A proteome analysis of the dorsolateral prefrontal cortex in human alcoholic patients

Alcoholic patients commonly experience cognitive decline. It is postulated that cognitive dysfunction is caused by an alcohol-induced region-selective brain damage, particularly to the prefrontal region, and grey and white matter may be affected differently. We used a proteomics-based approach to compare protein expression profiles of the dorsolateral prefrontal cortex (Brodmann area 9 (BA9)) from human alcoholic and healthy control brains. Changes in the relative expression of 110 protein 'spots' were identified in the BA9 grey matter, of which 54 were identified as 44 different proteins. In our recent article, 60 protein spots were differentially expressed in the BA9 white matter and 18 of these were identified (Alexander-Kaufman, K., James, G., Sheedy, D., Harper, C., Matsumoto, I., Mol. Psychiatry 2006, 11, 56-65). Additional BA9 white matter proteins are identified here and discussed in conjunction to our grey matter results. Thiamine-dependent enzymes transketolase and pyruvate dehydrogenase (E1β ubunit) were among the proteins identified. To our knowledge, this is the first time a disruption in thiamine-dependent enzymes has been demonstrated in the brains of 'neurologically uncomplicated' alcoholics. By identifying protein expression changes in prefrontal grey and white matter separately, hypotheses may draw upon more mechanistic explanations as to how alcoholism causes the structural alterations associated with alcohol-related brain damage and cognitive dysfunction.     

正交调幅数字系统

文章分析了存在载波相位起伏、正弦干扰、高斯白噪声时正交调幅数字系统的抗扰性。结果表明,当接收载波相位起伏低于0.5度时,16QAM达最佳。     

金融危机触发白色家电企业发展客户关系管理新契机

金融危机使得整个家电行业都受到了严重的冲击,白色家电企业更是面临着原材料涨价、市场饱和、利润缩水等困境。本文首先论述了金融危机对白色家电企业的影响,然后提出了客户关系管理的应对出路。针对白色家电企业的特点,着重论述了企业实施CRM基本目标、基本框架以及实施后的功能效果等问题,为白色家电企业找到新的利润增长点、走出金融危机、成功实现＂V＂型反转提供了有价值的参考。     

瑞利信道下线性分组码的分集增益研究

比较AWGN信道与瑞利信道的误码性能,研究瑞利信道下分集支数与信息传输可靠性之间的关系。推导线性分组码在瑞利信道下误码率上界的理论表达式,得到分集增益与其最小汉明距离的关系。基于蒙特卡洛法对误码性能进行仿真,并与理论误码率上界进行比较,结果表明线性分组码在瑞利信道下获得的分集增益等于其最小码距。     

In-plane directional mechanical properties of carbon fabric skins in sandwich structures after thermoforming

In this paper, a representative unit volume finite element (RUV FE) model was employed to simulate thermoforming process of carbon fabric-polymeric foam sandwich structures. Thermoforming simulations, which capture crimp angles and amplitude changes of carbon fabric with respect to different operational pressure, were conducted with the help of RUV FE model. Micro-deformation of tow structures after thermoforming was rigorously reflected in the second stage FE model to determine the in-plane directional stiffness of skin parts. Tensile tests were carried out to investigate mechanical properties of skin parts in sandwich structures for the potential usage of automotives, electronic housings or the satellite structure design.     

White organic light-emitting diodes from three emitter layers

Three-wavelength white organic light-emitting diodes (WOLEDs) were fabricated using two doped layers, which were obtained by separating the recombination zones into three emitter layers. A sky blue emission originated from the 4,4′-bis(2,2′-diphenylethen-1-yl)biphenyl (DPVBi) layer. A green emission originated from a tris(8-quinolinolato)aluminum (III) (Alq₃) host doped with a green fluorescent 10-(2-benzothiazolyl)-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H,5H,11H-[1]benzopyrano [6,7,8-ij]-quinolizin-11-one (C545T) dye. An orange emission was obtained from the N,N′-bis(1-naphthyl)-N,N′-diphenyl-1,1′-biphenyl-4,4′-diamine (NPB) host doped with a red fluorescent dye, 4-(dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB). A white light resulted from the partial excitations of these three emitter layers by controlling the layer thickness and concentration of the fluorescent dyes in each emissive layer simultaneously. The electroluminescent spectrum of the device was not sensitive to the driving voltage of the device. The white light device showed a maximum luminance of approximately 53,000 cd/m². The external quantum and power efficiency at a luminance of approximately 100 cd/m² were 2.62% and 3.04 lm/W, respectively.     

旧料生产锡磷青铜带材急冷破鳞开裂原因及其探讨

阐述了在实际生产过程中，因大量使用镀白旧料生产锡磷青铜带材，在急冷破鳞时易出现开裂现象及其产生的原因。根据其特有的生产工艺及特点提出了相应的解决方法。     

现代锡磷青铜带材生产工艺与技术

锡磷青铜带是当前应用最广泛的铜合金弹性材料。电子、通讯和汽车行业的高速发展，接插件、连接器用的锡磷青铜带材需用量剧增，质量上要求高精度、高表面、优良的板型和严格的性能值。该文就现代锡磷青铜带材生产的熔炼与铸造、退火、轧制、清洗、矫平、剪切等工艺与技术作一介绍。     

Characterization of (Y,Gd) BxV1-xO4-x:Eu Phosphor Prepared by Coprecipitation Reaction

White body-color (Y, Gd)BxV1- xO4-x :Eu3 phosphors were prepared by coprecipitation reaction. Under VUV excitation at 147 nm, the red emission colorimetric purity of (Y, Gd)BxV1- xO4-x :Eu3 phosphor is much better than that of commercial PDP (plasma display panels) phosphor (Y, Gd)BO3:Eu3 . But its relative emission intensity is only about 90% of the commercial phosphor.     

Sol-Gel Synthesis and Luminescent Characteristic of Doped Eu^3 ＋ Silicate-Silica Phosphor

Silicagelphosphorsdopedrareearthionshave attractedgreatattentionofmanyresearchersdueto theseadvantages,suchashighersamplehomogeneity,purityandstable,efficientandenvironmentallyfriend lyphotoluminescencematrixmaterials,whichisless toxicleadtonetconversione…