600MW超临界直流锅炉汽温偏差的分析及改进

在对某600MW超临界四角切圆燃烧锅炉的汽温及烟温偏差进行研究的基础上,系统地分析了过热器出口汽温偏差及再热器出口烟温偏差形成的机理、影响因素和对策。认为炉膛出口气流的残余旋转是造成水平烟道区域烟温和气流速度偏差的根本原因。在采取有效措施后,过热器出口汽温偏差和再热器出口烟温偏差得以减弱。     

反应熔渗法制备纳米 MoSi2-SiC复合材料

运用Mo＋C坯体反应溶渗法，可以得到MoSi2-SiC复合材料，其基体相晶粒尺寸为150-600nm，反应生成的SiC相分布均匀，大小为30-160nm之间．该纳米MoSi2-SiC复合材料强度为214．8MPa，断裂韧性为4．1MPa·m^1／2，力学性能远高于单相材料．透射电镜研究表明，在复合材料中存在大量的层错和一些位错，也有孪晶存在．     

SiC/Fe界面固相反应模型

使用XRD、EPMA和SEM等研究了SiC/Fe界面固相反应产物的相组成、反应区的显微结构以及反应区中反应物原子的浓度分布。SiC/Fe界面固相反应形成Fe₃Si、Fe(Si)和石墨态C沉积物,Fe₃Si的形成为该反应提供了足够的热力学驱动力。1100°×3h热处理后,反应区由调整的C沉积物区/均匀的C沉积物区/无C沉积物区(从SiC侧至Fe侧)构成。建立SiC/Fe界面固相反应模型以解释SiC/Fe界面固相反应的微观机理。在SiC/Fe界面固相反应过程中,SiC分解是不连续的,从而在SiC界面前沿形成调整的C沉积物区独特结构。     

一种高可靠的多通道MAC协议

针对工业无线传感器网络的应用需求和射频环境特点,提出了一种高可靠的多通道MAC协议CHNP.协议中给出了一种基于协商模式通道切换机制的MAC架构,并基于该架构给出了一种通道切换模式选择算法和一种自适应传输机制.前者可以实现更高程度的并发传输,而后者可在动态变化的射频条件下自适应地选择高质量通道进行传输.仿真表明,与已有多通道协议相比,CHNP可大幅提高网络的吞吐量、分组到达率以及MAC层延迟性能,并具有更好的抗干扰能力.     

基于社交媒体大数据的交通感知分析系统

社交媒体数据中蕴含了丰富的交通状态信息,这些信息以人类语言为载体,包含了大量对交通状态的因果分析与多角度描述,可以为传统交通信息采集手段提供有力补充,近年来已成为交通状态感知的重要信息来源.本文以新浪微博为主要数据来源,分别利用支持向量机算法、条件随机场算法以及事件提取模型完成微博的分类、命名实体识别与交通事件提取,开发了基于社交媒体大数据的交通感知分析与可视化系统,可以为交通管理部门及时提供交通舆情及突发交通事件的态势、影响范围、起因等信息.在交通信息采集系统建设较为薄弱的地区,本文建立的系统可以为交通管理提供信息补充.     

Cryptanalysis and improvement of three-particle deterministic secure and high bit-rate direct quantum communication protocol

The three-particle deterministic secure and high bit-rate direct quantum communication protocol and its improved version are analyzed. It shows that an eavesdropper can steal the sender’s secret message by the intercept-resend attack and the entanglement attack. The original version is even fragile under denial-of-service attack. As a result, some suggestions to revise them are given.     

