OEC管理模式在门诊手术室中的应用

OEC管理模式，是海尔集团建立的一套成功的管理体系，O表示全方位，E表示每人、每天、每事，C表示控制和清理，即指全方位对每个人每一天所做的每件事进行控制和清理。其本质就是把企业核心目标量化到人，把每一个细小的目标责任落实到每一个员工身上。我科自2009年将OEC管理模式运用到护理管理中，逐步探索出一套OEC护理管理方法，在提高护理质量、患者满意度和护理人员自身工作满意度等方面都有显著效果。     

氯丙嗪单独及与顺铂联合应用对人宫颈癌Hela细胞生长的影响

目的:探讨氯丙嗪(CPZ)和顺铂(DDP)联合应用对人宫颈癌Hela细胞株的体外抑制作用。方法:将氯丙嗪、顺铂单独或联合处理Hela细胞,用MTT法检测细胞增殖的抑制率,流式细胞仪检测细胞周期及凋亡,并于用药后不同时间点观察细胞形态学变化。结果:不同浓度的氯丙嗪对细胞生长均有抑制作用,随药物浓度的增加,抑制作用加强。氯丙嗪和顺铂联合应用后抗增殖作用较单一用药显著增强(P<0.05)。二者均可诱导细胞凋亡,联用凋亡率明显增加,并出现G0/G1期细胞阻滞。结论:氯丙嗪可抑制人宫颈癌Hela细胞的增殖,且对顺铂有协同作用。     

食管癌手术的配合与护理

<正> 痛症是威胁人类生命健康的主要疾病之一。病人住院后,往往表现为焦虑和恐惧。为使病人安全顺利地度过手术期,手术室护士应了解病人心理活动特点,进行熟练的手术配合,减少病人的痛苦,缩短手术时间,现将体会介绍如下。 1 手术前病人的护理 1.1 接病人入手术室时,手术室护士要态度和蔼,富有同情心。使病人感到亲切,并用适当的语言向病人交代术前应当做的准备,如病人是否有假牙或活动的牙,术前解大小便等。目的是增加病人的安全感,使病     

C-反应蛋白与2型糖尿病和代谢综合征的关系探讨

目的：研究血清C-反应蛋白（C-RP）在2型糖尿病和代谢综合征中的变化。方法：测定42例2型糖尿病和45例代谢综合征患者血清CPR含量。并和40例健康对照组比较。结果：2型糖尿病患者血清CPR高于正常对照组（P〈0．01）。代谢综合征患者的血清CPR高于正常对照组（P〈0．01），也高于2型糖尿病组（P〈0．01）。结论：2型糖尿病及代谢综合征患者血清中CPR水平明显增高。     

首例尸体肾移植成功术前准备体会

我院首次成功地为终末期肾脏病（ESRD）病人进行了肾脏移植手术．术前内科的充分准备,对手术的成功及顾后起着重要作用．现将术前准备体会报道如下．l临床资料患者,男,引岁,干部,1996－12·05入院．人院诊断：慢性肾功能衰竭尿毒症期,即ESRD．住院期间行规律血液透析、重组红细胞生成素（EPO）等替代方法治疗,同时治疗并发症,间断输新鲜血．供肾为尸肾（男性;27岁）．选择血型相同（A型）及供受者淋巴细胞毒交叉配合试验（CDC）阴性的供者。按手术预定日期,提前一个月给受者加强营养、补充能量并充分透析,以纠正贫血、出血…     

穴位埋线对单纯性肥胖患者炎症因子及相关指标的影响

目的：观察穴位埋线对单纯性肥胖症患者体重、体质指数、腰围、血清C-反应蛋白、白细胞介素-6、胰岛素等指标的影响,研究穴位埋线治疗单纯性肥胖症的机理。方法：30例单纯性肥胖患者采用穴位埋线方法治疗,观察治疗前、治疗后1周及治疗后4周各指标的变化并观察临床疗效。结果：临床总有效率为80．0％,患者的体重减轻（2．2&#177;0．3）kg,体质指数下降（0．82&#177;0．10）kg／m^2,腰围减少（5．12&#177;0．55）cm,与治疗前比较,差异均有统计学意义（P〈0．001）。血清C-反应蛋白、白细胞介素-6及胰岛素含量治疗前后无明显变化（P〉0．05）。结论：穴位埋线疗法能减轻肥胖患者的体重,降低体质指数及减小腰围,但其作用机理未发现与炎症反应及胰岛素改变有关。     

