首页 | 官方网站   微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3387篇
  免费   133篇
  国内免费   19篇
医药卫生   3539篇
  2024年   15篇
  2023年   111篇
  2022年   93篇
  2021年   128篇
  2020年   121篇
  2019年   128篇
  2018年   139篇
  2017年   96篇
  2016年   52篇
  2015年   58篇
  2014年   187篇
  2013年   191篇
  2012年   147篇
  2011年   187篇
  2010年   178篇
  2009年   123篇
  2008年   150篇
  2007年   128篇
  2006年   125篇
  2005年   95篇
  2004年   127篇
  2003年   130篇
  2002年   131篇
  2001年   92篇
  2000年   87篇
  1999年   95篇
  1998年   96篇
  1997年   52篇
  1996年   59篇
  1995年   54篇
  1994年   60篇
  1993年   16篇
  1992年   6篇
  1991年   5篇
  1990年   2篇
  1989年   6篇
  1988年   2篇
  1987年   2篇
  1986年   9篇
  1985年   14篇
  1984年   4篇
  1983年   5篇
  1982年   4篇
  1981年   10篇
  1980年   4篇
  1979年   5篇
  1978年   2篇
  1977年   1篇
  1976年   1篇
  1975年   6篇
排序方式: 共有3539条查询结果,搜索用时 0 毫秒
61.
目的了解烧伤科护士负性工作情感体验和应对方法 ,提出相应解决对策。方法对67名烧伤科护士进行访谈,用Claizzi资料分析法对访谈资料进行分析。结果烧伤科护士负性工作情感体验中提炼出3个主题:工作压力大、心理负荷重、工作环境紧张,护士对负性情绪的应对方法局限。结论护理管理者应重视烧伤科护理人员的情感,合理配置护理人力资源,创造和谐的工作环境,以稳定护理队伍。  相似文献   
62.
Recent studies have shown that vagus nerve stimulation (VNS) can block the burn-induced systemic inflammatory response (SIRS). In this study we examined the potential for VNS to modulate vascular permeability (VP) in local sites (i.e. skin) and in secondary sites (i.e. lung) following burn. In a 30% total body surface area burn model, VP was measured using intravascular fluorescent dextran for quantification of the VP response in skin and lung. A peak in VP of the skin was observed 24 h post-burn injury, that was blocked by VNS. Moreover, in the lung, VNS led to a reduction in burn-induced VP compared to sham-treated animals subjected to burn alone. The protective effects of VNS in this model were independent of the spleen, suggesting that the spleen was not a direct mediator of VNS. These studies identify a role for VNS in the regulation of VP in burns, with the translational potential of attenuating lung complications following burn.  相似文献   
63.
目的:探讨综合护理在烧伤治疗中应用的临床意义,总结更为有效的烧伤护理方法。方法随机将78例Ⅱ度烧伤患者分为两组,每组39例。以在治疗过程中接受常规护理者为常规组,以在治疗过程中接受综合护理者为综合组,对比两组治疗效果及并发症发生率。结果综合组1周皮肤愈合率及2周皮肤愈合率分别为(75.12±7.16)%及(90.12±6.67)%均明显高于常规组的(60.23±7.23)%及(82.16±7.71)%;同时综合组皮肤愈合时间明显为(8.27±1.37)d短于常规组的(12.16±2.26)d(P<0.05);同时综合组治疗总有效率明显高于常规组(P<0.05),而两组并发症发生率比较未见统计学差异(P>0.05)。结论综合护理可有效的提高烧伤患者的治疗效果,且并不增加并发症发生率。  相似文献   
64.

Objective

To develop self-reported short forms for the Life Impact Burn Recovery Evaluation (LIBRE) Profile.

Design

Short forms based on the item parameters of discrimination and average difficulty.

Setting

A support network for burn survivors, peer support networks, social media, and mailings.

Participants

Burn survivors (N=601) older than 18 years.

Interventions

Not applicable.

Main Outcome Measures

The LIBRE Profile.

Results

Ten-item short forms were developed to cover the 6 LIBRE Profile scales: Relationships with Family & Friends, Social Interactions, Social Activities, Work & Employment, Romantic Relationships, and Sexual Relationships. Ceiling effects were ≤15% for all scales; floor effects were <1% for all scales. The marginal reliability of the short forms ranged from .85 to .89.

Conclusions

The LIBRE Profile-Short Forms demonstrated credible psychometric properties. The short form version provides a viable alternative to administering the LIBRE Profile when resources do not allow computer or Internet access. The full item bank, computerized adaptive test, and short forms are all scored along the same metric, and therefore scores are comparable regardless of the mode of administration.  相似文献   
65.

Background

Insulin, as an anti-inflammatory drug, could not be freely used in patients who experienced trauma according to the degree of inflammation, because of the side effect of hypoglycemia. In vivo experimental evidence is lacking concerning whether the effect is dosage dependent and whether it relies on controlling hyperglycemia.