A potential antitumor drug (arginine deiminase) reengineered for efficient operation under physiological conditions

Arginine deiminase (ADI, EC 3.5.3.6) is a potential antitumor drug for the treatment of arginine‐auxotrophic tumors such as hepatocellular carcinomas (HCCs) and melanomas, and studies on human lymphatic leukemia cell lines have confirmed that ADI has antiangiogenic activity. Recent studies showed that a combination of taxane and ADI‐PEG20, which induces caspase‐independent apoptosis, is more effective than taxane monotherapy for prostate cancer. The main limitation of ADI from Pseudomonas plecoglossicida (PpADI) and of many other ADI enzymes lies in their pH‐dependent activity profile. PpADI has a pH optimum at 6.5 and a pH shift from 6.5 to 7.5 results in an ～80 % activity drop (the pH of human plasma is 7.35 to 7.45). In 2010, we reported a proof of concept for ADI engineering by directed evolution that resulted in variant M2 (K5T/D44E/H404R). M2 has a pH optimum of pH 7.0, a fourfold higher k_cat value than the wild‐type PpADI (pH 7.4, 0.5 M phosphate buffer), and an increased K_m value for substrate arginine. In our latest work, variants M5 (K5T/D38H/D44E/A128T/H404R) and M6 (K5T/D38H/D44E/A128T/E296K/H404R) were generated by directed evolution by employing PBS buffer (pH 7.4), which mimics physiological conditions. The S_0.5 value of parent M3 (K5T/D44E/A128T/H404R) decreased from 2.01 to 1.48 mM (M5) and 0.81 mM (M6). The S_0.5 value of M6 (0.81 mM ) is lower than that of wild‐type PpADI (1.30 mM ); the k_cat values improved from 0.18 s^?1 (wild‐type PpADI) to 17.56 s^?1 (M5, 97.6‐fold) and 11.64 s^?1 (M6, 64.7‐fold).     

Self-Thermophoretic Nanoparticles Enhance Intestinal Mucus Penetration and Reduce Pathogenic Bacteria Interception in Colorectal Cancer

Colorectal cancer (CRC) is the second most common cause of cancer incidence worldwide. Oral drug delivery systems (ODDS) have shown great promise for CRC therapy, but the delivery efficiency is still challenged by the dense intestinal mucus barrier and nonspecific interception of abnormally proliferated pathogenic bacteria. Herein, self-thermophoretic nanoparticles (CTPB) is presented to enhance intestinal mucus penetration and reduce pathogenic bacteria interception in CRC for efficient drug delivery. The nanoplatform introduces hollow mesoporous copper sulfide and is asymmetrically sprayed with titanium dioxide as the self-thermophoretic matrix. Based on the close relationship between pathogenic bacteria and CRC, the nanoplatform is camouflaged by the biomimetic membrane of Staphylococcus aureus to precisely anchor in the intestinal segment of CRC. After near-infrared laser irradiation, CTPB can effectively increase the intestinal mucus penetration efficiency by 2.7 folds, and decrease the pathogenic bacterial interception by 3.5 folds via the self-thermophoretic propulsion force. In orthotopic CRC-bearing mice, CTPB vastly improved the drug delivery efficiency to CRC after oral administration, thus showing a 99.4% antitumor rate after three weeks of treatment, which provides new insight into oral drug delivery for CRC therapy.     

High-dimensional deterministic multiparty quantum secret sharing without unitary operations

A deterministic multiparty quantum secret sharing scheme is put forward, in which Bell states in high-dimensional Hilbert space are used. Only by preforming High-dimensional Bell measurements, all agents can recover the secret according to the dealer??s announcement when collaborating with each other. It shows that unitary operation for encoding deterministic secret is unnecessary in quantum communication. The security of the transmission of the high-dimensional Bell states can be ensured by randomly using one of the two mutually unbiased bases for eavesdropping checking, and thus by which the proposed quantum secret sharing scheme is secure against usual attacks. In addition, the proposed scheme has three advantages: generality, high resource capacity and high security.     

块状均匀与非均匀材料中强超快脉冲的光谱分析

本文用变分法和快速傅里叶变换,分析了在块状均匀与非均匀材料中传输的强超快脉冲的光谱分布,修正了Manassah的错误结果。