脑星形细胞瘤中TIP30、VEGF和CD34的表达及其相关性研究

Objective To investigate the expression and relationship of TIP30(HIV-1 Tat interactive protein 2), vascular endothelial growth factor (VEGF) and MVD (detected by CD34) in the angiogenesis of human brain astrocytomas. Methods Expression of TIP30, VEGF and CD34 in 19 cases of normal brain tissue and 71 cases of astrocytoma were immunohistochemically examined with Elivision plus two-step method. Results The positive expression of TIP30 could be seen in cytoplasm of neuroglial cells and neurons of 19 normal brain tissues. The positive expression rate of TIP30 in 71 cases of astrocytoma was 33.80 % (24/ 71). The positive expression rate of TIP30 in astrocytoma of different grades was 52 % for grade Ⅱ, 34.78 % for grade Ⅲ and 13.04 % for grade Ⅳ. The positive expression rate of TIP30 in high grade (Ⅲ+Ⅳ) of astrocytoma was found significantly lower than that in low grade(Ⅱ) (χ2=5.71, P <0.05); The expression of VEGF and MVD detected by CD34 in astrocytomas were higher than that in normal brain tissue and increased as the tumor grade increased; In astrocytoma, the negtive correlation was found between the expression of TIP30 and VEGF (r=-0.428, P<0.05); no correlation was found between TIP30 and MVD(r=-0.065, P 0.05); the positive correlation was found between VEGF and MVD(r=0.684, P<0.01). Conclusion The positive expression rate of TIP30 in normal brain tissue is significantly higher than that in astrocytoma. The positive expression rate of TIP30 significantly decreases as the pathological grade of the astrocytoma increases; The expression of TIP30 and VEGF is negatively correlated in astrocytoma.     

妇女更年期心血管系统失调的护理

1妇女更年期心血管系统失调的表现1.1潮红潮红是血管舒张和收缩失调引起的一种症状。患者突感胸部压迫感，心悸，有时眼前发黑，然后感到一阵潮热，自下而上涌向头部，颜面潮红出汗。有的患者则怕冷或阵发性出汗而不伴随潮红。潮红发作的频率及延续时间因人而异。     

脑星形细胞瘤中TIP30、VEGF和CD34的表达及其相关性研究

Objective To investigate the expression and relationship of TIP30(HIV-1 Tat interactive protein 2), vascular endothelial growth factor (VEGF) and MVD (detected by CD34) in the angiogenesis of human brain astrocytomas. Methods Expression of TIP30, VEGF and CD34 in 19 cases of normal brain tissue and 71 cases of astrocytoma were immunohistochemically examined with Elivision plus two-step method. Results The positive expression of TIP30 could be seen in cytoplasm of neuroglial cells and neurons of 19 normal brain tissues. The positive expression rate of TIP30 in 71 cases of astrocytoma was 33.80 % (24/ 71). The positive expression rate of TIP30 in astrocytoma of different grades was 52 % for grade Ⅱ, 34.78 % for grade Ⅲ and 13.04 % for grade Ⅳ. The positive expression rate of TIP30 in high grade (Ⅲ+Ⅳ) of astrocytoma was found significantly lower than that in low grade(Ⅱ) (χ2=5.71, P <0.05); The expression of VEGF and MVD detected by CD34 in astrocytomas were higher than that in normal brain tissue and increased as the tumor grade increased; In astrocytoma, the negtive correlation was found between the expression of TIP30 and VEGF (r=-0.428, P<0.05); no correlation was found between TIP30 and MVD(r=-0.065, P 0.05); the positive correlation was found between VEGF and MVD(r=0.684, P<0.01). Conclusion The positive expression rate of TIP30 in normal brain tissue is significantly higher than that in astrocytoma. The positive expression rate of TIP30 significantly decreases as the pathological grade of the astrocytoma increases; The expression of TIP30 and VEGF is negatively correlated in astrocytoma.