Multi-objective Swarm Intelligence schedulers for online scientific Clouds

Cloud Computing is a promising paradigm for parallel computing. However, as Cloud-based services become more dynamic, resource provisioning in Clouds becomes more challenging. The paradigm, with its promise of virtually infinite resources, seems to suit well in solving resource greedy scientific computing problems. In a Cloud, an appropriate number of Virtual Machines (VM) is created and allocated in physical resources for executing jobs. This work focuses on the Infrastructure as a Service (IaaS) model where custom VMs are launched in appropriate hosts available in a Cloud to execute scientific experiments coming from multiple users. Finding optimal solutions to allocate VMs to physical resources is an NP-complete problem, and therefore many heuristics have been developed. In this work, we describe and evaluate two Cloud schedulers based on Swarm Intelligence (SI) techniques, particularly Ant Colony Optimization (ACO) and Particle Swarm Optimization (PSO). The main performance metrics to study are the number of serviced users by the Cloud and the total number of created VMs in online (non-batch) scheduling scenarios. We also perform a sensitivity analysis by varying the specific-parameter values of each algorithm to evaluate the impact on the performance of the two objective metrics. The intra-Cloud network traffic is also measured. Simulated experiments performed using CloudSim and job data from real scientific problems show that the use of SI-based techniques succeeds in balancing the studied metrics compared to Genetic Algorithms.     

Web-service based architecture to support SCM context-awareness and interoperability

Integration of Web-Services and “smart objects” in supply chain manufacturing systems (SCM) enables enterprise innovation and competitiveness in a globalized economy. The paper proposes a web-service based architecture for SCM that enables enterprises to develop context-awareness and to achieve interoperability at data, services, processes and business levels using event based web service notifications. The architecture is analyzed and implemented following the case study of an enterprise in the automotive industry.     

SaBRe: load-time selective binary rewriting

Binary rewriting consists in disassembling a program to modify its instructions. However, existing solutions suffer from shortcomings in terms of soundness and performance. We present SaBRe, a load-time system for selective binary rewriting. SaBRe rewrites specific constructs—particularly system calls and functions—when the program is loaded into memory, and intercepts them using plugins through a simple API. We also discuss the theoretical underpinnings of disassembling and rewriting. We developed two backends—for x86_64 and RISC-V—which were used to implement three plugins: a fast system call tracer, a multi-version executor, and a fault injector. Our evaluation shows that SaBRe imposes little overhead, typically below 3%.

     

Multimedia ontology population through semantic analysis and hierarchical deep features extraction techniques

Knowledge and Information Systems - The rapid increase of available data in different complex contexts needs automatic tasks to manage and process contents. Semantic Web technologies represent the...     

Atmospheric correction of optical imagery from MODIS and Reanalysis atmospheric products

In this paper we analyze the differences obtained in the atmospheric correction of optical imagery covering bands located in the Visible and Near Infra-Red (VNIR), Short-Wave Infra-Red (SWIR) and Themal-Infrared (TIR) spectral regions when atmospheric profiles extracted from different sources are used. In particular, three sensors were used, Compact High Resolution Imaging Spectrometer (CHRIS), Advanced Spaceborne Thermal Emission and Reflection radiometer (ASTER) and Landsat5 Thematic Mapper (TM), whereas four atmospheric profiles sources were considered: i) local soundings launched near the sensor overpass time, ii) Moderate Resolution Radiometer (MODIS) atmospheric profiles product (MOD07), iii) Atmospheric Correction Parameter Calculator (ACPC) generated by the National Center for Environmental Prediction (NCEP) and iv) Modified Atmospheric Profiles from Reanalysis Information (MAPRI), which includes data from NCEP and National Center of Atmospheric Research (NCAR) Reanalysis project but interpolated to 34 atmospheric levels and resampled to 0.5° × 0.5°. MODIS aerosol product (MOD04) was also used to extract Aerosol Optical Thickness (AOT) values at 550 nm. Analysis was performed for three test dates (12th July 2003, 18th July 2004 and 13th July 2005) over an agricultural area in Spain. Results showed that air temperature vertical profiles were similar for the four sources, whereas dew point temperature profiles showed significant differences at some particular levels. Atmospheric profiles were used as input to MODTRAN4 radiative transfer code in order to compute atmospheric parameters involved in atmospheric correction, with the aim of retrieving surface reflectances in the case of VNIR and SWIR regions, and Land Surface Temperature (LST) in the case of the TIR region. For the VNIR and SWIR region, significant differences depending on the atmospheric profile used were not found, particularly in the Visible region in which the AOT content is the main parameter involved in the atmospheric correction. In the case of TIR, differences depending on the atmospheric profile used were appreciable, since in this case the main parameter involved in the atmospheric correction is the water vapor content, which depends on the vertical profile. In terms of LST retrieval from ASTER data (2004 test case), all profiles provided satisfactory results compared to the ones obtained when using a local sounding, with errors of 0.3 K for ACPC and MAPRI cases and 0.7 K for MOD07. When retrieving LST from TM data (2005 test case), errors for MOD07 and MAPRI were 0.6 and 0.9 K respectively, whereas ACPC provided an error of 2 K. The results presented in this paper show that the different atmospheric profile sources are useful for accurate atmospheric correction when local soundings are not available. In particular, MOD07 product provides atmospheric information at the highest spatial resolution, 5 km, although its use is limited from 2000 to present, whereas MAPRI provides historical information from 1970 to present, but at lower spatial resolution.     

