Early-Life Development of the Bifidobacterial Community in the Infant Gut

The establishment of the gut microbiota poses implications for short and long-term health. Bifidobacterium is an important taxon in early life, being one of the most abundant genera in the infant intestinal microbiota and carrying out key functions for maintaining host-homeostasis. Recent metagenomic studies have shown that different factors, such as gestational age, delivery mode, or feeding habits, affect the gut microbiota establishment at high phylogenetic levels. However, their impact on the specific bifidobacterial populations is not yet well understood. Here we studied the impact of these factors on the different Bifidobacterium species and subspecies at both the quantitative and qualitative levels. Fecal samples were taken from 85 neonates at 2, 10, 30, 90 days of life, and the relative proportions of the different bifidobacterial populations were assessed by 16S rRNA–23S rRNA internal transcribed spacer (ITS) region sequencing. Absolute levels of the main species were determined by q-PCR. Our results showed that the bifidobacterial population establishment is affected by gestational age, delivery mode, and infant feeding, as it is evidenced by qualitative and quantitative changes. These data underline the need for understanding the impact of perinatal factors on the gut microbiota also at low taxonomic levels, especially in the case of relevant microbial populations such as Bifidobacterium. The data obtained provide indications for the selection of the species best suited for the development of bifidobacteria-based products for different groups of neonates and will help to develop rational strategies for favoring a healthy early microbiota development when this process is challenged.     

The Utility of Land-Surface Model Simulations to Provide Drought Information in a Water Management Context Using Global and Local Forcing Datasets

Drought diagnosis and forecasting are fundamental issues regarding hydrological management in Spain, where recurrent water scarcity periods are normal. Land-surface models (LSMs) could provide relevant information for water managers on how drought conditions evolve. Here, we explore the usefulness of LSMs driven by atmospheric analyses with different resolutions and accuracies in simulating drought and its propagation to precipitation, soil moisture and streamflow through the system. We perform simulations for the 1980-2014 period with SASER (5 km resolution) and LEAFHYDRO (2.5 km resolution), which are forced by the Spanish SAFRAN dataset (at 5km and 30km resolutions), and the global eartH2Observe datasets at 0.25 degrees (including the MSWEP precipitation dataset). We produce standardized indices for precipitation (SPI), soil moisture (SSMI) and streamflow (SSI). The results show that the model structure uncertainty remains an important issue in current generation large-scale hydrological simulations based on LSMs. This is true for both the SSMI and SSI. The differences between the simulated SSMI and SSI are large, and the propagation scales for drought regarding both soil moisture and streamflow are overly dependent on the model structure. Forcing datasets have an impact on the uncertainty of the results but, in general, this impact is not as large as the uncertainty due to model formulation. Concerning the global products, the precipitation product that includes satellite observations (MSWEP) represents a large improvement compared with the product that does not.

     

Designing biomass supply chains within planetary boundaries

The design of sustainable supply chains, which recently emerged as an active area of research in process systems engineering, is vital to ensure sustainable development. Despite past and ongoing efforts, the available methods often overlook impacts beyond climate change or incorporate them via standard life cycle assessment metrics that are hard to interpret from an absolute sustainability viewpoint. We here address the design of biomass supply chains considering critical ecological limits of the Earth—planetary boundaries—which should never be surpassed by anthropogenic activities. Our method relies on a mixed-integer linear program that incorporates a planetary boundaries-based damage model to quantify absolute sustainability precisely. We apply this approach to the sugarcane-to-ethanol industry in Argentina, identifying the optimal combination of technologies and network layout that minimize the impact on these ecological boundaries. Our framework can find applications in a wide range of supply chain problems related to chemicals and fuels production, energy systems, and agriculture planning.     

Mechanochemical tuning of molecular weight distribution of styrene homopolymers as postpolymerization modification in solvent-free solid-state

Mechanochemical degradation by planetary ball milling (PM) is used for postpolymerization modification of styrene homopolymers (PS). A complete factorial design was chosen to study the effect of radical scavengers, milling time, initial molecular weight, and revolution radius (R_p), on the shape of molecular weight distributions (MWDs) of PS. Size-exclusion chromatography analysis shows the feasibility of fine-tuning MWD of PS at up to 40% conversion. Distributions ranged from unimodal to bimodal in a PM with R_p = 150 mm at different stage of milling, whereas in a PM with R_p of 60.8 mm the adjustment of unimodal distributions is achieved. Initial polydispersity is more important to develop bimodal distributions when compared with initial molecular weight. Fourier transform infrared and X-ray electron spectrometry analysis show some suppression of PS degradation and complete oxidation inhibition of macromolecular radicals with the incorporation of radical scavengers, which we considered as additional aids when adjusting the MWDs.     

A Robust Controller for A 3‐DOF Flexible Robot with a Time Variant Payload

This article describes a new control scheme designed for a three degree of freedom (3‐DOF) flexible robot. The control scheme consists of two multi variable control loops. The inner loop is the motor's position control system, while the outer loop controls the robot tip's position, thus canceling vibrations which are originated by the structural flexibility of the manipulator during movement. As it will be shown, the outer control loop is robust to payload variations. The outer loop performance is based on a perfect cancelation of the inner loop dynamics. The effects of not achieving such perfect cancelation are also studied, and rules for designing a robust controller in this case are developed. Simulations assuming different payloads have been carried out with successful results for trajectory tracking. Trajectory tracking with a variable payload is also achieved.     

Long short-term cognitive networks

Neural Computing and Applications - In this paper, we present a recurrent neural system named long short-term cognitive networks (LSTCNs) as a generalization of the short-term cognitive network...     

Combining Support Vector Machines and simulated annealing for stereovision matching with fish eye lenses in forest environments

We present a novel strategy for computing disparity maps from omni-directional stereo images obtained with fish-eye lenses in forest environments. At a first segmentation stage, the method identifies textures of interest to be either matched or discarded. Two of them are identified by applying the powerful Support Vector Machines approach. At a second stage, a stereovision matching process is designed based on the application of four stereovision matching constraints: epipolarity, similarity, uniqueness and smoothness. The epipolarity guides the process. The similarity and uniqueness are mapped once again through the Support Vector Machines, but under a different way to the previous case; after this an initial disparity map is obtained. This map is later filtered by applying the Discrete Simulated Annealing framework where the smoothness constraint is conveniently mapped. The combination of the segmentation and stereovision matching approaches makes the main contribution. The method is compared against the usage of simple features and combined similarity matching strategies.     

A direct calculation of moments of the sample variance

A systematic method to deal with the interrelations of systems with multi-index quantities (random variables) is proposed. The method differs of the well-known Polykays. An application of the theoretical results here presented is the calculation of the moments of the sample variance for general populations in a direct way. The main advantage of the proposed methodology is that no conversion formulae and other complicated Polykays rules are needed. However, the proposed method is compatible with Polykays philosophy and conversion formulae and multiplication rules can be derived by using the theoretical results of this work. For practical purposes, two algorithms for the calculation of the moments of the sample variance are proposed.