A comparative study of some concurrency control algorithms for cluster-based communication networks

This paper presents a comparative study of some concurrency control algorithms for distributed databases of computer clusters which emphasize high availability and high performance requirements. For this purpose, we have analyzed some concurrency control algorithms which are used in commercial DBMSs, such as the pessimistic locking algorithm as it verifies transaction conflicts early in their execution phase, and the optimistic algorithm which investigates the presence of conflicts after the execution phase. A new algorithm is proposed and implemented by a simulation program. The three algorithms were tested using different configurations. Simulation results showed that the locking algorithm performed better than the optimistic method in presence of conflicts between transactions, while the optimistic algorithm provided better results in the absence of conflicts. Furthermore, in a distributed database with a certain probability of conflicts, the locking algorithm can be used to guarantee strong consistency and an acceptable level of performance. However, if this probability is negligible, the system performance can be improved by using the optimistic algorithm. The proposed algorithm offers improved performance in numerous cases. As a result, it can be used in a distributed database to guarantee a satisfactory level of performance in the presence of conflicts.     

Personality Organizations, Psychiatric Severity, and Self and Object Representations.

This study examined the hypothesis that psychotic, borderline, and neurotic personality organizations (POs) present a progressive differentiation between self and object representations and an increasing integration of their bad and good aspects. Fifty patients participated in the study. Measures included scales of self and object representations (S. J. Blatt, S. A. Bers, & C. E. Schaffer, 1993; S. J. Blatt, H. Wiseman, E. Prince-Gibson, & C. Gatt, 1991), as well as the Personality Organization Diagnostic Form (L. Diguer & L. Normandin, 1997) and estimations of psychiatric severity. Results showed that PO groups differed in terms of the integration of the object and its valence. It was also observed that although object and self representations were closely intertwined, the latter showed more discrimination between POs than the former. Psychiatric severity was shown to correlate more with object representations than self representations. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Computational modeling of flow over an ogee spillway

This paper presents an investigation into the hydraulics of regular ogee-profile spillways. The free-surfaces of the fluid for several flow heads as measured in the hydraulics laboratory are used as benchmarks. The finite element computational fluid dynamics software, ADINA, was used to predict the free surface over an ogee spillway and thus model the flow field. Since the actual flow is turbulent the k-ε flow model was used. For the cases considered in this paper, ADINA predicted reasonable free surface results that are consistent with general flow characteristics over spillways. The results are also in close agreement with measured free-surface profiles over the entire length of the spillway.     

Quantitative and reliable in vitro method combining scanning electron microscopy and image analysis for the screening of osteotropic modulators

The increased generation and up-regulated activity of bone resorbing cells (osteoclasts) play a part in the impairment of bone remodeling in many bone diseases. Numerous drugs (bisphosphonates, calcitonin, selective estrogen receptor modulators) have been proposed to inhibit this increased osteoclastic activity. In this report, we describe a pit resorption assay quantified by scanning electron microscopy coupled with image analysis. Total rabbit bone cells with large numbers of osteoclasts were cultured on dentin slices. The whole surface of the dentin slice was scanned and both the number of resorption pits and the total resorbed surface area were measured. Resorption pits appeared at 48 h and increased gradually up to 96 h. Despite the observation of a strong correlation between the total resorption area and the number of pits, we suggest that area measurement is the most relevant marker for osteoclastic activity. Osteotropic factors stimulating or inhibiting osteoclastic activity were used to test the variations in resorption activity as measured with our method. This reproducible and sensitive quantitative method is a valuable tool for screening for osteoclastic inhibitors and, more generally, for investigating bone modulators.     

Cryo-X-ray analysis-A novel tool to better understand the physicochemical reactions at the bioglass/biological fluid interface

The present study deals with the short-term physicochemical reactions at the interface between bioactive glass particles [55SiO(2)-20CaO-9P(2)O(5)-12Na(2)O-4MgO. mol%] and biological fluid (Dulbecco Modified Eagle's Medium (DMEM)). The physicochemical reactions within the interface are characterized by scanning transmission electron microscopy (TEM) (STEM) associated with Energy-dispersive X-ray spectroscopy (EDXS). Microanalysis of diffusible ions such as sodium, potassium, or oxygen requires a special care. In the present investigation the cryo-technique was adopted as a suitable tool for the specimen preparation and characterization. Cryosectioning is essential for preserving the native distribution of ions so that meaningful information about the local concentrations can be obtained by elemental microanalysis. The bioglass particles immersed in biological fluid for 24 h revealed five reaction stages: (i) dealkalization of the surface by cationic exchange (Na(+), Ca(2+) with H(+) or H(3)O(+)); (ii) loss of soluble silica in the form of Si(OH)(4) to the solution resulting from the breakdown of Si--O--Si bonds (iii); repolymerization of Si(OH)(4) leading to condensation of SiO(2)); (iv) migration of Ca(2+) and PO(4) (3-) to the surface through the SiO(2)-rich layer to form CaO-P(2)O(5) film; (v) crystallization of the amorphous CaO-P(2)O(5) by incorporating OH-- or CO(3) (2-) anions with the formation of three different surface layers on the bioactive glass periphery. The thickness of each layer is approximately 300 nm and from the inner part to the periphery they consist of Si--OH, which permits the diffusion of Ca(2+) and PO(4) (3-) ions and the formation of the middle Ca--P layer, and finally the outer layer composed of Na--O, which acts as an ion exchange layer between Na(+) ions and H(+) or H(3)O(+) from the solution.     

