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761.
An experimental program was carried out to clarify the structure-property relationships in fully-pearlitic steels of moderately
high strength levels, and to identify the critical microstructural features that control the deformation and fracture processes.
Specifically, the yield strength was shown to be controlled primarily by the interlamellar pearlite spacing, which itself
was a function of the isothermal transformation temperature and to a limited degree the prior-austenite grain size. Charpy
tests on standard and fatigue precracked samples revealed that variations in the impact energy and dynamic fracture toughness
were dependent primarily on the prior-austenite grain size, increasing with decreasing grain size, and to a lesser extent
with decreasing pearlite colony size. These trends were substantiated by a statistical analysis of the data, that identified
the relative contribution of each of the dependent variables on the value of the independent variable of interest. The results
were examined in terms of the deformation behavior being controlled by the interaction of slip dislocations with the ferrite-
cementite interface, and the fracture behavior being controlled by a structural subunit of constant ferrite orientation. Preliminary
data suggests that the size of such units are controlled by, but are not identical to, the prior-austenite grain size. Possible
origins of this fracture unit are considered. 相似文献
762.
763.
764.
Wassim M. Haddad Vijaya-Sekhar Chellaboina Dennis S. Bernstein 《Systems & Control Letters》1996,27(1)
In this paper we introduce new bounds for the real structured singular value. The approach is based on absolute stability criteria with plant-dependent multipliers that exclude the Nyquist plot from fixed plane curve shapes containing the critical point − + jO. Unlike half-plane and circle-based bounds the critical feature of the fixed curve bounds is their ability to differentiate between the real and imaginary components of the uncertainty. Since the plant-dependent multipliers have the same functional form at all frequencies, the resulting graphical interpretation of the absolute stability criteria are frequency independent in contrast to the frequency-dependent off-axis circles that arise in standard real-μ bounds. 相似文献
765.
AM Langevin DT Casto PJ Thomas SD Weitman C Kretschmar H Grier C Pratt R Dubowy M Bernstein S Blaney T Vietti 《Canadian Metallurgical Quarterly》1998,16(7):2494-2499
PURPOSE: A phase I trial of 9-aminocamptothecin (9-AC) was performed in children with solid tumors to establish the dose-limiting toxicity (DLT), maximum-tolerated dose (MTD), and the pharmacokinetic profile in children and to document any evidence of activity. PATIENTS AND METHODS: A 72-hour infusion of 9-AC dimethylacetamide formulation was administered every 21 days to 23 patients younger than 21 years of age with malignant tumors refractory to conventional therapy. Doses ranged from 36 to 62 microg/m2 per hour. Pharmacokinetics were to be performed in at least three patients per dose level. The first course was used to determine the DLT and MTD. RESULTS: Nineteen patients on four dose levels were assessable for toxicities. At 62 microg/m2 per hour, three patients experienced dose-limiting neutropenia and one patient experienced dose-limiting thrombocytopenia. Pharmacokinetics were performed on 15 patients (nine patients had complete sets of plasma sampling performed). The pharmacokinetics of both lactone and total 9-AC were highly variable. The percentage of 9-AC lactone at steady-state was 10.8% +/- 3.6%. Total 9-AC and its lactone form had a terminal half-life of 8.1 +/- 3.8 and 7.1 +/- 3.9 hours, respectively, and a volume of distribution at steady-state (Vdss) of 21.2 +/- 13.3 L/m2 and 135.3 +/- 52.5 L/m2, respectively. Hepatic metabolism and biliary transport had an important role in 9-AC disposition. CONCLUSION: The recommended phase II dose of 9-AC administered as a 72-hour infusion every 21 days to children with solid tumors is 52 microg/m2 per hour. Neutropenia and thrombocytopenia were dose limiting. 相似文献
766.
767.
An optical technique for measuring the thickness of silicon membranes and beams such as those used in micromechanical devices is presented. The measurement, based on reflectance spectrometry, is rapid and nondestructive. The reflectance-spectrometry technique can be used to measure silicon membrane thickness in the range from 0.1 to 5 μm 相似文献
768.
769.
D. A. Hardwick A. W. Thompson I. M. Bernstein 《Metallurgical and Materials Transactions A》1983,14(12):2517-2526
Two commercially-processed Al-6Zn-2Mg alloys, 7050 and a “low copper” 7050, were tested for susceptibility to embrittlement by precharged hydrogen and by simultaneous cathodic charging and straining (SET procedure). Specimens were heat treated to underaged, peak-strength aged, and overaged conditions. In 7050, the peak strength and overaged conditions were not embrittled by hydrogen, though underaged material showed marked embrittlement. All microstructures tested for the low-copper alloy were embrittled. The results agree with the microstructural rationale established through earlier work on 7075 and 2124 aluminum alloys, particularly with respect to the susceptibility of underaged material to hydrogen. As in earlier work, the extent of dislocation transport of hydrogen, and local hydrogen accumulation at grain boundaries, evidently controlled the extent and degree of brittle fracture. These three important alloys can now be ranked in the order 7050, 2124, 7075 of increasing relative susceptibility to theonset of stress corrosion cracking. 相似文献
770.
A novel micro-extrusion process (MEP) has been developed for micromachining applications. Extrusions on the micrometer scale were realized using the compressive stresses resulting from electromigration-induced mass transport in planarized conductors. Electromigration produced compressive stresses at the anodes of passivated metallic interconnects that exceeded the plastic deformation stress, and allowed extrusions to form through simple die patterns etched through the passivation at the anode ends of edge-displacement conductor segments 相似文献