刃厚皮片联合微型带真皮下血管网全厚皮片修复截瘫褥疮

目的：应用刃厚皮片联合微型真皮下血管网全厚皮片修复截瘫褥疮。方法：对6例截瘫褥疮，增强全身支持治疗，彻底清除褥疮的炎性肉芽组织及坏死组织后，采用刃厚皮片联合微型真皮下血管网全厚皮片修复．结果：5例Ⅰ期愈合，1例Ⅱ期愈合。结论：本法操作简单，愈合较快，具有一定的耐磨性，为进一步皮瓣修复奠定了基础，是修复难治性截瘫褥疮较理想的方法．     

兔肢体爆炸伤合并海水浸泡后在不同复温速率及维持浅低体温下机体炎症反应的特征

Objective To investigate effects of different rewarming rates and maintenance of light hypothermia on inflammatory response in rabbits after limb blast injury, coupled with seawater immersion. Methods First, the model of limb blast injury coupled with seawater immersion was reproduced [the animals were immersed to low body temperature of (31.0±0.5℃)]. Then, 24 adult rabbits were randomly divided into group Ⅰ [the rapid rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (8.94±0.93)℃/h], group Ⅱ [the slow rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (3.88±0.22)℃/h], group Ⅲ [another slow rewarming group, n=6, rewarmed to (38±0.5)℃ at a rate of (2.18±0.12)℃/h], and the H group [the hypothermia group, n =6, rewarmed to (34 - 35)℃ at a rate of (4.49±0.66)℃/h and kept at that temperature till termination of the experiment]. Regulation of ambient temperature and warm transfusion were used to restore body temperature to target levels and maintained there for 6 hours. Blood samples were taken at 5 different times, I.e. Pre-injury time(T0), post-immersion time (T1), the time when rewarming started (T2), 3 h after rewarming (T3), and 6 h after rewarming (T4). Tissue samples from heart, liver, intestinum, lung and kidney were also collected. Levels of TNF-α (tumor necrosis factor-α), IL-1β (interleukin-1β) and IL-6 (interleukin-6) in plasma and MPO (myeloperoxidase) in homogenate were detected. Results Following rewarming, TNF-α, IL-1β, IL-6 concentrations in the plasma of the animals in group Ⅰ and group H were significantly higher when compared with those of the animals in group Ⅱ and group Ⅲ (P<0.05, P<0.01), and MPO activity in homogenate was significantly higher when compared with that of the animals in group Ⅱ and group Ⅲ(P<0.01, P<0.05), and no statistical difference could be seen between group Ⅱ and Ⅲ (P>0.05). Conclusions Rapid rewarming and maintenance of light hypothermia could obviously elevate TNF-α, IL-1β, IL-6 concentrations in plasma and MPO activity in homogenate, following limb blast injury coupled with hypothermia induced by seawater immersion, while slow rewarming (with a rewarming rate of 2-4℃/h) could significantly inhibit TNF-α, IL-1β, IL-6 levels and PMN activity.     

survivin、P53蛋白在非小细胞肺癌的表达及其相关性研究

目的 :研究survivin、P5 3蛋白在非小细胞肺癌 (NSCLC)组织的表达及其生物学意义 ,并探讨其相关性。　方法 :用免疫组化 (S P法 )染色技术对 95例NSCLC组织石蜡标本进行survivin、P5 3蛋白表达的检测和分析。　结果 :survivin、P5 3在肺癌细胞中阳性表达率 (6 2 .1 %、5 5 .8% )明显高于癌旁的正常肺组织 (1 4 %、7% ) (P <0 .0 1 )。survivin的表达与肿瘤病理分级、组织学分型、淋巴结转移、TNM分期无明显相关 (P >0 .0 5 ) ;P5 3表达与淋巴结转移相关 (P <0 .0 5 ) ,而与肿瘤病理分级、组织学分型、TNM分期无明显相关 (P >0 .0 5 ) ;此外 ,survivin与P5 3蛋白的表达呈显著正相关 (r =0 .5 72 ,P <0 .0 1 )。　结论 :凋亡抑制蛋白survivin与突变型P5 3蛋白在NSCLC的发生发展中可能起协同作用 ,也提示抑癌基因p5 3(野生型 )可能对survivin的表达起负反馈调节作用。survivin和P5 3蛋白可作为靶点用于NSCLC靶向治疗的研究     

