003,9(2):107-114
Grain boundary character distribution in equal-channel-angular pressed Zr was studied. Using a die design of 90°/20° and an
operation temperature of 350°C. The initial grain size of 20 μm was reduced to about 270 nm with 4 passes via route Bc. The grain growth kinetics of the recrystallized state was obtained by experiment and Monte-Carlo computer simulation, respectively,
which showed good agreement. Based on kinetics and morphological characteristics, it was concluded that the grain coarsening
mechanism was governed by normal grain growth. No sign of abnormal grain growth was detected either in the experiment or in
simulation despite taking into consideration anisotropy in grain boundary energy as well as its mobility. This indicates that
grain boundaries produced by severely deformed Zr are stable against explosive coarsening. The evolution characteristics of
the microstructure in the present ECA pressed and recrystallized Zr differed from those of cold rolled Ti in that the grain
boundary misorientation distribution and texture were rather stable during grain growth.
Jointly Appointed by the Center for Advanced Aerospace Materials
This article is based on a presentation made in the 2002 Korea-US symposium on the “Phase Transformations of Nano-Materials,”
organized as a special program of the 2002 Annual Meeting of the Korean Institute of Metals and Materials, held at Yonsei
University, Seoul, Korea on October 25–26, 2002. 相似文献