High performance of boehmite/polyacrylonitrile composite nanofiber membrane for polymer lithium-ion battery

In this study, a novel boehmite/polyacrylonitrile (BM/PAN) composite nanofiber membrane was prepared using the electrospinning technique. The physical and electrochemical properties of different contents of BM/PAN composite nanofiber membranes were investigated as separators for lithium ion batteries (LIBs). Compared to the commercial polypropylene (PP) separator, the experimental results show that the BM/PAN composite nanofiber separator possesses a unique three-dimensional (3D) interconnected structure and exhibits higher porosity, greater electrolyte up-take, higher thermal stability and better electrochemical performance in a LiCoO₂/Li cell. Besides, batteries containing 30 wt% BM/PAN membranes display the highest ionic conductivity (2.85 mS cm⁻¹), widest electrochemical stability window (5.5 V vs. Li⁺/Li), leading to the highest initial discharge capacity (162 mA h g⁻¹) and the largest capacity retention ratio (90.7%) at 0.5C after 100 cycles. These findings reveal that the BM/PAN composite nanofiber membranes are promising candidates as commercial separators for high performance LIBs.

In this study, a novel boehmite/polyacrylonitrile (BM/PAN) composite nanofiber membrane was prepared using the electrospinning technique.     

基于时空分析的急诊护理人力资源管理

目的 探讨急诊患者的时空分布规律,优化急诊护理人力资源的管理。方法 回顾分析2017-2019年笔者所在医院急诊科就诊患者的资料,对患者每年不同月份、不同工作日、不同时间段及省内外就诊辐射特点进行时空分布的统计分析。结果 急诊患者就诊量呈逐年上升趋势,节假日的日均就诊量最高,就诊患者大部分集中在1-4月和9-12月,9∶00和20∶00是全天就诊的2个高峰时间点。空间上以笔者所在医院为中心就诊患者呈中心辐射状分布,人群主要为湖北省内患者为主,省内集中在武汉、黄冈、孝感等城市;省外以河南居首,其次为江西、湖南、浙江。结论 应根据患者的时空分布规律,科学合理地配置及利用护理人力资源,以保障患者安全和提高急救护理质量。     

Penile aseptic abscess in the cavernous body at the base of the penis:a case report

We report a case of aseptic abscess in the cavernous body at the base of the penis.In our clinical observation,the patient underwent puncture and drainage of the corpus cavernosum abscess,followed by surgical resection of the abscess wall,with the incisions closed layer by layer with primary suture.In addition,we paid attention to strengthening the postoperative management by using elastic bandages to wrap the penis intermittently to prevent edema;the incision would not be covered with dressings from the third day after the operation,so as to keep the incision site dry in an open way.During the period of indwelling of the catheter after the operation,we noticed the care of the external orifice of the urethra to reduce the occurrence of catheter-related infections.Finally,the patient was diagnosed with a penile aseptic abscess in the cavernous body at the base of the penis.The patient recovered well after surgery and was discharged 1 week later.At 1.5 years after the operation,the shape of the penis returned to normal,and the erectile function was normal.It was seen that good nursing concept is of great help for prognosis,which could avoid infection and edema,and is conducive to wound healing.     

Photoacoustic dual-scan mammoscope: results from 38 patients

We have developed a photoacoustics-based imaging system, the dual-scan mammoscope (DSM), that combines optical contrasts with acoustic detection, to obtain the angiographic features in human breast. In this study, we investigated whether the system can differentiate malignant tumor and healthy breast. We have imaged 38 patients with various tumor types and compared results of tumor-bearing breast with healthy breast for each patient. We also compared the photoacoustic and ultrasound imaging results with clinical US. Vascular features in and around the tumor mass were visualized. We found that tumor-bearing breast contained vessels of larger caliber and exhibited stronger variations in the background signals than those in the contralateral healthy breasts. Preliminary data on photoacoustic and ultrasound images also indicate that the technique has potential in differentiating different tumor types. Overall, our results indicate that combining photoacoustic and ultrasound images can improve breast cancer screening.     

Needle tract seeding of papillary thyroid carcinoma after fine-needle capillary biopsy: A case report

BACKGROUNDFine-needle biopsy is an accurate and cost-efficient tool for the assessment of thyroid nodules. It includes two primary methods: Fine-needle capillary biopsy (FNCB) and fine-needle aspiration biopsy. Needle tract seeding (NTS) is a rare complication of thyroid fine-needle biopsy mainly caused by fine-needle aspiration biopsy rather than FNCB. Here, we present an extremely rare case of a papillary thyroid carcinoma (PTC) patient with FNCB-derived NTS. CASE SUMMARYWe report a 32-year-old woman with PTC who showed subcutaneous NTS 1 year after FNCB and thyroidectomy. NTS was diagnosed based on clinical manifestations, biochemistry indices, and imaging (computed tomography and ultrasound). Pathological identification of PTC metastases consistent with the puncture path is the gold standard for diagnosis. Surgical resection was the main method used to treat the disease. After surgery, thyroid function tests and ultrasound scans were performed every 3-6 mo. To date, no evidence of tumor recurrence has been observed.CONCLUSIONFNCB is a safe procedure as NTS is rare, and can be easily removed surgically with no recurrence. Accordingly, NTS should not limit the usefulness of FNCB.     