Academic trajectories of newcomer immigrant youth.

Immigration to the United States presents both challenges and opportunities that affect students' academic achievement. Using a 5-year longitudinal, mixed-methods approach, we identified varying academic trajectories of newcomer immigrant students from Central America, China, the Dominican Republic, Haiti, and Mexico. Latent class growth curve analysis revealed that although some newcomer students performed at high or improving levels over time, others showed diminishing performance. Multinomial logistic regressions identified significant group differences in academic trajectories, particularly between the high-achieving youth and the other groups. In keeping with ecological–developmental and stage–environment fit theories, School Characteristics (school segregation rate, school poverty rate, and student perceptions of school violence), Family Characteristics (maternal education, parental employment, and household structure), and Individual Characteristics (academic English proficiency, academic engagement, psychological symptoms, gender, and 2 age-related risk factors, number of school transitions and being overaged for grade placement) were associated with different trajectories of academic performance. A series of case studies triangulate many of the quantitative findings as well as illuminate patterns that were not detected in the quantitative data. Thus, the mixed-methods approach sheds light on the cumulative developmental challenges that immigrant students face as they adjust to their new educational settings. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Optimal adaptive server allocation in a network

This paper considers an adaptive version of the problem of Klimov. There are N nodes with a Bernoulli routing and exogenous Poisson arrival processes. The service times are independent and are identically distributed in each node, with an unknown distribution. There is a single server to be allocated in a nonpre-emptive way to the customers. The problem is to minimize the long term average waiting cost per unit of time, for given cost rates in the nodes.The result is that the certainty equivalence controller, that assigns the server optimally assuming that the sample means of the service times are the correct means, is optimal.The analysis is based on results about last exit times of random walks.     

Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation

CYP2J2 is the main epoxygenase in the heart that is responsible for oxidizing arachidonic acid to cis-epoxyeicosatrienoic acids (EETs). Once formed, EETs can then be hydrolyzed by soluble epoxide hydrolase (sEH, encoded by EPHX2) or re-esterified back to the membrane. EETs have several cardioprotective properties and higher levels are usually associated with better cardiac outcomes/prognosis. This study investigates how cardiovascular disease (CVD) can influence total EET levels by altering protein expression and activity of enzymes involved in their biosynthesis and degradation. Diseased ventricular cardiac tissues were collected from patients receiving Left Ventricular Assist Device (LVAD) or heart transplants and compared to ventricular tissue from controls free of CVD. EETs, and enzymes involved in EETs biosynthesis and degradation, were measured using mass spectrometric assays. Terfenadine hydroxylation was used to probe CYP2J2 activity. Significantly higher cis- and trans-EET levels were observed in control cardiac tissue (n = 17) relative to diseased tissue (n = 24). Control cardiac tissue had higher CYP2J2 protein levels, which resulted in higher rate of terfenadine hydroxylation, compared to diseased cardiac tissues. In addition, levels of both NADPH-Cytochrome P450 oxidoreductase (POR) and sEH proteins were significantly higher in control versus diseased cardiac tissue. Overall, alterations in protein and activity of enzymes involved in the biosynthesis and degradation of EETs provide a mechanistic understanding for decreased EET levels in diseased tissues.     

An Original and Efficient Antibiotic Adjuvant Strategy to Enhance the Activity of Macrolide Antibiotics against Gram-Negative Resistant Strains

Gram-negative bacteria were reported as a significant cause of infections in both community and nosocomial settings. Considered as one of the greatest threats to public health, the spread of bacteria drug resistance and the lack of effective alternative treatment options remains problematic. Herein, we report a promising strategy to combat Gram-negative resistant strains consisting of the combination of a macrolide antibiotic with a polyaminoisoprenyl adjuvant derivative leading to a significant decrease of antibiotic resistance.     

Real‐time hybrid control of electrohydraulic active suspension

Electrohydraulic actuators are an attractive choice for active suspension, because these systems provide a high power‐to‐weight ratio. However, their dynamics are highly nonlinear. In addition, the use of one simple controller for both position and force is complicated, because there is a compromise between them in the case of active suspension. Most existing controllers do not efficiently fulfill the requirements, because only one state variable is considered. In this paper, we address these problems by developing a new hybrid controller for both position and force and implementing it in a real‐time test bench. Our goal is to control the vertical position of the passenger seat while tracking the force transmitted to passengers and keeping it within tolerable and comfortable limits. Therefore, the proposed controller is a combination of two controllers. Its flexible structure redirects the control signal to control the proper controlled state variable. The real‐time results of the newly designed hybrid controller are compared with those obtained using a classical proportional integral derivative controller, because this is the most widely used controller in the industry. As expected, the proposed controller demonstrates better performance in real‐time operation. Copyright © 2017 John Wiley & Sons, Ltd.