动脉瘤性蛛网膜下腔出血后脑血管痉挛的低温治疗

脑血管痉挛(cerebral vasospasm,CVS)是导致动脉瘤性蛛网膜下腔出血(aneurysm subarachnoid hemorrhage,aSAH)患者死亡和残疾的主要原因之一.人们对SAH后CVS进行了广泛的研究,认为红细胞分解产物、血管内皮功能障碍以及分子机制在其发病起关键作用.目前对脑血管痉挛的治疗尚无确切治疗方法,近年来人们尝试应用低温治疗脑血管痉挛,现就SAH后CVS的病理生理机制和低温对于CVS的治疗进展作一综述.     

老年重症肌无力30例临床分析

重症肌无力是乙酰胆碱受体介导的神经肌肉接头处传递障碍的自身免疫性疾病，临床特征为部分或全身骨骼肌易于疲劳，常在活动后加重，休息后减轻具有晨轻暮晕等特点。近来一些研究认为，老年人群重症肌无力的发病率较预期要高，临床症状与年轻人也有着明显的不同。上述因素加上老年人常见的疾病谱，给老年人重症肌无力的诊断造成了很大的困难。而且随着社会年龄结构的改变，老龄化人口的比例不断增加，有必要对老年发病的重症肌无力予以重视。     

临时滤器预防肺栓塞162例的临床应用

下肢深静脉血栓(deep vein thrombosis,DVT)是引起肺动脉栓塞(pulmonary embolism,PE)的重要原因.我们对162例下肢急性或亚急性DVT患者治疗中采用临时滤器预防肺动脉栓塞,现报告如下.     

手术加中药治疗跟骨粉碎性骨折32例

跟骨骨折是常见的足部骨折，其中波及距下关节面的跟骨粉碎性骨折约占60％-70％，因而易引起多种并发症，治疗相当棘手。笔者自2000年1月～2007年5月采用手术加中药治疗跟骨粉碎性骨折32例34足，疗效较好，并与同期非手术治疗的26例28足进行对比观察，现报告如下。     

微创介入治疗儿童干骺端骨囊肿

目的 探讨微创治疗儿童干骺端骨囊肿的临床疗效。方法 2001年3月至2004年8月对11例儿童干骺端骨囊肿采用经血管栓塞联合经皮穿刺无水酒精灌洗或注射皮质类固醇固化治疗骨囊肿。结果 随访13个月～4年，平均20个月。11例病人病骨破坏全部终止，病症均缓解，影像检查8例病灶影像学全部修复，3例病灶大部分修复，均无骨囊肿复发，同时不影响骨骺的发育。结论 联合微创介入治疗干骺端骨囊肿是一种痛苦小、安全有效的治疗方法。     

直肠癌经腹切除未放置腹腔引流19例

我院2001年1月～2004年1月对19例直肠癌行经腹切除未放置腹腔引流，取得良好效果，现报告如下。     

Effects of penetrating cornea injury combined with seawater immersion on the levels of aqueous humor TNF-α in rabbits

Objective To observe effects of penetrating cornea injury combined with seawater immersion on the levels of aqueous humor TNF-α in rabbits. Methods 10 adult healthy grey rabbits were used for the experiment. The rabbit eye model of comea blast injury was developed by using a single firecracker. For each rabbit, the right eye was the experimental eye (seawater was injected into the anterior chamber through the cornea incision, simulating seawater immersion) and the left eye was the control (treated with 0.9% sodium chloride). Levels of aqueous humor TNF-α were detected by using double-antibody sandwich ELISA on the 1st, 2nd, yrd, 4th, 5th, and 7th days following seawater immersion or 0.9% sodium chloride injection. Results Following development of the model, levels of aqueous humor TNF-α in the experimental eye on the 1st, 2nd, 3rd days were 190.338, 156. 107,117.018 ng/L respectively, and significant differences could be seen when comparisous were made between the experimental and control eyes. The level of aqueous humor TNF-α on the 1st day was the highest and obviously reached the peak. Conclusions Level of aqueous humor TNF-α in the experimental eye with penetrating cornea injury combined with seawater immersion was significantly higher than that of the control eye, indicating that TNF-α was clearly involved in the pathological change and it played an important role in the process.