两种艾灸法对二肾一夹型高血压大鼠血压和血管内皮细胞内分泌功能的影响

目的:应用两种艾灸疗法治疗两肾一夹肾血管性高血压大鼠(2K1C-RHR),评价这两种艾灸疗法的降压作用,并对其降压机理作初步的探讨。方法:建立2K1C-RHR模型,并将其随机分为六组:灸法Ⅰ组(百会、神阙、足三里)、灸法Ⅱ组(关元、涌泉、足三里)、卡托普利组、灸法Ⅰ+卡托普利组、灸法Ⅱ+卡托普利组、高血压对照组,另设正常对照组。经过10天治疗后,测量血压,并测定血浆中内皮素(ET)、一氧化氮(NO)。结果:高血压对照组的收缩压(SBP)、舒张压(DBP)明显高于正常对照组,各治疗组的SBP、DBP明显低于高血压对照组(P<0.01),各治疗组间则没有明显差异(P>0.05)。血浆NO含量各组间没有明显差异(P>0.05)。各治疗组与正常对照组的血浆中ET含量明显低于高血压对照组(P<0.01)。各治疗组ET/NO比值接近正常对照组(P>0.05)且明显低于高血压对照组(P>0.05)。结论:两种艾灸疗法有良好的降压作用,其降压机理与及纠正ET与NO的失衡状态有关。     

分娩镇痛的临床观察

目的 探讨布比卡因硬膜外自控镇痛和罗湃卡因蛛风膜下腔－硬膜外自控镇痛用于分娩的效果及对产程、母婴的影响。方法 ９０例初产妇分为３组,布比卡因硬膜外自控镇痛组（Ａ组,ｎ＝３０）、罗哌卡因蛛网膜下腔－硬膜外自控镇痛组（Ｂ组,ｎ＝３０）和对照组（Ｃ组,ｎ＝３０,未行分娩镇痛）,观察各组镇痛效果、产程时间、分娩方式血清皮质醇及新生儿Ａｐｇａｒ评分情况。结果 Ａ,Ｂ组镇痛效果满意,以Ｂ组为佳两组 产程未血清     

改良显微小梁切除术治疗葡萄膜炎继发性青光眼

Objective To investigate the effect of trabeculectomy combined with segmental iridectomy, mitomycin C (MMC) and viscoelastic agents usage on the treatment of glaucoma secondary in uveitis. Methods According to the age, degree of inflammation and the condition of Tenon capsule of patients, differ-ent concentration of MMC (0.25-0.33 mg/ml) was used during the operation, with separation of the anterior and posterior synechia, resection of pupillary organization membrane using viscoelastic agents. Segmental iridec-tomy and releasable sutures were also performed on the patients. The visual acuity of preoperation and postoper-ation, intraocular pressure, inflammation and the complication were record. Results Forty-two eyes of 38 cases with glaucoma secondary in uveitis were studied, the mean follow-up time was (12.01±3.56) months. The postoperative visual acuity improved in 14 eyes, didn't change in 28 eyes. The postoperative inflammation of anterior chamber disappeared in 35 eyes, relieved in 7 eyes. And the average postoperative intraocular pres-sure (15.20± 4.64) mmHg was significantly lower than the preoperative intraocular pressure (38.37±12.93) mmHg (t = 8.255, P = 0.000). The total success rate was 92.9%. There were no severe complication. Conclusion Trabeculeetomy combined with MMC, viscoelastic agents usage, separation of anterior and poste-rior syneehia, segmental iridectomy and releasable suture could increase the success rate of operation on pa tients with glaucoma secondary in uveitis, decrease the complication and inflammation reaction of operation, and the recurrence of uveitis.     