正常者瞳孔间距与咬合垂直距离关系的研究

目的：研究正常[牙合]者瞳孔间距（Interpupillary Distance，IPD）与咬合垂直距离（Occlusal Vertical Dimension，OVD）的关系。方法：对116名福建籍青年正常[牙合]者测量其OVD与IPD，并进行两者相关回归分析。结果：总样本的OVD均值为65．35mm±4．70mm，IPD均值为63．98mm±3．26mm，男性正常[牙合]者OVD均值为68．16mm±4．23mm，IPD均值为65．46mm±2．96mm，女性正常[牙合]者的OVD均值为63．22mm±3．86mm，IPD均值为62．86mm±3．05mm;总样本的IPD与OVD的相关系数r=0．633，男性样本的IPD与0VD的相关系数r=0．563，女性样本的IPD与OVD的相关系数r=0．531。结论：IPD与OVD间存在显著相关性，IPD可以作为需咬合重建患者确定其OVD的参考指标。     

从人才市场竞争特点看高职英语人才的培养

我国经济全球化趋势给商务英语专业毕业生就业带来了前所未有的机遇，然而近几年高等教育的超常规发展又使得高职生在就业中面临着“上压下挤”的困境。本文对目前影响英语人才就业的多方面因素进行分析，并根据市场竞争特点就高职英语专业如何面对机遇与挑战，因“市”利导，在人才定位和培养机制上走高职特色的发展路子提出建议。     

磁共振波谱分析在脑胶质瘤侵袭边界确定中的应用进展

脑胶质瘤是最常见的颅内肿瘤、局部侵袭是脑胶质瘤的一个显著特征．典型的肿瘤有一个中央坏死灶，周围致密肿瘤细胞区．外绕被肿瘤细胞侵袭的脑组织。手术仍是目前临床上最主要和最基本的治疗方法，在保存正常脑组织的前提下尽可能的切除肿瘤一直是脑胶质瘤手术治疗中应遵循的基本原则。     

脊索瘤的影像学特点分析

目的探讨脊索瘤的影像学表现。方法搜集经手术病理证实的脊索瘤42例,对其影像学表现进行回顾性分析。结果颅底脊索瘤23例(54.8%),骶尾部脊索瘤18例(42.9%),外周脊索瘤1例(2.3%)。平片可见颅底及骶尾部溶骨性骨质破坏;CT扫描脊索瘤特征性地表现为斜坡和骶尾部膨胀性软组织肿块伴相应部位广泛溶骨性骨质破坏;MRI扫描对病变范围的显示优于CT。结论脊索瘤有较为典型的好发部位,MRI表现较具特征性。     

自杀行为及其干预的研究进展

自杀已经成为一个世界范围内的重大公共卫生问题。中国的自杀特征具有独特性。自杀行为的发生往往是内在因素与外部因素相互作用的结果，它与社会学、心理学、伦理学、生物学、精神病学等各方面密切相关。自杀原因虽然错综复杂，但我们要提高意识，认识到自杀是一种可以预防的公共卫生问题。     

基于变更模型的元数据在构件回归测试中的应用研究

本文针对Orso元数据方法的不足,对构件可能的变更进行了充分分析和分类,并按照分类情况对相关的构件变更处理方法进行了详尽的形式化描述,构造了构件变更模型,描述了每个变更的具体表现形式,论述了方法变更到构件接口变更的映射机制和算法,给出了算法实现的框架,并将这些理论模型应用到自主开发的构件RegisterStuGrade中,与没有元数据情况下的回归测试用例生成技术以及Orso方法进行回归测试用例数和回归测试运行时间两方面的分析和对比,给出了比较结果.