野生型P53基因导入对膀胱癌细胞生长抑制和H—ras基因表达调控

通过逆转录病毒载体的将外源野生型Ｐ５３基因导入膀胱癌细胞ＢＩＵ－８７和ＥＪ，使细胞在体外标准培养条件下生长速率降低，丧失裸鼠致瘤性。细胞周期分析显示Ｇ０＋Ｇ１细胞比率明显增高，已证明，ＢＩＵ－８７和ＥＪ细胞都有ｒａｓ基因突变和表达扩增。     

低钾与恶性心律失常——附2例报告

电解质素乱引起心律失常临床上常见,但引起恶性心律失常则少见。2例因低钾而引起恶性心律失常病例报告如下:1 临床资料 例1,女,67岁。因右上腹部阵发生性疼痛伴恶心呕吐二小时于1993年3月31日急诊入院。以在有慢性胆囊炎病史。在观察治     

中医中药治疗癌性疼痛的近况

癌性疼痛系指由于肿瘤压迫,侵犯有关组织神经所产生的疼痛,是恶性肿瘤的一个常见症状。特别是晚期恶性肿瘤,疼痛常成为患者较痛苦的主要见证。现代医学治疗癌     

用中医药理论指导中成药生产

<正> 中成药的最大特点,就是在中医药理论指导下研制、生产和运用的。在中成药生产过程中,始终都要遵循中医中药理论体系,唯有如此,才能生产出优质高效的中药制剂,推动中药制剂的继承、发扬和创新。本文拟从生产实际中论述中成药制备如何以中医药理论为指导。     

抗代谢药物防治白内障术后后囊混浊的研究进展

抗代谢药物防治白内障术后后囊混浊的研究进展涂良钰１李绍珍２白内障复明手术后的晶状体囊混浊可以导致后发障的发生。目前临床治疗仍以激光切开囊膜为主，手术为辅，常见的术后并发症向眼科学者提出了药物防治后囊混浊的课题。用抗代谢药物来抑制术后残留的晶状体上皮细...     

人胚胎和新生儿心室肌心钠素发生的电镜免疫细胞化学研究

用包埋后电镜免疫细胞化学方法，研究了不同胎龄胚胎及新生儿心室股纤维中心钠素的胚胎发生，对心肌纤维内心钠素颗粒进行了体视学分析及统计学处理。结果表明：随着胎龄增长，细胞内肌丝由稀疏逐渐增多然后形成肌原纤维，线粒体的数目也逐渐增多；心钠素颗粒于第５周开始出现，颗粒的数目随胎龄增加而逐渐减少。至妊娠７月时基本消失。     

内镜诊断胃息肉86例分析

随着内镜检查技术的进步,胃息肉的诊断率已明显提高.在内镜下所见的息肉与组织学检查相结合才有临床意义.现将我院经内镜诊断的胃息肉86例结合组织学检查结果进行分析.一、一般资料:1978年至1990年纤维内镜检查4652例次,诊断胃息肉者86例,占1.84%.其中男     

山羊急性心肌缺血时恶性心律不齐的发生和...

The coronary collateral circulation of goat is very spare, so myocardiac ischemia model of goat can simulate the patient previously with normal coronary circulation and suddenly developing complete occlusion of coronary arteries. In this study 80 Chengdu goats were used, and the branches of their left coronary artery were ligated. Ventricular tachycardia (VT) developed in 23 goats and ventricular fibrillation (VF) in 39 goats. VT and VF both occurred in the early phase of acute myocardial ischemia, and both had 6 min as the median time of onset. In 71 cases data on the weight of myocardiac ischemic area were collected, in which the weight percentage of ischemic area relating to the ventricles of 34 goats with VF was significantly higher than that of 37 goats without VF (35.4 +/- 2.4% vs 19.5 +/- 1.9%). After coronary ligation, 9 cases directly precipitated into VF which could not be defibrillated. In the remaining 62 cases, the weight percentage of ischemic area of 21 cases with VT was higher than that of 41 cases without VT (32.9 +/- 2.8% vs 20.9 +/- 2.1%). The relationships between the incidence of VT or VF and the weight percentage of ischemic area were fitted with logistic curve. The likelihood of occurrence of VT or VF is increased as the weight percentage of ischemia area goes up.