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排序方式: 共有6347条查询结果,搜索用时 15 毫秒
101.
102.
Karol MalechaAuthor Vitae Dorota G. PijanowskaAuthor VitaeLeszek J. GolonkaAuthor Vitae Piotr KurekAuthor Vitae 《Sensors and actuators. B, Chemical》2011,155(2):923-929
This article presents design, fabrication and testing of a miniature ceramic-based biosensor which is destined for continuous glucose monitoring. It is fabricated using well known LTCC (low temperature co-fired ceramics) technology. The biosensor consists of a microreaction chamber, three thick-film electrodes and a microdialysis tube. The detection process is based on oxidation of glucose by molecular oxygen in the presence of enzyme - glucose oxidase, GOx. One of the reaction products is a hydrogen peroxide which is detected amperometrically during its oxidation at a working electrode. Computational fluid dynamics (CFD) analysis was used for optimization of the biosensor geometry and considerations of the influence of operating conditions (flow rate) on mass transfer (diffusion) of the glucose within the microreaction chamber. Tests of the developed LTCC-based biosensor indicate its linear response to glucose concentration up to 9 mM with a relatively high sensitivity of about 147 nA/mM. Moreover, the properties of the presented ceramic biosensor are compared with properties of a similar device made in silicon/glass and in Perspex®. 相似文献
103.
MEMS流量控制系统中,需要微型化的流量传感器,设计了一种反馈流驱动的微尺度射流流量计.采用数值模拟的方法对微尺度射流流量计进行研究,CFD软件的仿真结果表明:在较宽入口速度范围内该微尺度射流流量计起振快,振荡稳定,切换灵敏,斯特劳哈尔数基本恒定,并且流速测量下限可以达到0.075 m/s,在一定程度上为射流流量计的微... 相似文献
104.
105.
《计算机应用与软件》2016,(12)
基于CFD数值模拟技术系统地研究了静态混合器对改善SCR脱硝系统首层催化剂入口截面速度/浓度均匀分布特性的作用规律。数值计算结果表明,针对特定的静态混合器型式,优化前后速度/浓度分布偏差最大改善量分别为8.89%、12.26%,系统整体压损最大升高量约为188 Pa。因此认为静态混合器的优化布置可以显著改善截面内的速度/浓度均匀分布特性,但基于系统压损呈现的变化规律,建议在进行静态混合器设计时需综合权衡速度/浓度分布偏差改善性能与系统整体压损变化特性两方面的因素。 相似文献
106.
为提高摆线泵的容积效率,优化泵内部的流场分布,减少回流和空化现象.利用CFD方法对摆线泵内部流场进行数值模拟,定量分析月牙状进出油腔对泵容积效率的影响.仿真结果表明,适当减小G0并增大F0可以改善泵的内部流场分布,提高容积效率.仿真结果可以为摆线泵的结构设计提供参考. 相似文献
107.
108.
Christoph Bosshard Roland Bouffanais Michel Deville Ralf Gruber Jonas Latt 《Computers & Fluids》2011,44(1):1-8
In this paper, a comprehensive performance review of an MPI-based high-order three-dimensional spectral element method C++ toolbox is presented. The focus is put on the performance evaluation of several aspects with a particular emphasis on the parallel efficiency. The performance evaluation is analyzed with the help of a time prediction model based on a parameterization of the application and the hardware resources. Two tailor-made benchmark cases in computational fluid dynamics (CFD) are introduced and used to carry out this review, stressing the particular interest for clusters with up to thousands of cores. Some problems in the parallel implementation have been detected and corrected. The theoretical complexities with respect to the number of elements, to the polynomial degree, and to communication needs are correctly reproduced. It is concluded that this type of code has a nearly perfect speedup on machines with thousands of cores, and is ready to make the step to next-generation petaFLOP machines. 相似文献
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110.
Design optimization of an enzymatic assay in an electrokinetically-driven microfluidic device 总被引:1,自引:1,他引:0
Y. T. Atalay P. Verboven S. Vermeir N. Vergauwe F. Delport B. M. Nicolaï J. Lammertyn 《Microfluidics and nanofluidics》2008,5(6):837-849
Microfluidic systems are increasingly popular for rapid and cheap determinations of enzyme assays and other biochemical analysis.
In this study reduced order models (ROM) were developed for the optimization of enzymatic assays performed in a microchip.
The model enzyme assay used was β-galactosidase (β-Gal) that catalyzes the conversion of Resorufin β-d-galactopyranoside (RBG) to a fluorescent product as previously reported by Hadd et al. (Anal Chem 69(17): 3407–3412, 1997). The assay was implemented in a microfluidic device as a continuous flow system controlled electrokinetically and with a
fluorescence detection device. The results from ROM agreed well with both computational fluid dynamic (CFD) simulations and
experimental values. While the CFD model allowed for assessment of local transport phenomena, the CPU time was significantly
reduced by the ROM approach. The operational parameters of the assay were optimized using the validated ROM to significantly
reduce the amount of reagents consumed and the total biochip assay time. After optimization the analysis time would be reduced
from 20 to 5.25 min which would also resulted in 50% reduction in reagent consumption. 相似文献