脑智通胶囊与脑复活对血管性痴呆患者智能及血浆降钙素基因相关肽作用的比较

目的:观察中药脑智通胶囊对血管性痴呆患者血浆中有强烈舒血管作用的神经肽降钙素基因相关肽的影响,以及对患者智能改善的作用,并与脑复活进行阳性对照。方法:选择2004-01/09黑龙江中医药大学附属第一医院收治的血管性痴呆患者52例。将患者按随机数字表分为脑智通组和脑复活组各26例,脑智通组口服脑智通胶囊(人参、黄芪、黄精、三七组成),4粒/次(1.975g/粒),3次/d;脑复活组口服脑复活片,4片/次,3次/d,两组均连续用药60d。治疗前后采用放射免疫法分别测定两组患者血浆中降钙素基因相关肽浓度,并观察患者治疗后智能改善情况。结果:按意向处理分析,52例患者全部进入结果分析。①血浆降钙素基因相关肽水平:两组治疗后均较治疗前升高(P<0.05),脑智通组治疗后高于脑复活组[(81.83±6.84),(65.23±10.82),P<0.05]。②临床疗效:脑智通组和脑复活组总有效率无差异(81%,73%,P>0.05),但显效率脑智通组高于脑复活组(35%,12%,P<0.05)。结论:脑智通胶囊通过升高降钙素基因相关肽,能扩张脑血管,增加脑血流量,促进神经细胞的能量代谢,使脑神经细胞功能再恢复,从而改善血管性痴呆患者学习记忆功能,效果优于脑复活。     

肝移植术后患者呼吸机相关性肺炎的影响因素及护理

目的探讨肝移植术后呼吸机相关性肺炎(ventilator associated pneumonia,VAP)的临床及病原学特点。方法对2003年9月至2006年8月实施肝移植术后进行机械通气治疗的136例患者调查分析。结果52例患者出现VAP,发生率为38.23%,病死率为34.61%;88.46%的VAP发生在术后4d之后;病原菌以革兰阴性菌为主,占84.38%。结论肝移植术后患者应用机械通气治疗过程中,针对VAP发生的危险因素,采取积极有效的防治措施,对控制感染、降低病死率有着非常重要的意义。     

肝移植术后睡眠型态紊乱的预防及对策

目的探讨控制和预防睡眠紊乱发生的方法.方法回顾分析我院76例肝移植术后患者睡眠型态紊乱的临床资料.结果对影响患者睡眠质量的5个因素进行针对性的护理,使76例肝移植术后患者获得良好的睡眠护理.结论提出了行之有效的措施,能够有效的预防和减少肝移植术后睡眠型态紊乱的发生.     

北京市大兴区2006—2010年手足口病分析及2011年发病趋势预测

目的了解北京市大兴区手足口病的发病规律,对2011年发病趋势做出预测,找出工作重点。方法利用SPSS及Excel软件,对经国家疾病监测信息报告管理系统报告的数据进行描述性统计。结果流动人口聚集程度越高,发病率越高（χ2=1740.82,P〈0.01）;外省户籍病例比例逐年增高,病例数涨幅高于该市病例;发病时间范围跨度增大,高峰提前,持续时间更长;EV71成为流行的病原。结论加强流动人口管理,开展健康教育与环境整治,持续监测病原,提高诊疗能力,是应对手足口病流行的重点工作。     

胰腺肿瘤有良性的吗

问：胰腺有没有良性肿瘤,都有哪些？ 答：胰腺的良性肿瘤有很多种,因为胰腺由外分泌腺和内分泌腺两部分组成,这两部分都可以生出相应的良性肿瘤。来自外分泌腺,较为常见的良性或低度恶性肿瘤包括胰腺囊腺瘤、胰腺囊腺癌、胰腺实性假乳头状瘤、胰腺导管内乳头状粘液性肿瘤;而来自内分泌腺,     

针灸治疗眼病临床应用规律分析

基于《中医针灸信息库》中的数据,采用文献计量分析方法,对1954至2016年间有关针灸治疗眼病的临床研究类论文进行文献计量分析与评价,以期客观地反映针灸治疗眼病的疾病谱和适宜病症。结果显示针灸治疗眼病的疾病谱共涉及13类疾病47个具体病症,总病例数为176 469,有效病例数为160 662,有效率为91.0%。针灸治疗眼病的适宜病症有近视、睑腺炎、结膜炎;常用适宜病症有斜视、干眼病、眼肌麻痹;次常用适宜病症有视神经萎缩、眼睑下垂、动眼神经麻痹、眼睑痉挛、弱视。针灸治疗眼病中最常用的体穴为攒竹、睛明、太阳,最常用的耳穴为眼、肝、肾。从配穴方法上来看,以局部用穴为主,同时以远端取穴辅助配合治疗。     

药用植物对干旱胁迫的响应及受控实验

作者从形态结构、生理反应、生化反应及分子机制等方面总结了近年来药用植物对干旱胁迫响应的研究成果,并结合药用植物自身的特点,初步探讨了药用植物干旱胁迫受控实验的关键环节,为揭示药用植物对干旱胁迫的响应提供理论依据。     

Influence of electroacupuncture on histomorphology of lacrimal glands and ocular surface in experimental dry eye syndrome

Objective

To observe the influence of electroacupuncture (EA) on histomorphologies of lacrimal glands, cornea and conjunctiva in experimental dry eye syndrome, and to explore the repair effects of EA on lacrimal glands and ocular surface damage.

Methods

Twenty-four healthy male New Zealand rabbits were randomly divided into a normal group, a model group, an EA group and a medication group, 6 rabbits in each group. Experimental dry eye syndrome models were prepared in rabbits by using 0.1% benzalkonium chloride for eye drops. Tear secretion volume, break-up time of tear film (BUT) and corneal fluorescein staining score were observed before and after the treatment. Periodic acid Schiff (PAS) staining method was used to observe the changes of conjunctival goblet cells in rabbits. After hematoxylin eosin (HE) staining, morphological changes of rabbit cornea, conjunctiva and lacrimal gland tissues were observed under light microscope.

Results

Compared with the normal group, tear secretion volume and BUT were significantly reduced (both P<0.01), while the corneal fluorescein staining score was significantly increased (P<0.01) in the model group. Compared with the model group, tear secretion volume and BUT were significantly increased, while the corneal fluorescein staining score was significantly decreased in the EA group and the medication group (all P<0.01). Compared with the normal group, the number of conjunctival goblet cells in the model group was significantly reduced; compared with the model group, the numbers of conjunctival goblet cells were all relatively higher in the EA group and the medication group. Pathological lesions of cornea, conjunctiva and lacrimal glands all showed improvement by HE staining in the EA group and the medication group after the intervention.

Conclusion

EA can improve tear secretion and tear film stability of rabbit dry eye syndrome, and repair the pathologic lesions of conjunctival goblet cells, corneal epithelia, cornea, conjunctiva and lacrimal glands.