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101.
用环磷酰胺对荷瘤小鼠进行化疗同时配合扶正健脾汤进行治疗的疗效观察,证明扶正健脾汤具有减轻环磷酰胺的副作用,其表现为实验组小鼠的胸腺系数增大;脾内 IgG、IgM 阳性抗体形成细胞增多;肝内巨噬细胞的吞噬功能加强。提示扶正健脾汤具有拮抗环磷酰胺对骨髓、胸腺和脾脏的免疫抑制作用,为该方剂治疗肿瘤的临床应用提供实验依据。 相似文献
102.
目的:观察着色真菌蟾蜍分离株的致病性。方法:抽样取着色真菌蟾蜍分离株与标准人分离株对照,制成菌悬液,做小鼠腹腔接种,观察接种后小鼠的外观表现,做菌种逆培养和观察内脏病理变化。结果:蟾蜍分离株卡氏枝孢霉、疣状瓶霉、裴氏着色霉和甄氏外瓶霉与病人分离株一样,在接种28天后,均可从小鼠脏器逆培养出接种的菌种,并引起内脏病变,形成结核样肉芽肿,肉芽肿内均可查见棕黄色硬壳小体。而瓶霉和外瓶霉属菌种逆培养结果均阴性。结论:从野生蟾蜍分离出的卡氏枝孢霉、疣状瓶霉,裴氏着色霉和甄氏外瓶霉与病人分离株一样,对小鼠有致病性,故可能是人着色芽生菌病的致病菌。 相似文献
103.
本试验探讨了华南双季稻区利用亚种同杂种优势的特点和问题,结果表明:当前,两系亚种问杂种一代主要存在的问题是结实率低和谷草比低;籼粳交杂种易受环境条件的影响;每穗实粒数和单株有效穗数是决定单株产量的重要因子;每穗实粒数增加的关键在于结实率的提高,本文还就提高结实率和谷草比等问题提出了意见。 相似文献
104.
根据嗜肺军团菌基因组DNA的种特异性DNA片段序列,合成一对引物进行聚合酶链反应(PCR)。经琼脂糖凝胶电泳、EB染色结果表明,一条870bp的核苷酸区带为嗜肺军团菌1~14血清型菌株所共有。PCR检测水中军团菌,其敏感性为350cfu/ml,而用同位素标记探针、斑点杂交法检测,其敏感性为43cfu/ml。PCR检测人工感染嗜肺军团菌的豚鼠组织标本,阳性率为83.3%,而细菌分离培养的阳性率仅为26.6%。在现场调查中,用PCR法初步验证了一起由Lp10引起的军团菌病爆发。上述结果表明,PCR法能快速、敏感、特异性检测嗜肺军团菌感染。 相似文献
105.
106.
We present three unusual cases of molluscum contagiosum occurring in epidermal cysts. All of them are asymptomatic, elevated, oval nodules diagnosed clinically as epidermal inclusion cyst or prurigo nodularis. Histology showed true epidermal cysts containing molluscum bodies throughout the cyst wall and some type of laminated material within the cyst itself. The lesion, in all three cases developed in the pubic area of young adult men. 相似文献
107.
本文运用模糊数学原理,对东台市1993年7月份市面上的全脂乳粉抽查监测结果进行卫生质量综合评价,结果令人满意,从而为乳粉卫生质量评比建立了客观有效的评价模型。 相似文献
108.
Measurement of patient satisfaction is an essential part of health outcome assessment. The purpose of this study is (a) to compare the stability of an aggregate summary measure and two separate summary measures of patient satisfaction; and, (b) to examine causal effects between two separate summary measures at two points in time. Data were collected from 1,451 Medicare HMO beneficiaries. In conclusion, (a) separate summary measures are recommended for constructing the measure of patient satisfaction and (b) moderate causal relationships and cross-lagged effects between the patient satisfaction measures of qualify of care and access to care were found. 相似文献
109.
Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. 总被引:9,自引:0,他引:9
The mitogenic, chemotactic, and synthetic responses of rat periodontal ligament (PDL) fibroblastic cells to epidermal growth factor (EGF), transforming growth factor-beta (TGF-beta), recombinant human platelet-derived growth factor (rhPDGF)-AB, rhPDGF-BB, natural (n) PDGF-AB, and insulin-like growth factor-I (IGF-I) were examined in vitro using PDL cells obtained from the coagulum of healing tooth sockets. PDGFs and IGF-I have potent and comparable mitogenic effects on PDL fibroblastic cells. The maximum mitogenic effect of PDGFs was observed at the concentration of 10 ng/ml, whereas that of IGF-I was seen at concentrations higher than 100 ng/ml. In contrast, EGF induced moderate, and TGF-beta inhibitory mitogenic responses. The combination of rhPDGF-AB with either EGF or TGF-beta demonstrated comparable mitogenic potency, equivalent to the level of PDGF alone regardless of the mitogenic effect of other growth factors. The combination of rhPDGF-AB and IGF-I, however, showed a synergistic effect revealing the highest mitogenic effect among all individual growth factors as well as any combinations of the growth factors tested. Similarly, PDL fibroblastic cells demonstrated strong chemotactic responses to both IGF-I and PDGFs. The maximum effect was observed by IGF-I at concentrations higher than 10 ng/ml, followed by rhPDGF-BB at 0.1 ng/ml, rhPDGF-AB and nPDGF at concentrations ranging from 0.1 to 1 ng/ml. TGF-beta revealed no, and EGF slightly increased, chemotactic effects. IGF-I slightly enhanced the synthesis of total protein, whereas other factors had no significant effect. However, both rhPDGF-AB and TGF-beta stimulated collagen synthesis. On the other hand, IGF-I showed no effect on collagen synthesis, while EGF suppressed collagen synthesis. These findings suggest that rhPDGF-BB and IGF-I stimulate proliferation and chemotaxis of PDL fibroblastic cells. In addition, the combination of these growth factors further increases the mitogenic effect. rhPDGF-AB also stimulates collagen synthesis by PDL fibroblastic cells. Thus, rhPDGF-BB and IGF-I may have important roles in promotion of PDL healing, and consequently, may be useful for clinical application in periodontal regenerative procedures. 相似文献
110.
Arthroscopic all-inside repair techniques of lateral meniscus anterior horn tear: a technical note 总被引:1,自引:0,他引:1
Choon Key Lee Jeung Tak Suh Chong Il Yoo Hyung Lae Cho 《Knee surgery, sports traumatology, arthroscopy》2007,15(11):1335-1339
Although the conventional outside-in technique is especially useful for repairing tears in the anterior portion of the meniscus,
it has a disadvantage of making an additional 1–2 cm sized skin incision and tying knots subcutaneously over the capsule.
Therefore we devised two all-inside repair techniques of lateral meniscus anterior horn tear according to the site of meniscal
tear, meniscosynovial junction or red–red zone. Because these techniques are modified methods of the outside-in meniscal repair
using a spinal needle, they are as simple as conventional outside-in technique. In addition they have advantages of vertical
mattress suture, which is an important characteristic of the all-inside repair, and no additional incision. We recommend these
techniques as an alternative method for repairing an anterior horn tear of the lateral meniscus. 相似文献