肾盂输尿管连接部梗阻的手术治疗

目的 探讨肾盂输尿管连接部梗阻的手术治疗方法。方法 对12例肾盂输尿管连接部梗阻患者全部采取开放手术即连续性例瓣肾盂成形术和离断性肾盂成形术。结果 离断性肾盂成形术效果比连续性肾盂成形术效果好。结论 肾盂输尿管连接部梗阻首选手术方式为离断性成形术。     

小剂量茶碱加入小剂量激素吸入治疗慢性哮喘48例疗效观察

<正> 慢性哮喘患者,一般应根据其病情动态,病情轻重程度和用药情度,选择最佳用药方案,笔者采用小剂量茶碱控释剂和小剂量激素吸入,联合治疗,慢性哮喘,以探讨哮喘治疗的合适途径。1 资料与方法1.1 一般情况 笔者选择48例哮喘患者,男性22例,女性     

改良显微小梁切除术治疗葡萄膜炎继发性青光眼

Objective To investigate the effect of trabeculectomy combined with segmental iridectomy, mitomycin C (MMC) and viscoelastic agents usage on the treatment of glaucoma secondary in uveitis. Methods According to the age, degree of inflammation and the condition of Tenon capsule of patients, differ-ent concentration of MMC (0.25-0.33 mg/ml) was used during the operation, with separation of the anterior and posterior synechia, resection of pupillary organization membrane using viscoelastic agents. Segmental iridec-tomy and releasable sutures were also performed on the patients. The visual acuity of preoperation and postoper-ation, intraocular pressure, inflammation and the complication were record. Results Forty-two eyes of 38 cases with glaucoma secondary in uveitis were studied, the mean follow-up time was (12.01±3.56) months. The postoperative visual acuity improved in 14 eyes, didn't change in 28 eyes. The postoperative inflammation of anterior chamber disappeared in 35 eyes, relieved in 7 eyes. And the average postoperative intraocular pres-sure (15.20± 4.64) mmHg was significantly lower than the preoperative intraocular pressure (38.37±12.93) mmHg (t = 8.255, P = 0.000). The total success rate was 92.9%. There were no severe complication. Conclusion Trabeculeetomy combined with MMC, viscoelastic agents usage, separation of anterior and poste-rior syneehia, segmental iridectomy and releasable suture could increase the success rate of operation on pa tients with glaucoma secondary in uveitis, decrease the complication and inflammation reaction of operation, and the recurrence of uveitis.     

5例骨盆骨折合并伤的的误漏分析

骨盆骨折是我们矿山医院外科的常见病。而骨盆骨折损伤机制往往是高能量的暴力损伤，死亡率高达5％～20％，且其并发症是造成死亡的主要原因。经常有不同程度的合并伤和多发伤，如腹腔内脏器损伤和泌尿系统的损伤，因来诊患者大多数病情严重，临床上非常容易造成误漏诊而直接危及生命。我科自1995年7月～2003年9月共收治26例骨盆骨折患者，     

体表电刺激对硬膜外自控镇痛效应及康复质量的影响

目的研究体表电刺激对硬膜外自控镇痛(PCEA)效应和患者康复质量的影响。方法选择经腹子宫切除术60例,随机分成3组,每组20例。A组:于硬膜外麻醉后切皮前、术后4、8h,体表电刺激仪各刺激30min,术后行PCEA;B组:单纯行术后PCEA;C组(对照组):不用PCEA。术后随访镇痛效果、镇痛药用量、血清皮质醇含量、焦虑情绪和患者不良反应等情况。结果PCEA组镇痛效果满意,明显优于对照组(P<0.01)。A组镇痛药用量少于B组(P<0.01),术后皮质醇浓度下降幅度大于B组。A组术后48h内患者的焦虑发生率明显低于C组。结论复合应用体表电刺激,可增强镇痛效应,改善患者的精神心理状态。     

铜绿假单胞菌与机体相互作用在呼吸道感染中的研究进展

铜绿假单胞菌(PA)是导致急慢性感染非常重要的病原体。PA的发病机制非常复杂,感染的结果取决于细菌表现的致病因素以及机体的反应。现将PA主要的致病因子和机体免疫的重要方面作一综述。