Methods

By adjusting the dosage ratio of glucose and insulin, different dosages of insulin were used to treat severely scalded MODS rats to achieve uncontrolled or controlled hyperglycemia. One hundred forty rats with severe scalded were randomly divided into a hyperglycemia-controlled group, hyperglycemia-uncontrolled group, and control group. The levels of inflammation response indexes and major organ dysfunction indexes were measured and compared between groups.

Results

The blood indexes of inflammatory response and major organ dysfunction did not show statistical difference between hyperglycemia-controlled groups (A) and uncontrolled groups (B) in the same dosage of insulin (all P > 0.05). The blood indexes of inflammatory response and major organ dysfunction demonstrated statistical difference in different dosages of insulin with hyperglycemia-controlled groups (A1–A3 groups) and hyperglycemia-uncontrolled groups (B1–B3 groups) (all P < 0.01). The higher dosage of insulin, the better effect of anti-inflammation and organ protection it would demonstrate with or without controlling hyperglycemia.

Conclusions

The effect of anti-inflammation and organ protection of insulin is dosage dependent in vivo; it does not rely on controlling hyperglycemia. Temporary traumatic hyperglycemia itself might not be detrimental to the body. Adjusting the ratio of insulin and glucose could provide a novel train of thought for freely treating patients with severe traumatic injury with different dosages of insulin according to the degree of inflammation.  相似文献   
66.

Background

Little data is available in the literature about the role of end tidal oxygen in critically ill patients. We sought to identify the association between the level of respiratory oxygen and clinical outcomes in critically-ill ventilated trauma and burn patients.

Methods

A retrospective cohort of 55 trauma and burn patients from 2010 to 2016 was collected. Exposures of interest included a) expiratory end tidal oxygen (ETO2) and b) the difference between FiO2 and ETO2 (uptake). Associations of clinical characteristics with ETO2 and oxygen uptake were examined using a Spearman correlation. The relationships between discharge status, demographics, injury type, severity, and clinical characteristics were examined using chi-square (or Fisher's exact) tests and two-sample t-tests. Multivariable analyses using linear and logistic regression were performed to determine whether expiratory end tidal oxygen or oxygen uptake was an independent predictor of clinical outcomes.

Results

Mean age for the patients was 46.3 ± 18.2 years with 41 (74.6%) male and 34 (61.8%) white. In the cohort, 27 (49.1%) of patients had burns and 28 (50.9%) blunt trauma. Oxygen uptake was negatively correlated with lactic acid, minute ventilation, total ICU days, and ventilator days (p < 0.05). Patients who died demonstrated lower oxygen uptake than those alive, oxygen uptake remained significantly associated with discharge status after adjusting for potential confounders (p = 0.028).

Conclusion

A narrowed difference between ETO2 and inspiratory oxygen is associated with increased mortality in a cohort of ventilated trauma and burn patients. Future research is needed to further elucidate the role of respiratory oxygen level in larger, prospective studies.  相似文献   
67.
大面积烧伤患者并发应激性溃疡出血较常见,该文报道1例在烧伤20余日后呕吐暗红色长条索状物质的患者,行急诊胃镜检查可见食管全段至胃幽门部黏膜充血明显,大量鲜红色血性液,于食道中下段见大片黏膜脱落,考虑诊断为应激性溃疡出血、食管管型。长条索状物质送检后病理证实为混合性血栓,未见明确胃食管黏膜。该例烧伤患者并发应激性溃疡出血后呕吐暗红色长条索状物质,临床表现极为罕见。该文针对误诊和出现特殊临床表现的原因进行分析,旨在供广大临床医务人员共同学习,加强对烧伤后应激性溃疡出血预防的重视,减少误诊,提高早期发现、诊治该病在特殊异常情况下的能力。  相似文献   
68.
69.
70.
Burn wound care today has a primary objective of temporary or permanent wound closure. Commercially available engineered alternative tissues have become a valuable adjunct to the treatment of burn injuries. Their constituents can be biological, alloplastic or a combination of both. Here the authors describe the aspects of the development of a siloxane epidermis for a collagen‐glycosaminoglycan and for nylon‐based artificial skin replacement products. A method to fabricate an ultra‐thin epidermal equivalent is described. Pores, to allow the escape of wound exudate, were punched and a tri‐filament nylon mesh or collagen scaffold was imbedded and silicone polymerisation followed at 120°C for 5 minutes. The ultra‐structure of these bilaminates was assessed through scanning electron microscopy. An ultra‐thin biomedical grade siloxane film was reliably created through precision coating on a pre‐treated polyethylene terephthalate carrier.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司    京ICP备09084417号-23

京公网安备 11010802026262号