球形破片对对人员的杀伤威力研究

建立了球形破片对避弹衣和人体侵彻的数学模型，并以此为基础提出了新的杀标准，用此新标准计算杀伤面积和进行球形靶实验比较简便，并与战场实际相符。     

二维非规则碎片匹配的算法

提出了一种基于曲率相似性的二维碎片轮廓匹配算法。该算法根据碎片轮廓上各点的曲率值来确定轮廓上的特征点，按照特征点对轮廓进行分段，将二维碎片的匹配简化为特征段的相似性度量与可匹配性验证。对可匹配的轮廓段进行欧氏变换以拼合两个轮廓曲线，自动地检测在当前变换下两个轮廓是否有重叠情况存在。没有重叠的两个轮廓组合起来更新为一个新的轮廓，进行再匹配直至重建过程完成。实例表明，算法是有效、稳定的。     

时基媒体数据分布系统及方法研究

在内容分发网络的系统中,数据分布系统是必要组成部分。在项目研究中的经验和教训基础上,本文提出一种时基媒体数据的分布系统及相关方法（分片数据使用统计方法、历史数据统计挖掘预测方法、分布策略的产生方法）,并给出结论和未来工作展望。     

Provenance studies of archaeological ceramics from Mar-Takla(Ain-Minin,Syria)using radioisotope X-ray fluorescence method

The radioisotope X-ray fluorescence method was applied to studies of the provenance of the ceramics fragments originated from the Mar-Takla site in Syria.The samples were irradiated 1000s by a ^109Cd radioisotope source and 13 elements (Ca,Ti,Mn,Fe,Zn,Ga,As,Rb,Sr,Y,Zr,Nb,and Pb)were determined in 35 samples.The data were subjected to two multivariate statistical methods,cluster and principal components analysis(PCA).It was shown from the combination of the statistical techniques and the determination of elemental composition of the samples that 94% of the ceramic samples analyzed can be considered to be manufactured using two sources of raw materials.     

Video fragment format classification using optimized discriminative subspace clustering

All video streams consist of highly compressed coded data. A video stream must be decoded to identify a video. It is impossible to decode and identify a video fragment without knowing the correct video format. Therefore, the first issue that must be addressed is classification of video formats. Although several methods exist for classifying file formats, a technology that specifically classifies the formats of video fragments has not been developed. In this paper, we present a novel approach to classify the formats of small fragments of video streams. Our classification procedure involves construction of high-dimensional feature vectors by combining synchronization patterns extracted from training fragments. The feature vectors are classified using optimized discriminative subspace clustering (ODiSC). The experimental results show a minimum classification error rate of 4.2%, and the precision of identification of the formats was greater than 91% for the four video formats whose fragment size was 256 KB.     

NUMERICAL SIMULATION OF ROCK BREAKING MECHANISM WITH HIGH-PRESSURE WATER JET

Based on the analysis of experimental results.the rock damage model and the damage coupling model suitable for the whole rock breaking process with water jet were established with continuous damage mechanics and micro damage mechanics, and the numerical method was developed with continuum mechanics and the FEM theory. The rock breaking mechanism with water jet was studied systematically with numerical simulation for the first time in the field of water-jet rock breaking. The numerical results agree with the experimental ones which shows that the presented method is reasonable and can reflect the reality of water-jet rock breaking. The conclusion can be applied in practice.     

HPLC-Q-TOF MS鉴定条叶榕根茎乙酸乙酯提取物中的主要化学成分

采用高效液相色谱-四极杆飞行时间质谱(HPLC-Q-TOF MS)技术对条叶榕根茎乙酸乙酯提取物中的多种活性化学组分进行了分析鉴定。采用正离子与负离子两种扫描方式,依据高分辨质谱提供的准分子离子峰和碎片离子的精确分子质量信息,确证了有关物质及其特征碎片离子的分子组成。再结合标准品对照与相关文献数据支持,最终鉴定出条叶榕根茎乙酸乙酯提取物中的34种化学成分,其中包括12种多酚、8种香豆素、9种黄酮、4种脂肪酸、1种蒽醌。结果表明,采用HPLC-Q-TOF MS技术可提高中药化学成分的分析效率,有利于新化合物的发现与鉴别。     

基于BP 神经网络的破片聚焦曲线优化

为解决战斗部预制破片的飞散方向控制这个复杂的非线性问题,基于大量试验和仿真数据,应用BP 神经 网络技术对破片飞散方向修正设计量进行预测,建立破片聚焦曲线优化设计系统,可对传统解析模型设计的破片聚 焦曲线进行自动优化。试验结果表明：优化后的聚焦曲线具有较高的破片聚焦效率,可有效减少破片聚焦曲线迭代 的试验次数。     

某杀爆战斗部破片与冲击波运动规律研究

通过对某杀爆战斗部爆炸后破片运动及冲击波传播的研究,理论推导了破片与冲击波相遇位置的求解全过程。采用Visual C++开发破片与冲击波运动规律计算系统,并用数值积分方法对冲击波速度与位移进行分段积分。通过该系统计算了某预制破片战斗部破片与冲击波的相遇位置,并运用 ANSYS/LS-DYN数值模拟了该预制破片战斗部爆炸后破片与冲击波的运动,数值模拟结果与计算结果基本相符。     

One Question,Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

Fragment‐based lead discovery is gaining momentum in drug development. Typically, a hierarchical cascade of several screening techniques is consulted to identify fragment hits which are then analyzed by crystallography. Because crystal structures with bound fragments are essential for the subsequent hit‐to‐lead‐to‐drug optimization, the screening process should distinguish reliably between binders and non‐binders. We therefore investigated whether different screening methods would reveal similar collections of putative binders. First we used a biochemical assay to identify fragments that bind to endothiapepsin, a surrogate for disease‐relevant aspartic proteases. In a comprehensive screening approach, we then evaluated our 361‐entry library by using a reporter‐displacement assay, saturation‐transfer difference NMR, native mass spectrometry, thermophoresis, and a thermal shift assay. While the combined results of these screening methods retrieve 10 of the 11 crystal structures originally predicted by the biochemical assay, the mutual overlap of individual hit lists is surprisingly low, highlighting that each technique operates on different biophysical principles and conditions.