Shape and topology optimization for periodic problems

The present paper deals with the implementation of an optimization algorithm for periodic problems which alternates shape and topology optimization; the theoretical background about shape and topological derivatives was developed in Part I (Barbarosie and Toader, Struct Multidiscipl Optim, 2009). The proposed numerical code relies on a special implementation of the periodicity conditions based on differential geometry concepts: periodic functions are viewed as functions defined on a torus. Moreover the notion of periodicity is extended and cases where the periodicity cell is a general parallelogram are admissible. This approach can be adapted to other frameworks (e.g. Bloch waves or fluid dynamics). The numerical method was tested for the design of periodic microstructures. Several examples of optimal microstructures are given for bulk modulus maximization, maximization of rigidity for shear response, maximization of rigidity in a prescribed direction, minimization of the Poisson coefficient.     

Adjusting Some Properties of Poly(methacrylic acid) (Nano)Composite Hydrogels by Means of Silicon-Containing Inorganic Fillers

The present work aims to show how the main properties of poly(methacrylic acid) (PMAA) hydrogels can be engineered by means of several silicon-based fillers (Laponite XLS/XLG, montmorillonite (Mt), pyrogenic silica (PS)) employed at 10 wt% concentration based on MAA. Various techniques (FT-IR, XRD, TGA, SEM, TEM, DLS, rheological measurements, UV-VIS) were used to comparatively study the effect of these fillers, in correlation with their characteristics, upon the structure and swelling, viscoelastic, and water decontamination properties of (nano)composite hydrogels. The experiments demonstrated that the nanocomposite hydrogel morphology was dictated by the way the filler particles dispersed in water. The equilibrium swelling degree (SDe) depended on both the pH of the environment and the filler nature. At pH 1.2, a slight crosslinking effect of the fillers was evidenced, increasing in the order Mt < Laponite < PS. At pH > pKa_MAA (pH 5.4; 7.4; 9.5), the Laponite/Mt-containing hydrogels displayed a higher SDe as compared to the neat one, while at pH 7.4/9.5 the PS-filled hydrogels surprisingly displayed the highest SDe. Rheological measurements on as-prepared hydrogels showed that the filler addition improved the mechanical properties. After equilibrium swelling at pH 5.4, G’ and G” depended on the filler, the Laponite-reinforced hydrogels proving to be the strongest. The (nano)composite hydrogels synthesized displayed filler-dependent absorption properties of two cationic dyes used as model water pollutants, Laponite XLS-reinforced hydrogel demonstrating both the highest absorption rate and absorption capacity. Besides wastewater purification, the (nano)composite hydrogels described here may also find applications in the pharmaceutical field as devices for the controlled release of drugs.     

NH3-NO/NO2 SCR for diesel exhausts after treatment: mechanism and modelling of a catalytic converter

We review herein the key mechanistic and kinetic features of the reactions involved in the NH₃-NO/NO₂ SCR system investigated by dynamic reactive experiments over a V-based commercial powdered catalyst, eventually leading to the proposal of an original redox scheme which accounts for stoichiometry, selectivity and intrinsic kinetics of the global SCR process.     

Preliminary Evidence on the Diagnostic and Molecular Role of Circulating Soluble EGFR in Non-Small Cell Lung Cancer

Assessment of biological diagnostic factors providing clinically-relevant information to guide physician decision-making are still needed for diseases with poor outcomes, such as non-small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) is a promising molecule in the clinical management of NSCLC. While the EGFR transmembrane form has been extensively investigated in large clinical trials, the soluble, circulating EGFR isoform (sEGFR), which may have a potential clinical use, has rarely been considered. This study investigates the use of sEGFR as a potential diagnostic biomarker for NSCLC and also characterizes the biological function of sEGFR to clarify the molecular mechanisms involved in the course of action of this protein. Plasma sEGFR levels from a heterogeneous cohort of 37 non-advanced NSCLC patients and 54 healthy subjects were analyzed by using an enzyme-linked immunosorbent assay. The biological function of sEGFR was analyzed in vitro using NSCLC cell lines, investigating effects on cell proliferation and migration. We found that plasma sEGFR was significantly decreased in the NSCLC patient group as compared to the control group (median value: 48.6 vs. 55.6 ng/mL respectively; p = 0.0002). Moreover, we demonstrated that sEGFR inhibits growth and migration of NSCLC cells in vitro through molecular mechanisms that included perturbation of EGF/EGFR cell signaling and holoreceptor internalization. These data show that sEGFR is a potential circulating biomarker with a physiological protective role, providing a first approach to the functional role of the soluble isoform of EGFR. However, the impact of these data on daily clinical practice needs to be further investigated in larger prospective studies.     

Biosynthesis of the Myxobacterial Antibiotic Corallopyronin A

Corallopyronin A is a myxobacterial compound with potent antibacterial activity. Feeding experiments with labelled precursors resulted in the deduction of all biosynthetic building blocks for corallopyronin A and revealed an unusual feature of this metabolite: its biosynthesis from two chains, one solely PKS‐derived and the other NRPS/PKS‐derived. The starter molecule is believed to be carbonic acid or its monomethyl ester. The putative corallopyronin A biosynthetic gene cluster is a trans‐AT‐type mixed PKS/NRPS gene cluster, containing a β‐branching cassette. Striking features of this gene cluster are a NRPS‐like adenylation domain that is part of a PKS‐type module and is believed to be responsible for glycine incorporation, as well as split modules with individual domains occurring on different genes. It is suggested that CorB is a trans‐acting ketosynthase and it is proposed that it catalyses the Claisen condensation responsible for the interconnection of the two chains. Additionally, the stereochemistry of corallopyronin A was deduced by a combination of a modified Mosher's method and ozonolysis with subsequent chiral GC analyses.