侧卧位通气治疗新型冠状病毒肺炎重症患者的临床研究

目的探讨侧卧位通气对重症新型冠状病毒肺炎（COVID-19）患者的临床价值。 方法采用回顾性研究,收集2020年1月20日至3月7日在重庆三峡中心医院重症应急病区住院的41例COVID-19并中、重度急性呼吸窘迫综合征（ARDS）患者的临床资料。在经鼻高流量湿化氧疗（HFNC）或无创通气（NIV）的基础上,按是否进行侧卧位通气将患者分为侧卧位组（24例）和仰卧位组（17例）。统计2组患者的性别、年龄、急性生理与慢性健康状况（APACHEⅡ）评分和合并基础疾病情况,比较治疗前及治疗后第1、3、5天的心率（HR）、呼吸频率（RR）、氧合指数（PaO₂/FiO₂）、二氧化碳分压（PaCO₂）、平均动脉压（MAP）,以及轻症化率、HFNC或NPPV时间、气管插管发生率、住院时间、压疮发生情况等预后指标。 结果41例患者中,男性21例,女性20例;年龄43~79岁,平均（60.9±11.1）岁。2组患者年龄、性别、APACHEⅡ评分、合并基础疾病,以及治疗前RR、PaO₂/FiO₂、PaCO₂和MAP等比较,差异均无统计学意义（P均＞0.05）。2组患者治疗后HR、RR、MAP较治疗前下降,而PaCO₂、PaO₂/FiO₂上升,其中PaO₂/FiO₂在第5天较治疗前明显改善［侧卧位组：（166.4±45.4）mmHg vs（253.0±66.0）mmHg,仰卧位组：（183.8±54.4）mmHg vs（227.4±62.8）mmHg,P均＜0.05,1 mmHg=0.133 kPa］。2组间比较,侧卧位组在治疗后第1天RR较仰卧位组降低（P=0.006）;侧卧位组的中、重度ARDS患者PaO₂/FiO₂在治疗后第5天较仰卧位组改善,差异有统计学意义［（260.8±58.5）mmHg vs （221.6±64.9）mmHg,P=0.043］。2组HFNC或NIV时间和气管插管发生率比较,差异无统计学意义（P均＞0.05）,而侧卧位组总住院时间明显短于仰卧位组,差异有统计学意义［（15.5±7.2）d vs （21.5±9.8）d,P=0.028］,ICU住院时间也短于仰卧位组,差异有统计学意义［（10.3±6.3）d vs （16.9±11.0）d,P=0.021］,侧卧位组病死率低于仰卧位组,差异有统计学意义（8.3 % vs 23.5 %,P = 0.047）。 结论侧卧位通气能改善COVID-19并中、重度ARDS患者的氧合,缩短住院时间,降低病死率,提高疗效,促进患者康复。     

间充质干细胞在调节新型冠状病毒肺炎患者免疫功能中的应用

新型冠状病毒肺炎（COVID-19）是一种具有潜在致死性的传染性疾病,严重损害机体免疫系统,会导致免疫细胞过度激活,使炎性细胞因子大量释放,形成细胞因子风暴,从而加剧组织损伤和病情的发展。有效控制炎症因子风暴,已成为治疗COVID-19患者的关键点。间充质干细胞（MSCs）凭借其低免疫原性和对先天性和适应性免疫的调节能力,能够有效控制异常的免疫反应,抑制其对人体多器官造成的损伤。结合COVID-19患者免疫改变的特征和先前的研究,MSCs对COVID-19的治疗可能具有有良好的效果。本文通过分析COVID-19患者先天性和适应性免疫反应的改变,阐明MSCs对免疫的调节作用及机制,以期为COVID-19患者临床免疫治疗提供新的思路和理论基础。     

灼口综合征生物神经及社会心理性疾病模式的研究进展

灼口综合征(burning mouth syndrome,BMS)病因尚不明确,尚无有效的治疗方法,临床患者日渐增多。BMS是以舌部为主要发病部位,以烧灼样疼痛为典型表现的一组综合征。常不伴有明显的临床损害体征;无特征性的组织病理变化。由于持续的疼痛困扰以及不理想的用药效果,患者就医时往往有较高的期望值,就医后容易有较大的失望感,存在医患纠纷的隐患。作者对BMS的流行病学现状、临床表现、病因、分型、诊断标准及治疗等方面进行综述,以期对BMS的临床诊疗提供指导。     

The effects of cannabis use on oral health

Cannabis, also known as marijuana, is one of the most commonly used substances for medical and recreational purposes globally. With the trend of global legalization of medical use of cannabis and even the recreational use, the prevalence of recreational use of cannabis has increased markedly over the past few years. Correspondingly, the potential health concerns related to cannabis consumption have also increased. Therefore, it is necessary for oral healthcare providers to understand the effects of cannabis use on oral health. This review briefly summarizes the components of cannabis, biologic activities on tissues, and mechanisms of action in human cells and tissues. Oral tissue expression of cannabinoid receptors and the potential association of cannabis to oral diseases are also examined. The goals of this review are to (1) elaborate the basic biology and physiology of cannabis in human oral tissues, and (2) provide a better understanding the effects of its use and abuse on oral health. Due to insufficient information, more well‐designed studies should be conducted. It is urgent to include cannabis usage into dental patient health records.