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BaiHang Chen Chao Chen ZeTian Yang PeiZhen Huang Hang Dong ZhanPeng Zeng 《Foot and Ankle Surgery》2019,25(1):63-70
Background
To compare the efficacy between fixation with suture-button and screw in the treatment of syndesmotic injuries: a meta-analysis.Methods
We comprehensively searched PubMed, Embase, and the Cochrane Library and performed a meta-analysis of randomized controlled trials (RCTs) and retrospective comparative studies (RTCs). We performed using Review Manager 5.2.Results
Three RCTs and six retrospective studies were conducted, including a total of 397 patients. The significant differences of the fixation of suture-button were reported for AOFAS scores (at 3, 6 and 12 months follow-up), full-weight time, reoperation, malreduction and the rate of failure of fixation. There were no significant differences between the groups regarding complications of infection, VAS, OMAS, range of motion, TFCS, TFO and MCS.Conclusions
Neither the functional outcome nor complications significantly differed between the fixation methods, but suture-button might lead to a quicker return to work. This analysis needs to be confirmed and updated by larger sample data and rigorously designed RCTs. 相似文献55.
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Mark R. Tonelli MD 《Journal of evaluation in clinical practice》2012,18(5):962-967
While the critical appraisal of clinical research has generally focused on aspects of study design and statistical analysis, other features of clinical studies appear to be more important to clinicians for assessing the value of a particular study in the care of particular patients. These features relate to the quality of the knowledge derived from the research, the value of the results to the care of individual patients, and the responsibility of clinicians to be stewards of limited resources. Twelve features of clinical research studies that affect how compelling individual clinicians find the results are proposed and examined here. By better understanding what makes clinical research compelling enough to alter or reinforce clinical practice, clinical researchers can design future studies to better serve the needs of clinicians and patients. 相似文献
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K. Okuno K. Sato T. Arisaka K. Hosohama M. Gotoh H. Taga Y. Sasao S. Hamada 《Journal of oral rehabilitation》2014,41(7):542-554
Oral appliances (OAs) have demonstrated efficacy in treating obstructive sleep apnea (OSA), but many different OA devices are available. The Japanese Academy of Dental Sleep Medicine supported the use of OAs that advanced the mandible forward and limited mouth opening and suggested an evaluation of their effects in comparison with untreated or CPAP. A systematic search was undertaken in 16 April 2012. The outcome measures of interest were as follows: Apnea Hypopnea Index (AHI), lowest SpO2, arousal index, Epworth Sleepiness Scale (ESS), the SF‐36 Health Survey. We performed this meta‐analysis using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system. Five studies remained eligible after applying the exclusion criteria. Comparing OA and control appliance, OA significantly reduced the weighted mean difference (WMD) in both AHI and the arousal index (favouring OA, AHI: ?7·05 events h?1; 95% CI, ?12·07 to ?2·03; P = 0·006, arousal index: ?6·95 events h?1; 95% CI, ?11·75 to ?2·15; P = 0·005). OAs were significantly less effective at reducing the WMD in AHI and improving lowest SpO2 and SF‐36 than CPAP, (favouring OA, AHI: 6·11 events h?1; 95% CI, 3·24 to 8·98; P = 0·0001, lowest SpO2: ?2·52%; 95% CI, ?4·81 to ?0·23; P = 0·03, SF‐36: ?1·80; 95% CI, ?3·17 to ?042; P = 0·01). Apnea Hypopnea Index and arousal index were significantly improved by OA relative to the untreated disease. Apnea Hypopnea Index, lowest SpO2 and SF‐36 were significantly better with CPAP than with OA. The results of this study suggested that OAs improve OSA compared with untreated. CPAP appears to be more effective in improving OSA than OAs. 相似文献
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Matheus Frana Perazzo Ana Luisa Caldas Otoni Matheus Silva Costa Ana Flvia Granville‐Granville Saul Martins Paiva Paulo Antnio Martins‐Júnior 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2019,29(6):692-711